Results 51 to 60 of about 953,209 (297)

CPX‐351 in High‐Risk Relapsed Pediatric Acute Leukemia: Real‐World Phase 1 Data Establishing the FDA‐Approved Dose

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Outcomes for pediatric relapsed/refractory (R/R) acute myeloid leukemia (AML) remain dismal. CPX‐351, a liposomal formulation of cytarabine and daunorubicin, may have less off‐target toxicities than traditional chemotherapies and has shown improved outcomes for adults with newly diagnosed therapy‐related AML.
Jonathan D. Bender   +17 more
wiley   +1 more source

Comparison of Myocardial Infarction Frequency in Normal and Late Period Populations After Carbon Monoxide Poisoning

open access: yesEurasian Journal of Emergency Medicine, 2023
Aim:Carbon monoxide (CO) poisoning is still an important factor in the rate of emergency visits. For this reason, we aimed to compare the incidence of myocardial infarction (MI) late after discharge of CO poisoning and its types as compared with the ...
Sedat Özbay
doaj   +1 more source

A conceptual model of mental illness stigma constructs [PDF]

open access: yes, 2015
poster abstractMental illness (MI) stigma negatively impacts a range of psychosocial and functional outcomes, and has yielded a significant volume of empirical literature.
Adams, Erin L., Salyers, Michelle P.
core  

Upacicalcet: A Novel Intravenous Calcimimetic Agent for Patients Undergoing Hemodialysis With Secondary Hyperparathyroidism

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa   +3 more
wiley   +1 more source

Incidence of different types of Myocardial Infarctions (MI) in diabetic and non-diabetic patients in cardiology unit of Lady Reading Hospital, Peshawar

open access: yesRehman Journal of Health Sciences, 2020
Introduction: In past few decades prevalence of diabetes in patients with myocardial infarction has been remarkably increased. Diabetes mellitus has been well defined as a cardiovascular determinant in emergent nations.
Sumbal Jamil, Mustajab Ghani
doaj   +1 more source

The neural correlates of speech motor sequence learning [PDF]

open access: yes, 2015
Speech is perhaps the most sophisticated example of a species-wide movement capability in the animal kingdom, requiring split-second sequencing of approximately 100 muscles in the respiratory, laryngeal, and oral movement systems. Despite the unique role
Beal, Deryk S.   +3 more
core   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Assessment of right atrial function in inferior wall AMI

open access: yesAsian Journal of Medical Sciences, 2022
Background: Approximately 30–50% of patients with inferior infarction have some involvement of the right ventricle. The right ventricular (RV) infarction almost invariably develops in association with a large infarction of the adjacent septum and ...
Abhijit Das   +2 more
doaj   +1 more source

Cerebral differences in explicit and implicit emotional processing - An fMRI study [PDF]

open access: yes, 2007
The processing of emotional facial expression is a major part of social communication and understanding. In addition to explicit processing, facial expressions are also processed rapidly and automatically in the absence of explicit awareness.
Brückmann, H.   +9 more
core   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

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