Results 31 to 40 of about 11,031 (188)

Architecture and development of olivocerebellar circuit topography

Frontiers in Neural Circuits, 2013
The cerebellum has a simple tri-laminar structure that is comprised of relatively few cell types. Yet, its internal micro-circuitry is anatomically, biochemically, and functionally complex.
Stacey L Reeber, Joshua J White, Nicholas A George-Jones, Roy V Sillitoe   +3 more
doaj   +1 more source

Modulation of Purkinje cell complex spike waveform by synchrony levels in the olivocerebellar system

Frontiers in Systems Neuroscience, 2014
Purkinje cells (PCs) generate complex spikes (CSs) when activated by the olivocerebellar system. Unlike most spikes, the CS waveform is highly variable, with the number, amplitude, and timing of the spikelets that comprise it varying with each ...
Eric J Lang, Tianyu eTang, Colleen Y Suh, Jianqiang eXiao, Yuriy eKotsurovskyy, Timothy A Blenkinsop, Sarah P Marshall, Izumi eSugihara   +7 more
doaj   +1 more source

Corollary discharge in precerebellar nuclei of sleeping infant rats

eLife, 2018
In week-old rats, somatosensory input arises predominantly from external stimuli or from sensory feedback (reafference) associated with myoclonic twitches during active sleep.
Didhiti Mukherjee, Greta Sokoloff, Mark S Blumberg   +2 more
doaj   +1 more source

Tropomyosin 1 Promotes Platelet Adhesion and Clot Contraction Separate from Its Roles in Developmental Hematopoiesis

Advanced Science, EarlyView.
ABSTRACT Genome‐wide association studies (GWAS) link the Tropomyosin 1 (Tpm1) locus to quantitative blood trait variation, but related mechanisms are unclear. Tpm1 encodes an actin‐binding protein that regulates actin filament diversity, cell adhesion, signaling, and actomyosin contractility.
Po‐Lun Kung, Victor Tsao, Alina D Peshkova, Oscar A. Marcos‐Contreras, Kim Ha, Brian M Dulmovits, Nkemdilim Okoli, Anvi Sinha, Gennadiy Fonar, Rong Qiu, Rolf D Bates, Janelle Yeboah, Carson Shalaby, Tyler Truex, Soomin Jeong, Edna C Hardeman, Peter W Gunning, Vladimir R Muzykantov, Jacob W Myerson, Christopher S Thom   +19 more
wiley   +1 more source

Cerebellar nuclei neurons show only small excitatory responses to optogenetic olivary stimulation in transgenic mice: in vivo and in vitro studies

Frontiers in Neural Circuits, 2016
To study the olivary input to the cerebellar nuclei (CN) we used optogenetic stimulation in transgenic mice expressing channelrhodopsin-2 (ChR2) in olivary neurons.
Huo eLu, Huo eLu, Bo eYang, Dieter eJaeger   +3 more
doaj   +1 more source

Labeling Quality or Quantity? The Differential Impact of Geographical Indications on Export Performance in Turkish Agri‐Food Products

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT This study investigates the impact of geographical indication (GI) certification on the export performance of Turkish agri‐food products by analyzing both trade volume and unit value dynamics. Drawing on monthly data from 2000 to 2024 across 22 GI‐certified products, the research employs product‐level regressions, fixed‐effects panel models ...
Ihlas Sovbetov, Muge Burcu Ozdemir
wiley   +1 more source

Oregano and thyme by-products of olive oil aromatization process with microwave assisted extraction as a rich source of bio-active constituents

Frontiers in Nutrition
IntroductionProcessing of Medicinal Aromatic Plants (MAPs) results in the production of a significant amount of by-products, which are not commercially exploitable.
Evanthia Dina, Antigoni Cheilari, Argyro Vontzalidou, Dimitra Karamani, Ioanna Diamanti, Panagiotis Bagatzounis, Ilias Giannenas, Katerina Grigoriadou, Nektarios Aligiannis   +8 more
doaj   +1 more source

The cerebellum: A neural system for the study of reinforcement learning

Frontiers in Behavioral Neuroscience, 2011
In its strictest application, the term reinforcement learning refers to a computational approach to learning in which an agent (often a machine) interacts with a mutable environment to maximize reward through trial and error.
Rodney A. Swain, Abigail L. Kerr, Richard F. Thompson   +2 more
doaj   +1 more source

Mechanisms Underlying Dopaminergic Regulation of Nicotine-Induced Kinetic Tremor

Frontiers in Pharmacology, 2022
Nicotine induces kinetic tremor, which resembles pharmacological features of essential tremors, via activating the inferior olive (IO) neurons. Since nicotine is known to enhance dopamine release by stimulating α4β2 and/or α6 nACh receptors, we examined ...
Masaki Kato, Naofumi Kunisawa, Saki Shimizu, Higor A. Iha, Yukihiro Ohno   +4 more
doaj   +1 more source

Improved Detection of Myositis‐Specific Autoantibodies Using Luciferase Immunoprecipitation Systems Assay: Comparison With Line Blot and Conventional Immunoprecipitation

Arthritis &Rheumatology, EarlyView.
Objective Myositis‐specific autoantibodies guide the diagnosis and classification of idiopathic inflammatory myopathies, but current immunoassays vary in accuracy, particularly for autoantibodies associated with interstitial lung disease. To compare the performance of the luciferase immunoprecipitation systems (LIPS) assay with line blot and ...
Peter D. Burbelo, Iago Pinal‐Fernandez, Maria Casal‐Dominguez, Xin Tian, Shijinqiu Gao, Neha Gupta, Eric W. Robbins, John A. Chiorini, Christopher A. Mecoli, Lisa Christopher‐Stine, Livia Casciola‐Rosen, Andrew L. Mammen, Sonye K. Danoff, Anthony F. Suffredini, Julio A. Huapaya   +14 more
wiley   +1 more source