Results 71 to 80 of about 1,191,697 (276)

Cerebellar hallmarks of conditioned preference for cocaine [PDF]

, 2014
Pavlovian conditioning tunes the motivational drive of drug-associated stimuli, fostering the probability of those environmental stimuli to promote and trigger drug seeking and taking.
Carbó Gas, María, Coria Ávila, Genaro A., De las Heras-Chanes, Joan, Gil-Miravet, Isis, Manzo, Jorge, MIQUEL, MARTA, Sanchis-Segura, Carla, Vázquez Sanromán, Dolores   +7 more
core   +2 more sources

The Generation of Phase Differences and Frequency Changes in a Network Model of Inferior Olive Subthreshold Oscillations

PLoS Comput. Biol., 2012
It is commonly accepted that the Inferior Olive (IO) provides a timing signal to the cerebellum. Stable subthreshold oscillations in the IO can facilitate accurate timing by phase-locking spikes to the peaks of the oscillation. Several theoretical models
B. Torben-Nielsen, Idan Segev, Y. Yarom
semanticscholar   +1 more source

Left ventricular function improvement during angiotensin receptor–neprilysin inhibitor treatment in a cohort of HFrEF/HFmrEF patients

ESC Heart Failure, Volume 12, Issue 2, Page 1151-1165, April 2025.
Prediction of LVEF improvement in patients with HFrEF and HFmrEF following treatment with Sacubitril/Valsartan. Workflow of this study investigating the functional capacity improvement in response to Sacubitrail/Valsartsan in a real‐world scenario of heart failure treatment.
Florian Appenzeller, Tobias Harm, Manuel Sigle, Parwez Aidery, Klaus‐Peter Kreisselmeier, Livia Baas, Andreas Goldschmied, Meinrad Paul Gawaz, Karin Anne Lydia Müller   +8 more
wiley   +1 more source

A Comprehensive Review of Biotechnological Innovations in Valorization of Food Waste: Enhancing Nutritional, Techno‐Functional Properties, and Process Optimization for Sustainable Product Development

Food Frontiers, EarlyView.
This review highlights recent biotechnological innovations in the valorization of food waste through enzyme‐assisted processing and microbial fermentation to enhance nutritional, techno‐functional, and shelf‐stable properties for developing sustainable, plant‐based functional foods and nutraceuticals.
Md. Sakhawot Hossain, Md Abdul Wazed, Mst. Sultana Akhter Preya, Zakia Sultana, Md. Mostafa Kamal, Tanvir Ahmad, Islam Md Shimul   +6 more
wiley   +1 more source

Sensory prediction or motor control? Application of Marr-Albus type models of cerebellar function to classical conditioning

Frontiers in Computational Neuroscience, 2010
Marr-Albus adaptive filter models of the cerebellum have been applied successfully to a range of sensory and motor control problems. Here we analyze their properties when applied to classical conditioning of the nictitating membrane response in rabbits ...
Nathan F Lepora, John ePorrill, Chris eYeo, Paul eDean   +3 more
doaj   +1 more source

Harmaline attenuates voltage--sensitive Ca(2+) currents in neurons of the inferior olive.

Journal of Pharmacy & Pharmaceutical Sciences, 2012
PURPOSE Harmaline is one member of a class of tremorgenic harmala alkaloids that have been implicated in neuroprotective effects and neurodegenerative disorders.
Xiping Zhan, W. Graf
semanticscholar   +1 more source

Specificity of Inferior Olive Response to Stimulus Timing

Journal of Neurophysiology, 2008
The inferior olive is the sole source of the climbing fiber system, one of the two major afferent systems of the cerebellum; however, its exact role remains unknown. A longstanding hypothesis is that the inferior olive with its unique intrinsic rhythmic firing properties mediates motor timing.
T, Liu, D, Xu, J, Ashe, K, Bushara
openaire   +3 more sources

Electrophysiological Properties of Inferior Olive Neurons: A Compartmental Model [PDF]

Journal of Neurophysiology, 1999
As a step in exploring the functions of the inferior olive, we constructed a biophysical model of the olivary neurons to examine their unique electrophysiological properties. The model consists of two compartments to represent the known distribution of ionic currents across the cell membrane, as well as the dendritic location of the gap junctions and ...
N, Schweighofer, K, Doya, M, Kawato
openaire   +2 more sources

Efficient Numerical Framework for Geothermal Energy Production Optimization in Fracture‐Controlled Reservoirs

International Journal for Numerical Methods in Fluids, EarlyView.
We introduce an efficient open‐source numerical framework for the automated search for the placements of injection and production wells in hot fracture‐controlled reservoirs that sustainably optimize geothermal energy production. We model the reservoirs as discrete fracture networks in 3D. The fluid flow and heat transport in the reservoirs are modeled
Ondřej Pártl, Ernesto Meneses Rioseco
wiley   +1 more source

A cerebellar neuroprosthetic system: computational architecture and in vivo experiments

Frontiers in Bioengineering and Biotechnology, 2014
Emulating the input-output functions performed by a brain structure opens the possibility for developing neuro-prosthetic systems that replace damaged neuronal circuits.
Ivan eHerreros Alonso, Andrea eGiovannucci, Andrea eGiovannucci, Aryeh H Taub, Roni eHogri, Ari eMagal, Simeon A Bamford, Robert ePrueckl, Paul F.M.J. Verschure, Paul F.M.J. Verschure   +9 more
doaj   +1 more source