Results 81 to 90 of about 53,082 (276)

Design of Experiments (DoE)‐Optimized Polymeric Oxytocin Nanoparticles for Enhanced Nose‐to‐Brain Delivery

open access: yesSmall, EarlyView.
Intranasal (IN) delivery of PEGylated PLGA nanoparticles (NPs) loaded with oxytocin (OT) (OT‐NP‐PEG) is investigated as a strategy to enhance OT transport to the brain for treating autism and other neuropsychiatric disorders. The optimized NP formulation demonstrates appropriate physicochemical characteristics, improved stability, and enhanced mucosal ...
Naveed Ahmad   +11 more
wiley   +1 more source

Aspiration Thrombectomy in a Patient with Suprarenal Inferior Vena Cava Thrombosis

open access: yesCase Reports in Cardiology, 2015
DVT has rarely been observed in the inferior vena cava (IVC). Pulmonary embolism (PE), which can be life-threatening, often occurred in patients with IVC thrombosis.
Hideyuki Kishima   +7 more
doaj   +1 more source

Surgical removal of an inferior vena cava filter with duodenal penetration.

open access: yesInteractive Cardiovascular and Thoracic Surgery, 2018
Complications due to long-term implantation of inferior vena cava (IVC) filters have increased. Among these, IVC wall penetration by struts can lead to penetration of adjacent structures, which can be fatal to the patient.
Jong Seok Lee   +3 more
semanticscholar   +1 more source

Deep learning‐enhanced 3D imaging unveils semaglutide impact on cardiac fibrosis

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Myocardial fibrosis (MF), a hallmark of structural cardiac remodelling, drives disease progression across most forms of heart failure and plays a central role in heart failure with preserved ejection fraction (HFpEF). Despite its clinical relevance, effective treatments remain scarce.
Sheyla Barrado‐Ballestero   +11 more
wiley   +1 more source

Mitochondrial Ca2+ overload is a pivotal risk factor for lethal ventricular arrhythmias due to the oxidation of mitochondrial respirasome and energetic failure

open access: yesBritish Journal of Pharmacology, EarlyView.
The data that support the findings of this study are available from the corresponding author upon reasonable request. Some data may not be made available because of privacy or ethical restrictions. Background and Purpose Ventricular arrhythmias are a leading cause of death among patients with cardiovascular diseases and are associated with elevated ...
Felipe de Jesús Salazar‐Ramírez   +13 more
wiley   +1 more source

Tine after tine: a varied approach to the removal of a long-standing IVC filter

open access: yesRadiology Case Reports, 2017
Inferior vena cava filters are important tools used to help prevent life-threatening pulmonary embolisms in hospitalized patients with contraindications to pharmacological prophylactic anticoagulation.
Andrew Delozier   +2 more
doaj   +1 more source

Pharmacological inhibition of hydroxysteroid 11‐beta dehydrogenase type 1 (11‐βHSD1) after myocardial infarction preserves cardiac function in a translational mini‐pig model

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Plasma glucocorticoids increase acutely after MI, thereafter tissue levels are amplified selectively within cells expressing 11‐ßhydroxysteroid dehydrogenase type 1 (11‐ßHSD1) that regenerates active glucocorticoids from circulating metabolites.
Sara Al Disi   +19 more
wiley   +1 more source

Hemopericardium and Cardiac Tamponade Secondary to Migrated Inferior Vena Cava Filter

open access: yesCase Reports in Cardiology, 2018
A 73-year-old female presented with cardiogenic shock secondary to hemopericardium and cardiac tamponade. Imaging revealed two fractured legs of an inferior vena cava filter, with one leg within the anterior myocardium of the right ventricle and another ...
Jeet J. Mehta   +4 more
doaj   +1 more source

Transcriptomic Remodeling of Pulmonary Vein Sleeves Suggests a Role in Atrial Arrhythmogenesis in Thoroughbred Horses

open access: yesAnnals of the New York Academy of Sciences, EarlyView.
Myocardial sleeves of the pulmonary veins in racehorses with paroxysmal atrial fibrillation exhibit upregulated pathways associated with tissue structure remodeling. Pathways related to the extracellular matrix and cellular components differ significantly from those in healthy horses.
Magdalena Arevalo‐Turrubiarte   +8 more
wiley   +1 more source

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