Results 121 to 130 of about 186,449 (308)

Multi‐scale Engineered Vasculature and Hierarchical Porosity via Volumetric Bioprinting‐Guided Photopolymerization‐Induced Phase Separation

open access: yesAdvanced Materials, EarlyView.
Vascularization in bioprinted hydrogels is limited by nanoscale porosity in hydrogel bionks. Volumetric bioprinting of gelatin–norbornene phase‐separating hydrogels permits to create centimeter‐scale constructs featuring interconnected multi‐scale porosity. Light dose gradients result in spatially controlled pore dimensions. Capillary‐scale vessels are
Oksana Y. Dudaryeva   +8 more
wiley   +1 more source

Ovarian reserve and stimulation response before chemotherapy treatment in breast cancer patients undergoing fertility preservation: a historical cohort study

open access: yesJournal of Ovarian Research
Background Fertility preservation is an important aspect of care for breast cancer patients. This study was designed to compare the ovarian function including ovarian reserve and ovarian stimulation response in breast cancer patients undergoing ...
Nadia Jahangiri   +6 more
doaj   +1 more source

Implantable Microarray Patch: Engineering at the Nano and Macro Scale for Sustained Therapeutic Release via Synthetic Biodegradable Polymers

open access: yesAdvanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
This review focuses on the application of synthetic biodegradable microarray patches (MAPs) in sustained drug delivery. Compared to conventional MAPs which release drugs into the skin in an immediate manner, these implantable MAPs release drugs into skin microcirculation gradually as the biodegradable polymers degrade, thus offering sustained release ...
Li Zhao   +6 more
wiley   +1 more source

ICSI Outcome in Infertile Couples with Different Causes of Infertility: A Cross-Sectional Study [PDF]

open access: yesInternational Journal of Fertility and Sterility, 2013
Background: Different success rate of Intracytoplasmic Sperm injection (ICSI) has been observed in various causes of infertility. In this study, we evaluated the relation between ICSI outcome and different causes of infertility.
Mahnaz Ashrafi   +4 more
doaj  

Excessive DNA Double‐Strand Breaks–Associated 3D Genome Reorganization Contributes to Neural Tube Defects with Folate Deficiency

open access: yesAdvanced Science, EarlyView.
Neural tube defects (NTDs) are among the most common congenital malformations. However, the underlying etiology and mechanism remain elusive. Here, the role of DNA double‐strand breaks (DSBs) in 3D genome organization within the NTDs with folate deficiency is reported.
Ting Zhang   +12 more
wiley   +1 more source

Female infertility

open access: yes, 2014
Segundo dados da Organização Mundial da Saúde, estima-se que entre 60 e 80 milhões de pessoas em todo o mundo enfrentem dificuldades para levar a cabo seu projeto de paternidade e maternidade em algum momento da vida. Desejar ter filhos mas se deparar com a impossibilidade desse processo produz uma ampla gama de sentimentos, tais como medo, ansiedade ...
Demarque , Renata   +8 more
openaire   +1 more source

Integrin α8‐Mediated Pericyte Morphogenesis Controls Blood‐Brain Barrier Integrity

open access: yesAdvanced Science, EarlyView.
This study highlights that ITGA8 impacts pericyte morphology and function, both crucial for BBB integrity, via RhoA/ROCK signaling, thus influencing TGF‐β1 activation through cytoskeletal tension and ECM interactions. Notably, in post‐ischemic recovery models, ITGA8 deficiency exacerbates vascular dysfunction by impairing pericyte‐mediated BBB ...
Chang‐Xiong Gong   +16 more
wiley   +1 more source

The role of conception type in the definition of primary and secondary infertility

open access: yesInternational Journal of Reproductive BioMedicine, 2018
Uniform and definitive terminology in reproductive medicine is important for appropriate timing in starting an infertility workup to avoid over- and under-treatment, their related financial burden and psychological pressures (1, 2) and comparison of ...
Firouzeh Ghaffari, Arezoo Arabipoo
doaj  

Pre‐Administration of Akkermansia Muciniphila Prevents the Development of Severe Acute Graft‐Versus‐Host Disease in Systemic Organs

open access: yesAdvanced Science, EarlyView.
Akkermansia muciniphila, a next‐generation probiotic, alleviates acute graft‐versus‐host disease (aGvHD) following allogeneic hematopoietic stem cell transplantation (HSCT) by providing protective effects across multiple organs. Pre‐colonization with A.
Jeong‐Eun Han   +9 more
wiley   +1 more source

Minimally Invasive Chemical Biopsy Needle with Self‐Wettable Extraction Phase For In Vivo Tissue Sampling During Medical Procedures

open access: yesAdvanced Science, EarlyView.
A new tissue sampling device using an acupuncture needle with bio‐compatible extraction sorbents in the recessed section is developed. The coating material using self‐wettable particles doesn't require solvent activation after sterilization. This device is applied for the anti‐cancer drug concentration monitoring during the in vivo lung perfusion ...
Runshan Will Jiang   +9 more
wiley   +1 more source

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