Results 61 to 70 of about 97,210 (219)

Mesenchymal Stem Cell‐Derived Apoptotic Micro‐Vesicles Repaired Sciatic Nerve Defect by Regulating Early Inflammatory Microenvironment and Promoting Angiogenesis

Advanced Healthcare Materials, EarlyView.
HUCMSC‐Apo‐mvs enhance peripheral nerve repair by modulating the inflammatory microenvironment (IME), primarily through coordinated actions on three functional cells. They recruit macrophages and promote their polarization from pro‐inflammatory M1 to anti‐inflammatory M2 phenotypes, increasing secretion of IL‐10 and VEGF.
Haolin Liu, Yiben Ouyang, Bo Wang, Xiaochun Zhang, Yanjun Guan, Ruichao He, Yuhui Cui, Junli Wang, Qianru Yao, Yixiao Tan, Xiwei Peng, Xing Xiong, Sice Wang, Dongdong Li, Haofeng Cheng, Tianqi Su, Xiaoyang Fu, Jinjuan Zhao, Mingqian Yu, Yi Wang, Jiang Peng, Yu Wang   +21 more
wiley   +1 more source

Recurrent Implantation Failure from an Immunological Point of View [PDF]

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd
Introduction: Repeated implantation failure (RIF) is one of the main challenges in modern infertility treatments. Although assisted reproductive technology (ART) has undergone a lot of progression over the last recent years, some women still experience ...
Soolmaz Habibi, Fariba Ramezanali, Parisa Mostafaei, Elham Amirchaghmaghi   +3 more
doaj  

Microneedle Technology in Psoriasis Management: Mechanistic Insights, Technological Innovation, Clinical Progress, and Challenges

Advanced Healthcare Materials, EarlyView.
This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad, Yasmine Ruel, Roxane Pouliot, Davide Brambilla   +3 more
wiley   +1 more source

An Approach to Improve Endometrial Receptivity: Is It Beneficial to Flush The Uterine Cavity with Follicular Fluid and Granulosa Cells? A Phase III Randomised Clinical Trial [PDF]

International Journal of Fertility and Sterility
Background: The follicular fluid (FF) of mature oocytes contains a high concentration of growth factors and cytokinesthat have the potential to influence implantation in either a paracrine or autocrine manner.
Elham Hosseini, Samaneh Aghajanpour, Zahra Chekini, Nadia Zameni, Zahra Zolfaghary, Reza Aflatoonian, Maryam Hafezi   +6 more
doaj   +1 more source

Human closed and open apex premolar teeth express different toll‐like receptor

Molecular Genetics & Genomic Medicine, 2020
Background The innate immune activation which promotes inflammation responses in the dental pulp tissue leads to the progression of dentin caries.
Reza Jafari, Razieh Karamzadeh, Faezeh Pesaran Hajabbas, Fereshteh Sayyadizadeh, Zahra Chekini, Samaneh Aghajanpour, Leila Shakeri, Kiumars Nazarimoghaddam, Reza Aflatoonian   +8 more
doaj   +1 more source

A Synovium‐on‐Chip Platform to Study Multicellular Interactions in Arthritis

Advanced Healthcare Materials, EarlyView.
The Synovium‐on‐Chip comprises a thin microporous PDMS membrane to support co‐culture of fibroblast‐like synoviocytes (FLS), THP‐1‐derived macrophages, and endothelial cells, enabling real‐time analysis of synovial‐vascular interactions. FLS migration through the pores drives endothelial remodeling, while TNF‐α stimulation induces robust inflammatory ...
Laurens R. Spoelstra, Fleur R. Semmekrot, Nuno Araújo‐Gomes, Daniël Wijnperle, Monique M. A. Helsen, Martijn H.J. Van Den Bosch, Loes. I. Segerink, Séverine Le Gac, Marcel Karperien   +8 more
wiley   +1 more source

Start, Stop, Rewind, Repeat—Cyclic Exposure of Adipose Stromal Cells‐derived Cartilage Organoids to Chondrogenic and Proliferative Cues to Achieve Scaled‐up and Customizable Bone Formation by Endochondral Ossification

Advanced Healthcare Materials, EarlyView.
This study exploits the plasticity of ASCs‐derived cartilage organoids which generate a perichondrial layer of MSCs when exposed to cyclic chondrogenic/proliferative cues. Using these organoids as building blocks, we develop (i) Phalange Shaped Tissue Engineered Cartilage (Pa‐TECs), recapitulating endochondral ossification suitable for the treatment of
Pablo Pfister, Emilien Lhospice, Andrés García‐García, Robert Paillaud, Sebastian Jung, Romain Schaller, Elisabeth A. Kappos, Claude Jaquiéry, Tarek Ismail, Dirk J. Schaefer, Michael de Wild, Ivan Martin, Alexandre Kaempfen, Arnaud Scherberich, Adrien Moya   +14 more
wiley   +1 more source

The Translation and Cross-Cultural Adaptation of The Persian Version of The WERF EPHect Endometriosis Patient Questionnaire: A Cross-Sectional Study [PDF]

International Journal of Fertility and Sterility
Background: The World Endometriosis Research Foundation (WERF) Endometriosis Phenome and BiobankingHarmonisation Project (EPHect) aims to facilitate international research on endometriosis by developinga standardized questionnaire.
Arezoo Arabipoor, Kiandokht Kiani, Abbas Ebadi, Ashraf Moini, Zahra Zolfaghari, Mohadeseh Goudarzi   +5 more
doaj   +1 more source

Medical Fabrics with Non‐Antibiotic, Supramolecular Antimicrobial Coatings: A Preventive Approach to Combat Biofilm Formation and Bacterial Dissemination

Advanced Healthcare Materials, EarlyView.
The study presents an antibiotic‐free strategy using medical fabrics coated with supramolecular assemblies of polyarginine and hyaluronic acid. These coatings showed strong antimicrobial and anti‐biofilm activity in vitro and in vivo, achieving major bacterial load reductions, including against MRSA.
Adjara Diarrassouba, Abdessalem Rekiki, Cécile Loubière, Sabine Kuchler‐Bopp, Lauriane Petit, Cynthia Calligaro, Derry Mercer, Aurore Gaudin, Naomi Canourgues, Emilie Adicéam, Benoit Beitz, Jeremy Welsch, Annabelle Vigué, Markus j. Kettel, Michael Karl, Chloé Guilbaud‐Chéreau, Philippe Lavalle, Nihal Engin Vrana, Skander Hathroubi   +18 more
wiley   +1 more source

Assisted reproductive technique outcomes in hypogonadotropic hypogonadism women

Annals of Saudi Medicine, 2013
BACKGROUND AND OBJECTIVES: To evaluate the outcomes of using in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI cycle) techniques in hypogonadotropic hypogonadism (HH) women and comparing them to women with tubal factor infertility ...
Firouzeh Ghaffari, Arezoo Arabipoor, Narqes Bagheri Lankarani, Zhaleh Etminan, Ensieh Shahrokh Tehraninejad   +4 more
doaj   +1 more source