Results 161 to 170 of about 2,064,464 (296)

Modeling Diagnosis and Clinical Outcomes in Infertility Couples Considering Multiple Factors: A Retrospective Study. [PDF]

Int J Fertil Steril
Ghasemabadi A, Ghiasi Hafazi S, Effati S, Namakin K, Ahmadi Zand M, Ghamsary M.   +5 more
europepmc   +1 more source

CXCL10/SLC11A1 Axis Exacerbates Septic Liver Injury by Regulating Neutrophil Extracellular Traps Formation to Drive Macrophage Pro‑Inflammatory Polarization

Advanced Science, EarlyView.
In sepsis‐induced liver injury, marked neutrophil infiltration correlates with disease severity. Neutrophil SLC11A1 drives intracellular Fe2+ and ROS via the Fenton reaction, promoting NETs formation. Hepatocyte‐derived CXCL10 recruits neutrophils and activates the JAK/STAT1/SLC11A1 axis, enhancing NETs‐mediated inflammation.
Haiping Lin, Shicong Zheng, Pei Song, Jie Chang, Zewei Chen, Cang Li, Min Yu, Lude Wang, Shian Yu   +8 more
wiley   +1 more source

The causal relationship between serum metabolites and the development of infertility: A Mendelian randomization analysis. [PDF]

Medicine (Baltimore)
Zhang Y, Ma S, Wang T, Hu J, Gao Y, Yu W, Liu W, Wang Y, Zhang C, Sun Z.   +9 more
europepmc   +1 more source

Multi‐tissue Metabolic GWAS and Drought‐Responsive Multi‐omics Reveal the Genetic Basis of the Quinoa Metabolome

Advanced Science, EarlyView.
A multi‐omics framework combining multitissue genome‐wide association studies, metabolomics, transcriptomics, proteomics, and functional validation uncovers the genetic basis of specialized metabolism in quinoa. The study identifies hundreds of metabolite‐associated loci, prioritizes candidate genes for saponin, betalain, and flavonoid biosynthesis ...
Julia von Steimker, Elodie L. Rey, Clara Stanschewski, Regina Wendenburg, Annabella Klemmer, Markéta Macho, Venkatesh P. Thirumalaikumar, Noha O. Saber, Aleksandra Skirycz, Alisdair R. Fernie, Mark Tester, Saleh Alseekh   +11 more
wiley   +1 more source

Recurrent Pregnancy Loss: A Couple-Based Framework for Integrating Paternal Assessment. [PDF]

Biomedicines
Kritsotaki N, Diamantidis D, Koutlaki N, Machairiotis N, Tsikouras P.   +4 more
europepmc   +1 more source

8‐Oxoguanine Modified CircMTUS1 Drives PABPC1 Phase Separation to Promote Gastric Cancer Progression and Cisplatin Resistance via Autophagy

Advanced Science, EarlyView.
ABSTRACT Gastric cancer (GC) is a major global health concern, as its prevention and treatment remain significant challenges. The 8‐oxoguanine (o8G) modification of circRNAs, alongside their capacity to orchestrate liquid‐liquid phase separation (LLPS) and autophagy, plays a pivotal role in driving tumor progression and determining therapeutic outcomes.
Lei Peng, Lurong Li, Zhenghui Zhu, Chenyang Li, Huaiming Sang, Guoxin Zhang, Xuan Li, Yini Dang, Yuanyuan Li   +8 more
wiley   +1 more source

Coping with male factor infertility in India: A call for culturally contextualized biopsychosocial frameworks. [PDF]

Indian J Psychiatry
Pai P, Subramani D.
europepmc   +1 more source

The Efficiency of a Group-Specific Mandated Benefit Revisited: The Effect of Infertility Mandates [PDF]

This paper examines the labor market effects of state health insurance mandates that increase the cost of employing a demographically identifiable group.
Joanna N. Lahey
core  

EphB1‐Mediated Transient Blood‐Brain Barrier Opening Facilitates a Ferritin‐Based Nanotherapeutic for Alzheimer's Disease

Advanced Science, EarlyView.
We constructed a brain‐targeted AFn‐DPZ nanodrug delivery system and identified EphB1 as its receptor on the blood‐brain barrier (BBB). This system facilitates drug transport across the BBB and thereby ameliorates cognitive impairment in Alzheimer's disease.
Shilin Wen, Jingjing Gao, Zhixian Wang, Qiumin Ma, Xiao‐Ling Xu, Jianer Chen   +5 more
wiley   +1 more source

Health system level microcosting of infertility management in India: a retrospective cross-sectional study. [PDF]

BMJ Open
Vikani A, Patil P, Sharma D, Sachin O, Soman B, Bagepally BS, Tanwar R, Suri V, V R, M A, P R, Shrivastava D, Patel S, Prinja S, Joshi B.   +14 more
europepmc   +1 more source