Results 61 to 70 of about 172,040 (288)

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

open access: yesAdvanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi   +4 more
wiley   +1 more source

RhoA and Rac1 as Mechanotransduction Mediators in Colorectal Cancer

open access: yesAdvanced Biology, EarlyView.
Analysing RhoA and Rac1 protein levels in Colorectal cancer (CRC) samples under mechanical strain highlights their potential as diagnostic markers. Monitoring their activity could offer valuable insights into how cancer spreads, paving the way for new approaches to better understand and diagnose colorectal cancer.
Sharda Yadav   +5 more
wiley   +1 more source

Using a Supramolecular Approach to Engineer Modular Hydrogel Platforms for Culturing Protoplasts – from General Tissue Engineering to Cellular Agriculture

open access: yesAdvanced Biology, EarlyView.
Using supramolecular monomers, various hydrogel culture systems were formulated to culture protoplasts; including 2D, 2.5D, and 3D hydrogels. Depending on the culture platform, bioactive functionalization led to protoplast enlargement (2D and 2.5D) or plasmolysis (3D). This work shows the potential to modularly engineer synthetic platforms for cellular
Maritza M. Rovers   +3 more
wiley   +1 more source

Recent Advances in the Pharmacotherapy of Premature Ejaculation

open access: yesEuropean Medical Journal Urology, 2017
Premature ejaculation (PE) can be a very distressing condition and has been studied for many years. However, there exists confusion about the definition, incidence, and management of this condition.
Michael J. Butcher, Ege Can Serefoglu
doaj  

Global, regional and national burden of male infertility in 204 countries and territories between 1990 and 2019: an analysis of global burden of disease study

open access: yesBMC Public Health, 2023
Background Many countries and regions have experienced male fertility problems due to various influencing factors, especially in less developed countries. Unlike female infertility, male infertility receives insufficient attention.
Baoyi Huang   +4 more
doaj   +1 more source

Smoke, alcohol and drug addiction and male fertility [PDF]

open access: yes, 2018
In recent decades, the decline in human fertility has become increasingly more worrying: while therapeutic interventions might help, they are vexing for the couple and often burdened with high failure rates and costs.
DE ANGELIS, Cristina Concetta   +7 more
core   +1 more source

Modelling Atherosclerotic Plaque Cap Mechanics: Microcalcifications Reduce Mechanical Properties in Mesenchymal Stromal Cell‐Based Model

open access: yesAdvanced Biology, EarlyView.
This study develops a tissue‐engineered model of the atherosclerotic cap using human mesenchymal stromal cells (MSCs). After 2 weeks of culture to produce a collagenous matrix, a mineralizing medium induces microcalcifications over 4 weeks. These constructs, imaged with second harmonic generation microscopy, lead to reduced ultimate stress at rupture ...
Imke L. Jansen   +4 more
wiley   +1 more source

Male Infertility. Genetic Aspects

open access: yesPočki, 2014
This review presents evidence of some genetic factors of male infertility and the methods that can be used for its diagnosis. Among the genetic factors there are being distinguished the genetic apparatus changes at the level of gene (mutation ...
L.V. Tavokina
doaj   +1 more source

3D Bioprinting of Thick Adipose Tissues with Integrated Vascular Hierarchies

open access: yesAdvanced Functional Materials, Volume 35, Issue 12, March 18, 2025.
An advanced 3D bioprinting technique is used here to create thick adipose tissues with a central, vessel and extensive branching. The construct is made using alginate, gelatin and collagen‐based bioinks. Flow through the complex vessel network is demonstrated as well as its successful integration with a femoral artery following implantation in a rat ...
Idit Goldfracht   +5 more
wiley   +1 more source

Magnetic Field‐Assisted Conductive Nerve Guidance Conduit Enabling Peripheral Nerve Regeneration with Wireless Electrical Stimulation

open access: yesAdvanced Functional Materials, EarlyView.
This study introduces a conductive nerve guidance conduit integrated with wireless electrical stimulation through alternating magnetic fields, which induces currents and creates a supportive microenvironment for nerve regeneration. In vivo studies show that this approach significantly enhanced myelin restoration, gastrocnemius muscle regeneration ...
Shiheng Liu   +7 more
wiley   +1 more source

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