Results 231 to 240 of about 251,225 (348)

Population Pharmacokinetic and Exposure‐Response Analyses of Ibrutinib Combined With Bendamustine and Rituximab in Patients With Mantle Cell Lymphoma

open access: yesCPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Efficacy and safety of ibrutinib 560 mg once daily or placebo combined with bendamustine and rituximab (BR) were assessed in patients with mantle cell lymphoma in a randomized phase 3 study (SHINE). The analysis described explores the ibrutinib population pharmacokinetics (PK) and exposure‐response (E‐R) relationships of selected efficacy and ...
Per Olsson Gisleskog   +5 more
wiley   +1 more source

Flowing in History: Reflecting on Past Practices and Their Influence on the Health of Richmond River Catchment, New South Wales, Australia

open access: yesRiver Research and Applications, EarlyView.
ABSTRACT The Richmond River forms part of the coastal region of New South Wales (NSW) Australia, and is of great environmental, social, and economic importance. The history of the river reflects its role in providing the needs upon which human life depends—water, fertile soil, and food.
Amanda Reichelt‐Brushett   +3 more
wiley   +1 more source

Livestock Grazing and Dense Willow Shading Negatively Impact Instream Plant Growth

open access: yesRiver Research and Applications, EarlyView.
ABSTRACT Human impacts have degraded riverine environments worldwide. In south‐eastern Australia, livestock grazing and non‐native Salix spp. (Willow) infestations throughout riverine environments commonly degrade instream conditions on which instream plants rely. However, the effects of livestock grazing and Salix spp.
Kristen McNamara   +3 more
wiley   +1 more source

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