Results 91 to 100 of about 1,421,957 (340)

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

Molecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza, David James, Emma Creagh, James T. Murray   +3 more
wiley   +1 more source

Removal of Different Kinds of Heavy Metals by Novel PPG-nZVI Beads and Their Application in Simulated Stormwater Infiltration Facility

Applied Sciences, 2019
Polyvinyl alcohol and pumice synthetized guar gum-nanoscale zerovalent iron beads (PPG-nZVI beads) were synthesized, and their adsorption towards Pb2+, Cu2+, and Zn2+ ions was evaluated. The adsorption kinetics of metal ions was well fitted by the pseudo-
Xiaoran Zhang, Lei Yan, Junfeng Liu, Ziyang Zhang, Chaohong Tan   +4 more
doaj   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

The infiltration risk prediction models by logistic regression for ground-glass pulmonary nodules: a systematic review and meta-analysis

Frontiers in Oncology
MethodsCNKI, Wanfang, VIP, Sinomed, Pubmed, Web of Science, Embase, and other databases were searched. The retrieval time was from the establishment of the database to January 31, 2024.
Mengqian Li, Mengqian Li, Xiaomei Zhang, Yuxin Lai, Yunlong Sun, Tianshu Yang, Xinlei Tan   +6 more
doaj   +1 more source

On the simulation of infiltration- and saturation-excess runoff using radar-based rainfall estimates: Effects of algorithm uncertainty and pixel aggregation [PDF]

, 1998
The effects of uncertainty in radar-estimated precipitation input on simulated runoff generation from a medium-sized (100-km2) basin in northern Texas are investigated.
Gupta, HV, Sorooshian, S, Winchell, M
core   +1 more source

Persistent Infiltration and Impaired Response of Peripherally-Derived Monocytes after Traumatic Brain Injury in the Aged Brain. [PDF]

, 2018
Traumatic brain injury (TBI) is a leading cause for neurological disabilities world-wide. TBI occurs most frequently among the elderly population, and elderly TBI survivors suffer from reduced recovery and poorer quality of life. The effect of age on the
Chou, Austin, Krukowski, Karen, Morganti, Josh M, Riparip, Lara-Kirstie, Rosi, Susanna   +4 more
core   +3 more sources

The ACCEPTance of automation: refining circulating tumor cells enumeration for improved metastatic colorectal cancer prognosis

Molecular Oncology, EarlyView.
This study highlights the potential of automated enumeration using the ACCEPT software to refine circulating tumor cell (CTC) detection in metastatic colorectal cancer (mCRC). The automated method demonstrates improved accuracy and reduced variability compared to the manual approach.
Michela De Meo, Marco Siringo, Alessandro Vici, Ann Zeuner, Orietta Gandini, Paola Gazzaniga, Chiara Nicolazzo   +6 more
wiley   +1 more source

Influência da aplicação de águas residuárias de suinocultura na capacidade de infiltração de um solo Podzólico Vermelho-Amarelo Influence of swine wastewater application on the infiltration capacity of a Yellow-Red Podzol

Revista Brasileira de Engenharia Agrícola e Ambiental, 2000
Este trabalho foi conduzido na Área Experimental de Hidráulica, Irrigação e Drenagem do Departamento de Engenharia Agrícola da Universidade Federal de Viçosa, em Viçosa, MG, com o objetivo de se avaliar a influência de aplicações sucessivas de águas ...
Rubens Alves Oliveira, Paulo Luis Gonçalves Campelo, Antônio Teixeira Matos, Mauro Aparecido Martinez, Paulo Roberto Cecon   +4 more
doaj   +1 more source

Development and evaluation of hybrid aluminium matrix syntactic foams [PDF]

, 2013
A special class of metallic foams, the so called metal matrix syntactic foams was produced by pressure infiltration technique. Metal matrix syntactic foams consist of a light-weight metal matrix and a set of hollow spheres.
Májlinger, Kornél, Orbulov, Imre Norbert   +1 more
core