Results 91 to 100 of about 1,837,464 (375)

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Impact of overland flow on soil characteristics in Třebsín experimental plots

open access: yesSoil and Water Research, 2017
This paper describes the continuation of simulated outcomes from the plots No. 4 and No. 5 with two different soils, using the KINFIL model to assess the runoff from extreme rainfall. The KINFIL model is a physically-based, parameter-distributed 3D model
Hana BAČINOVÁ, Pavel KOVÁŘ
doaj   +1 more source

Evaluation of Beerkan Infiltration Method in Estimation of Saturated Hydraulic Conductivity of Soil [PDF]

open access: yesعلوم و مهندسی آبیاری, 2017
Determination of the field-saturated hydraulic conductivity can result in very high variability. So, analysis and simulation of hydrological processes such as runoff from rain requires a lot of data of field-saturated hydraulic conductivity even on a ...
Mahdi Keikha   +2 more
doaj   +1 more source

Improving predictive power of physically based rainfall-induced shallow landslide models: a probabilistic approach

open access: yes, 2014
Distributed models to forecast the spatial and temporal occurrence of rainfall-induced shallow landslides are based on deterministic laws. These models extend spatially the static stability models adopted in geotechnical engineering, and adopt an ...
Alvioli, M.   +5 more
core   +2 more sources

Biocompatibility and tissue regenerating capacity of crosslinked dermal sheep collagen [PDF]

open access: yes, 1994
The biocompatibility and tissue regenerating capacity of four crosslinked dermal sheep collagens (DSC) was studied. In vitro, the four DSC versions were found to be noncytotoxic or very low in cytoxicity.
Anselme   +36 more
core   +2 more sources

Landscape of immune cell infiltration in clear cell renal cell carcinoma to aid immunotherapy [PDF]

open access: gold, 2021
Dan Bai   +5 more
openalex   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Slurry infiltration tests for slurry shield tunnelling in saturated sand [PDF]

open access: yes, 2016
Tunnelling in saturated sand will cause excess pore pressures in the sand. This was the case during the construction of all tunnels in the Netherlands. This excess pore pressure influences the stability of the tunnel face.
Bezuijen, Adam, XU, T
core   +1 more source

The Miner's Dilemma [PDF]

open access: yes, 2014
An open distributed system can be secured by requiring participants to present proof of work and rewarding them for participation. The Bitcoin digital currency introduced this mechanism, which is adopted by almost all contemporary digital currencies and ...
Eyal, Ittay
core   +2 more sources

Effect of Water Infiltration, Injection Rate and Anisotropy on Hydraulic Fracturing Behavior of Granite

open access: yesRock Mechanics and Rock Engineering, 2019
Hydraulic fracturing tests on Pocheon granite cylinders at seven different injection rates varying from 1 to 100 mm3/s were conducted. They were compared with sleeve fracturing tests in which borehole was sleeved, and therefore, water infiltration ...
L. Zhuang   +4 more
semanticscholar   +1 more source

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