Results 71 to 80 of about 462,529 (288)
Morphology of rain water channelization in systematically varied model sandy soils [PDF]
, 2014 We visualize the formation of fingered flow in dry model sandy soils under different raining conditions using a quasi-2d experimental set-up, and systematically determine the impact of soil grain diameter and surface wetting property on water ...
Barrois, R. +4 more
core +6 more sources
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
ACI Avances en Ciencias e Ingenierías, 2013 Mountain ecosystems are receiving increasing attention due to their role in the regulation and supply of water for a growing human population, a pattern that is especially important in high altitude ecosystems of the northern Andes (páramo ...
Esteban Suárez R. +4 more
doaj +1 more source
Estrogen treatment decreases matrix metalloproteinase (MMP)-9 in autoimmune demyelinating disease through estrogen receptor alpha (ERalpha). [PDF]
, 2009 Matrix metalloproteinases (MMPs) have a crucial function in migration of inflammatory cells into the central nervous system (CNS). Levels of MMP-9 are elevated in multiple sclerosis (MS) and predict the occurrence of new active lesions on magnetic ...
Du, Sienmi +6 more
core +3 more sources
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
"Litter marks" around oil palm tree base indicating infiltration area of stemflow-induced water [PDF]
, 2014 The “litter marks” which has the dark color and shape like a circle was found around the oil palm tree base. These litter marks seem to be caused by the infiltration excess overland flow due to higher intensity of stemflow than the infiltration capacity ...
Abd. Rashid, Nor Suhada, Askari, Muhamad
core
Tangki Septik Dan Peresapannya Sebagai Sistem Pembuangan Air Kotor Di Permukiman Rumah Tinggal Keluarga [PDF]
, 2013 Every day, family residential neighborhoods discard the waste water that should be stored and processed. Most of waste water management system still does not meet the health requirements, it still use local waste water treatment systems (on-site) like ...
Linda Remy (3816304) +2 more
core +3 more sources
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
The Effects of Different Mulches on Temporal Changes on The Some Soil Physical Properties [PDF]
علوم و مهندسی آبیاری, 2016 Application of mulches not only affects the physical and chemical properties of soil, but improves infiltration maintenance. In this study, evaluated during four month, the effects of wheat straw, maize straw, sawdust, leaves and superab A200 on the soil
Zeynab Ahmadi Moghadam +2 more
doaj +1 more source