Results 41 to 50 of about 469,529 (269)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Infiltration rates: Effect of wetting agents in water on infiltration rates into soils
California Agriculture, 1954 Laboratory and field studies indicate there is little, if any, increase in the water infiltration rate into soils because of decreased surface tension of water treated with wetting agents.
O Lunt, M Huberty
openaire +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Jurnal Sumber Daya Air, 2022 Indonesia has 129 active volcanoes; therefore, the volcanic-related disasters risk is relatively high. Lahar flood is a secondary post-eruption disaster, which is triggered by the rainfall due to the movement of volcanic material by the runoff. After the
Joko Nugroho, Indratmo Soekarno, F Tata Yunita, Arno Adi Kuntoro
doaj +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Environmental and Climate Technologies, 2020 Building energy demand for heating and cooling has a complicated relationship with different environmental conditions surrounding the building sector. Many projects aiming to improve thermal performance in existing buildings in Jordan suggest that roof ...
Albatayneh Aiman +3 more
doaj +1 more source
International Journal of Engineering & Technology, 2020 The Northern Gaza Emergency Sewage Treatment (NGEST) is addressed as a promising water management intervention strategy to maintain the sustainability of groundwater aquifer in the Gaza Strip. This study assesses the current operational status of the north-ern Gaza wastewater infiltration basins located at NGEST project.
Mazen Abualtayef +3 more
openaire +2 more sources
Infiltration rate assessment of some major soils [PDF]
Irish Geography, 2003 An evaluation of the risk of overland flow is needed in order to minimise the risk of transferring pollutants from soil to rivers and lakes. The infiltration capacity of soil influences the occurrence of overland flow. The objectives of this study were to assess the infiltration capacity of some extensive soils in Ireland and also its spatial and ...
John Diamond, Thomas Shanley
openaire +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source