Results 51 to 60 of about 469,529 (269)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Estimation of Appropriate Infiltration Rate and the Effects of the Flowerbed Type Infiltration System

open access: yesJournal of the Korean Institute of Landscape Architecture, 2012
This study developed a flowerbed type infiltration system that could control the amount of runoff discharge under a certain level estimated its proper design infiltration rate, and analyzed the effects of its implementation. Analyzing the performance of infiltration system is the one of the essential processes that should be under review to predict its
Young-Hae Han, Tae-Goo Lee
openaire   +2 more sources

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Reconstruction of Water Infiltration Rate Reducibility in Response to Suspended Solid Characteristics Using Singular Spectrum Analysis: An Application to the Caspian Sea Coast of Nur, Iran

open access: yesHydrology, 2018
Drawing a distinction between the suspended solid size and concentration impacts on physical clogging process in the Managed Aquifer Recharge (MAR) systems has been fraught with difficulties.
Majid Taie Semiromi, Davood Ghasemian
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Investigation of the Effect of Compression Force on the Tensile Strength and Infiltration Rate of Pervious Concrete Blocks

open access: yesBuildings
Pervious concrete is widely used as a paving material. Pervious pavement is generally constructed by pouring fresh pervious concrete and compacting. However, it has some difficulties such as finishing and curing.
Ahmet Akkaya, İsmail Hakkı Çağatay
doaj   +1 more source

Artificial Recharge – Measurement of Soil Infiltration in Rožnov Pod Radhoštěm

open access: yesGeoScience Engineering, 2017
The purpose of this study is to evaluate the potential for infiltration in a study area – Rožnov pod Radhoštěm, the Czech Republic. The results are important for the future design of an artificial recharge structure as a method to store water underground
Chromíková Jitka   +4 more
doaj   +1 more source

Effect of Water Quality and Date Palm Biochar on Evaporation and Specific Hydrological Characteristics of Sandy Soil

open access: yesAgriculture, 2020
Experiments were conducted in a soil laboratory using transparent columns (5 and 40 cm in diameter and length, respectively) to evaluate the effects of water quality (i.e., fresh or saline water) with the addition of biochar on soil moisture ...
Arafat Alkhasha   +2 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

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