Results 71 to 80 of about 469,529 (269)

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

open access: yesFEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta   +7 more
wiley   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

Presenting and evaluating a new empirical relationship for estimating the rate of infiltration in trenches

open access: yesJournal of Groundwater Science and Engineering
Empirical formulas are indispensable tools in water engineering and hydraulic structure design. Derived from meticulous field observations, experiments, and diverse datasets, these formulas help to estimate water leakage in structures such as dams ...
Mojtaba Hassanpour   +2 more
doaj   +1 more source

Determining Infiltration Rate from Infiltration Measurement with Flooding Method by Turftech Infiltrometer

open access: yesCivil and Environmental Science, 2019
The density of the soil in this study estimate parameters with a dry bulk density. variation of soil density based on urban land us and then grouped into heavy, medium, and high-density soil. the rate of infiltration testing is performed by using turftech infiltrometer. and then analyzed with an infiltation horton modification models. the specification
D Noorvy Khaerudin   +2 more
openaire   +2 more sources

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Evaluation of a new experimental test procedure to more accurately determine the surface infiltration rate of permeable pavement systems

open access: yesUrban, Planning and Transport Research, 2014
Permeable pavements are specifically designed to promote the infiltration of stormwater through the paving surface in order to reduce run-off volumes and to improve water quality by removing sediment and other pollutants. However, research has shown that
Terry Lucke   +2 more
doaj   +1 more source

Adsorption of Phosphorus Infiltrating Andosol in Aso Caldera, Kumamoto

open access: yesJournal of Water and Environment Technology, 2020
High concentration (more than 1.0 mgP/L) of phosphorus was detected in groundwater in Aso caldera, Kumamoto. The fact indicates phosphorus can be transported by groundwater flows.
Daisuke Yumioka   +5 more
doaj   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

open access: yesAging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel   +4 more
wiley   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

open access: yesAging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho   +4 more
wiley   +1 more source

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