Results 101 to 110 of about 709,702 (295)
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Distinguishing Cartesian Products of Countable Graphs
Discussiones Mathematicae Graph Theory, 2017 The distinguishing number D(G) of a graph G is the minimum number of colors needed to color the vertices of G such that the coloring is preserved only by the trivial automorphism.
Estaji Ehsan +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Entropy of local homeomorphisms with applications to subshifts arising from infinite graphs. [PDF]
In this talk, we introduce topological entropy for dynamical systems generated by a single local homeomorphism (Deaconu-Renault systems). More precisely, we propose and compare entropy definitions via covers and via separated sets.
Gonçalves, Daniel
core
Edge-disjoint Linkages in Infinite Graphs [PDF]
, 2022 The main subject of this thesis is the infinite graph version of the weak linkage conjecture by Thomassen [24]. We first prove results about the structure of the lifting graph; Theorems 2.2.8, 2.2.24, and 2.3.1.
Assem Abd-AlQader Mahmoud, Amena
core
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
INCOMPLETE MARKETS IN INFINITE HORIZON: DEBT CONSTRAINTS VERSUS NODE PRICES [PDF]
, 1995 The general equilibrium model with incomplete markets is here extended to infinite horizon economies populated by a finite number of infinitely lived agents.
Monique Florenzano +3 more
core +2 more sources
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
Extremal infinite graph theory
Discrete Mathematics, 2011 We survey various aspects of infinite extremal graph theory and prove several new results. The lead role play the parameters connectivity and degree. This includes the end degree. Many open problems are suggested.
openaire +4 more sources
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source