Results 91 to 100 of about 17,894 (263)

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Extremal infinite graph theory

open access: yesDiscrete Mathematics, 2011
We survey various aspects of infinite extremal graph theory and prove several new results. The lead role play the parameters connectivity and degree. This includes the end degree. Many open problems are suggested.
openaire   +4 more sources

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Distance-Transitivity in Infinite Graphs

open access: yesJournal of Combinatorial Theory, Series B, 1994
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +2 more sources

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

A Note on Pseudofinite Acyclic Graphs

open access: yesИзвестия Иркутского государственного университета: Серия "Математика"
Acyclic graphs approximated by finite acyclic graphs are considered. It is proved that any countably categorical acyclic graph is smoothly approximable. An example of pseudofinite acyclic graph theory is given, which has an even, odd, and infinite number
N. D. Markhabatov, Ye. R. Baissalov
doaj   +1 more source

Centrosymmetric Graphs And A Lower Bound For Graph Energy Of Fullerenes

open access: yesDiscussiones Mathematicae Graph Theory, 2014
The energy of a molecular graph G is defined as the summation of the absolute values of the eigenvalues of adjacency matrix of a graph G. In this paper, an infinite class of fullerene graphs with 10n vertices, n ≥ 2, is considered.
Katona Gyula Y.   +2 more
doaj   +1 more source

Retracts of Infinite Hamming Graphs

open access: yesJournal of Combinatorial Theory, Series B, 1997
A Hamming graph is a Cartesian product of complete graphs. We show that (finite or infinite) quasi-median graphs, which are a generalization of median graphs, are exactly the retracts of Hamming graphs. This generalizes a result of \textit{H. J. Bandelt} [J.
openaire   +2 more sources

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

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