Results 71 to 80 of about 17,750 (263)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

An advance in infinite graph models for the analysis of transportation networks

open access: yesInternational Journal of Applied Mathematics and Computer Science, 2016
This paper extends to infinite graphs the most general extremal issues, which are problems of determining the maximum number of edges of a graph not containing a given subgraph.
Cera Martín, Fedriani Eugenio M.
doaj   +1 more source

Block circulant graphs and the graphs of critical pairs of crowns

open access: yesElectronic Journal of Graph Theory and Applications, 2019
In this paper, we provide a natural bijection between a special family of block circulant graphs and the graphs of critical pairs of the posets known as generalized crowns.
Rebecca E. Garcia   +3 more
doaj   +1 more source

Embeddings of infinite graphs

open access: yesJournal of Combinatorial Theory, Series B, 1988
Embeddings of infinite graphs in surfaces (not necessarily compact) without boundary are considered. Cellular embeddings are studied in details. Each rotation system of a locally finite graph G gives rise to a cellular embedding of G into some surface, and every cellular embedding with all 2-cells of finite size can be obtained in this way.
openaire   +2 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

The mincut graph of a graph

open access: yesElectronic Journal of Graph Theory and Applications
In this paper we introduce an intersection graph of a graph G, with vertex set the minimum edge-cuts of G. We find the minimum cut-set graphs of some well-known families of graphs and study the mincut graph as a graph operator.
Christo Kriel, Eunice Mphako-Banda
doaj   +1 more source

Isoscattering strings of concatenating graphs and networks

open access: yesScientific Reports, 2021
We identify and investigate isoscattering strings of concatenating quantum graphs possessing n units and 2n infinite external leads. We give an insight into the principles of designing large graphs and networks for which the isoscattering properties are ...
Michał Ławniczak   +3 more
doaj   +1 more source

Fragments and Automorphisms of Infinite Graphs

open access: yesEuropean Journal of Combinatorics, 1984
The authors investigate the structure of infinite graphs \(\Gamma\) with \(\kappa_{\infty}(\Gamma)
Heinz Adolf Jung, Mark E. Watkins
openaire   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Infinite graphs—A survey

open access: yesJournal of Combinatorial Theory, 1967
AbstractThis expository article describes work which has been done on various problems involving infinite graphs, mentioning also a few unsolved problems or suggestions for future investigation.
openaire   +2 more sources

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