Results 111 to 120 of about 3,935,207 (294)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Karush-Kuhn-Tucker Types Optimality Conditions for Non-Smooth Semi-Infinite Vector Optimization Problems

open access: yesJournal of Mathematical Extension, 2015
In this paper we establish necessary and sufficient optimality conditions for a nondifferenriable, nonconvex semi-infinite vector optimization problem involving locally Lipschitz functions, whose constraints are required to depend continuously on an ...
N. Kanzi∗
doaj  

Optimisation of a Third Order System

open access: yesMeasurement + Control, 1971
A general algebraic method of optimising a third order system is presented. The method consists of extending Pontryagin's Maximum Principle to the infinite interval case and reducing the characteristic two point boundary value problem to that of the ...
L. H. Lees
doaj   +1 more source

Chain Conditions for Subgroups of Infinite Order or Index

open access: yesJournal of Algebra, 2002
Various weakened forms of the maximal condition on subgroups max and the minimal condition on subgroups min have been proposed, the best known being the weak maximal and minimal conditions of \textit{D. I. Zajtsev} [Dokl. Akad. Nauk. SSSR 178, 780-782 (1968; Zbl 0167.28803)].
openaire   +2 more sources

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

On the homotopy index for infinite-dimensional semiflows [PDF]

open access: yesTransactions of the American Mathematical Society, 1982
In this paper we consider semiflows whose solution operator is eventually a conditional α \alpha
openaire   +2 more sources

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

Evaluating Large Language Models in Code Generation: INFINITE Methodology for Defining the Inference Index

open access: yesApplied Sciences
This study introduces a new methodology for an Inference Index (InI) called the Inference Index In Testing Model Effectiveness methodology (INFINITE), aiming to evaluate the performance of Large Language Models (LLMs) in code generation tasks.
Nicholas Christakis, Dimitris Drikakis
doaj   +1 more source

Eccentric Connectivity Index of t-Polyacenic Nanotubes

open access: yesAdvances in Materials Science and Engineering, 2019
The eccentric connectivity index ECI is a chemical structure descriptor that is currently being used for the modeling of biological activities of a chemical compound.
Jia-Bao Liu   +3 more
doaj   +1 more source

Unions of chains of subgroups of a topologucal group

open access: yesApplied General Topology, 2001
We consider the following problem: If a topological group G is the union of an increasing chain of subgroups and certain cardinal invariants of the subgroups in the chain are known, what can be said about G?
Yolanda Torres Falcón
doaj   +1 more source

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