Results 81 to 90 of about 9,803,245 (284)

An Integrated Oxygen‐Supplying Device and Predictive Multiphysics Model for Extended Ambient Transport of Insulin‐Producing Cells

Advanced Functional Materials, EarlyView.
Cell therapies typically rely on cold‐chain logistics and cryopreservation, limiting access and compromising cell quality. Here, a dual‐chamber device separates an oxygen‐supplying chamber from a hyaluronic acid cargo chamber, sustaining oxygen delivery for over 70 h and enabling ambient‐temperature shipment.
Daniel A. Domingo‐Lopez, Ruth Tarpey, Benjamin Brennan, Bryan D. Boyle, Amir M. Alsharabasy, Abhik Mallick, Gabriella Bellavia, Abhay Pandit, Garry P. Duffy, Ruth E. Levey   +9 more
wiley   +1 more source

Infinitely many solutions for hemivariational inequalities involving the fractional Laplacian

Journal of Inequalities and Applications, 2019
In the paper, we consider the following hemivariational inequality problem involving the fractional Laplacian: {(−Δ)su+λu∈α(x)∂F(x,u)x∈Ω,u=0x∈RN∖Ω, $$ \textstyle\begin{cases} (-\Delta )^{s}u+\lambda u\in \alpha (x) \partial F(x,u) & x \in \varOmega ...
Lijing Xi, Yuying Zhou
doaj   +1 more source

A Holistic Platform Approach for Developing Robust Pulmonary mRNA Delivery: Integrating Novel Phenolic Acid‐Derived Ionizable Lipids and Device Engineering

Advanced Functional Materials, EarlyView.
An integrated pulmonary mRNA delivery platform combining novel biodegradable syringic acid‐derived ionizable lipids, design‐of‐experiments formulation optimization, and vibrating‐mesh nebulizer engineering enabled stable aerosolization and efficient lung delivery.
Neha Kaushal, Younan Ma, Asad Khanmohammed, Dipen Parande, Hanming Zhang, Saket Dolare, Juliet Chen, Apiwat Wangweerawong, Saswata Karmakar, Hongfeng Deng, Frank Koppenhagen, Shraddha Sharma, Eric Reyes, Sherry He, Lianne Boeglin, Caroline Woo, Azadeh Paksa, Ayed Allawzi, Anusha Dias, Gregory Troiano, Shrirang Karve, Frank DeRosa   +21 more
wiley   +1 more source

A Systematic Study of GelMA‐Carbopol Bioinks for High‐Fidelity Extrusion 3D Bioprinting at Physiological Temperatures

Advanced Healthcare Materials, EarlyView.
Gonzalez Martinez and collaborators develop a strategy to formulate high performance GelMA‐based bioinks with low solids contents. The resulting bioinks enable 3D bioprinting at 37 °C of high‐fidelity structures with tunable mechanical properties that support high cell viability and function.
David A. González‐Martínez, Aidee V. Arizpe Tafoya, Eduardo González‐Martínez, Mabel Barreiro Carpio, Laura Daniela Serrano Andrade, Christopher T. N. Chow, Mohammadhossein Dabaghi, Jeremy A. Hirota, Jose M. Moran‐Mirabal   +8 more
wiley   +1 more source

Infinitely many solutions for non-local problems with broken symmetry

Advances in Nonlinear Analysis, 2018
The aim of this paper is to investigate the existence of solutions of the non-local elliptic ...
Bartolo Rossella, De Nápoli Pablo L., Salvatore Addolorata   +2 more
doaj   +1 more source

Engineering Concentration‐Dependent Intravitreal Mobility via Cyclic Arginine‐Enriched Nanocarrier Surface Modification: In Vivo Proof‐of‐Concept in a Porcine Large Animal Model

Advanced Healthcare Materials, EarlyView.
In this study, Hammer et al. highlight cyclic‐arginine surface engineering as a highly biocompatible, controllable, and concentration‐dependent regulator of intravitreal nanoparticle mobility in vivo in a translational large animal model. The cyclic arginine surface‐modification supports the development of next‐generation biomaterials for long‐acting ...
Maximilian Hammer, Bryan Calder Ackermann, Anna Stoß, Niklas Junker, Ludwig Geisweid, Sabrina Wohlfart, Jonathan Herth, Simon William Pohl, Manuel Ben Böhmann, André Schulz, Victor Aristide Augustin, Gerd Uwe Auffarth, Philipp Uhl   +12 more
wiley   +1 more source

Infinitely many solutions for a fourth-order boundary-value problem

Electronic Journal of Differential Equations, 2012
In this article we consider the existence of infinitely many solutions to the fourth-order boundary-value problem $$displaylines{ u^{iv}+alpha u''+eta(x) u=lambda f(x,u)+h(u),quad xin]0,1[cr u(0)=u(1)=0,cr u''(0)=u''(1)=0,.
Seyyed Mohsen Khalkhali, Shapour Heidarkhani, Abdolrahman Razani   +2 more
doaj  

Water‐Soluble, Enzyme‐Degradable, and Hydrolyzable STAR Particles for Enhanced Drug Delivery to Skin

Advanced Healthcare Materials, EarlyView.
Biodegradable polymer STAR particles fabricated from water‐soluble, enzyme‐degradable, and hydrolyzable materials significantly enhance intradermal drug delivery. By replacing conventional non‐biodegradable materials, these STAR particles address environmental and safety concerns while expanding the potential of skin‐based drug delivery technologies ...
Aydin Sadeqi, Gülçin Arslan Azizoğlu, Mark R. Prausnitz   +2 more
wiley   +1 more source

INFINITELY MANY SOLUTIONS FOR A CLASS OF SUBLINEAR SCHRÖDINGER EQUATIONS

Taiwanese Journal of Mathematics, 2015
In this paper, we deal with the existence of infinitely many solutions for a class of sublinear Schrodinger equation $$ \left\{ \begin{array}{ll} -\triangle u+V(x)u=f(x, u), \ \ \ \ x\in {\mathbb{R}}^{N},\\ u\in H^{1}({\mathbb{R}}^{N}). \end{array} \right. $$ Under the assumptions that $\inf_{{\mathbb{R}}^{N}}V(x) >0$ and $f(x,
Chen, Jing, Tang, X. H.
openaire   +2 more sources

Infinitely many positive solutions for a p(x)-Kirchhoff-type equation [PDF]

, 2009
This paper is concerned with the existence of infinitely many positive solutions to a class of p(x)-Kirchhoff-type problem. By means of a direct variational approach and the theory of the variable exponent Sobolev spaces, we establish the existence of ...
Dai, Guowei, Guowei Dai, Duchao Liu, Liu, Duchao   +3 more
core   +1 more source