Results 31 to 40 of about 3,477 (115)

Toll‐like receptor‐ligand induced thymic stromal lymphopoietin expression in primary equine keratinocytes

Veterinary Dermatology, Volume 31, Issue 2, Page 154-e30, April 2020., 2020
Background Thymic stromal lymphopoietin (TSLP) plays a key role in the development of allergic inflammation. Little is known about possible triggers of equine TSLP expression. Hypothesis To investigate TSLP expression in equine insect bite hypersensitivity (IBH) skin lesions.
Iva Cvitas, Arnaud Galichet, Shui Chu Ling, Eliane J. Müller, Eliane Marti   +4 more
wiley   +1 more source

Modulation of Dendritic Cell Apoptosis and CD8+ Cytotoxicity by Histamine: Role of Protein Kinase C

Mediators of Inflammation, 2017
Dendritic cells (DC) are able to present extracellular antigens associated with the molecules of the major histocompatibility complex class I. In a previous work, we demonstrated that the histamine (HIS), acting through H1/H4 receptors, increases the ...
Julieta Alcain, Enrique Podaza, María Soledad Gori, Gabriela Salamone, Mónica Vermeulen   +4 more
doaj   +1 more source

P2X7 receptor induces mitochondrial failure in monocytes and compromises NLRP3 inflammasome activation during sepsis

Nature Communications, 2019
Systemic sepsis is a potentially life-threatening illness and immunocompromised individuals are especially vulnerable. Here, using a cohort of patients with intra-abdominal origin sepsis, the authors show an important role for the NLRP3 inflammasome in ...
Juan José Martínez-García, Helios Martínez-Banaclocha, Diego Angosto-Bazarra, Carlos de Torre-Minguela, Alberto Baroja-Mazo, Cristina Alarcón-Vila, Laura Martínez-Alarcón, Joaquín Amores-Iniesta, Fátima Martín-Sánchez, Giovanni A. Ercole, Carlos M. Martínez, Ada González-Lisorge, José Fernández-Pacheco, Piedad Martínez-Gil, Sahil Adriouch, Friedrich Koch-Nolte, Juan Luján, Francisco Acosta-Villegas, Pascual Parrilla, Carlos García-Palenciano, Pablo Pelegrin   +20 more
doaj   +1 more source

Granulocitos de baja densidad: Un nuevo marcador de deterioro óseo en pacientes en diálisis peritoneal

Revista de Osteoporosis y Metabolismo Mineral, 2022
Objetivo: En enfermos renales, la enfermedad ósea-metabólica, la inflamación sistémica y la malnutrición exacerban el riesgo de calcificación vascular (CV) y la morbimortalidad.
Ulloa-Clavijo C, Martín-Vírgala J, Gómez-Alonso C, Fernández-Mariño B, Rodríguez-Carrio J, Carrillo-López N, Sobrino-Díaz L, Rodríguez C, Rodríguez-García M, Suarez A, Dusso A   +10 more
doaj   +1 more source

Tratamiento con tocilizumab en amiloidosis AA: informe de casos y revisión de la literatura

Revista del Hospital Italiano de Buenos Aires, 2021
Introducción: la amiloidosis AA puede ser una complicación de ciertos trastornos inflamatorios crónicos, aunque entre el 21% y 50% puede ser idiopática. No existe un tratamiento específico. El tocilizumab, dirigido contra el receptor de IL-6 y orientado
María A. Aguirre, Mariana Vaena, Marcelina Carretero, Elsa M. Nucifora, María S. Sáez, Patricia Sorroche, Akemi Zanella, María L. Posadas-Martínez   +7 more
doaj   +1 more source

Hydrocortisone Aceponate for Chronic Otitis: Long‐Term Efficacy

Veterinary Dermatology, EarlyView.
Effective management of otitis externa (OE) requires addressing all contributing factors to prevent chronicity and recurrence. Evidence on the long‐term efficacy of topical corticosteroids in preventing recurrence and secondary infections remains limited. This retrospective noncontrolled study evaluated the efficacy of hydrocortisone aceponate (HCA) in
C. Lorente‐Méndez, D. Alonso‐Miguel
wiley   +1 more source

Scorpion Venom and the Inflammatory Response

Mediators of Inflammation, 2010
Scorpion venoms consist of a complex of several toxins that exhibit a wide range of biological properties and actions, as well as chemical compositions, toxicity, and pharmacokinetic and pharmacodynamic characteristics.
Vera L. Petricevich
doaj   +1 more source

Dermoscopic evaluation of normal canine skin with a handheld dermoscope

Veterinary Dermatology, Volume 36, Issue 5, Page 593-601, October 2025.
Background – Dermoscopy is a noninvasive diagnostic tool that provides a magnified view of skin structures. While dermoscopy is described for certain canine dermatological diseases, large‐scale studies evaluating normal skin are lacking. Hypothesis/Objective – This study aimed to correlate dermoscopic findings with histopathological results in healthy ...
Rachael Loek, David Gardiner, George Moore, Ashfaq Marghoob, Carine Laporte   +4 more
wiley   +1 more source

Evaluation of filaggrin 2 expression in dogs with atopic dermatitis before and after oclacitinib maleate administration

Veterinary Dermatology, Volume 36, Issue 4, Page 453-461, August 2025.
Background – Canine atopic dermatitis (cAD) is a chronic, inflammatory, multifactorial and pruritic disease. The presence of skin barrier impairment (e.g. filaggrin alterations), along with abnormal immune responses, can negatively impact cutaneous barrier function.
Wendie Roldan Villalobos, Tássia Ferreira, Fernanda Borek, Domenico Santoro, Lluis Ferrer, Marconi Farias   +5 more
wiley   +1 more source

C‐reactive protein (CRP) in high altitude Bolivian peri‐urban adolescents varies by adiposity, current illness, height, socioeconomic status, sex, and menarcheal status: The potential benefits and costs of adipose reserves in arduous environments

American Journal of Human Biology, Volume 36, Issue 9, September 2024.
Abstract Objectives In non‐industrialized and low‐income populations, adipose stores can serve as a valuable buffer against harsh conditions such as seasonal food scarcity. However, these reserves may incur costs due to adipocytes' production of pro‐inflammatory cytokines; inflammation is associated with increased risk for cardiometabolic diseases ...
Virginia J. Vitzthum, Jonathan Thornburg, Thomas W. McDade, Kathryn A. Hicks, Aaron Miller, Emily M. Chester, Baileigh Goodlett, Esperanza Caceres, Hilde Spielvogel   +8 more
wiley   +1 more source