Results 11 to 20 of about 28,169 (151)
La inflamación es la respuesta de su cuerpo a las lesiones e infecciones – así es como su sistema inmunológico ayuda a protegerlo de cualquier daño. Por el contrario, la inflamación crónica contribuye a muchas enfermedades, como enfermedades cardíacas ...
Daniela Rivero-Mendoza, Wendy J. Dahl
doaj +2 more sources
Background – While the clinical features were described recently, the histopathological characterisation of trunk‐dominant canine pemphigus foliaceus (PF) is lacking, and whether it differs from classic facial or insecticide‐triggered PF is unknown. Hypothesis/Objectives – This study describes the histopathological findings of trunk‐dominant PF, and ...
Natalie Katharina Yvonne Gedon +6 more
wiley +1 more source
GSK3β Inhibition Prevents Macrophage Reprogramming by High-Dose Methotrexate
Methotrexate (MTX) is an antifolate drug used as a chemotherapeutic agent for acute lymphoblastic leukemia, where MTX improves patients’ prognosis. Macrophage reprogramming is being increasingly assessed as an antitumor therapeutic strategy. However, and
Israel Ríos +9 more
doaj +1 more source
Background – The caninised monoclonal antibody lokivetmab (LKV), directed at interleukin (IL)‐31, is very effective at controlling pruritus in most dogs with atopic dermatitis (AD). However, evidence exists that IL‐31 is not required for the induction of acute allergic skin inflammation, which might explain why this treatment is less efficacious in ...
Chie Tamamoto‐Mochizuki +4 more
wiley +1 more source
Conditioned serum in vitro treatment of chondrocyte pellets and osteoarthritic explants
Abstract Background Autologous conditioned serum (ACS) is used to treat osteoarthritis in horses, although its effects are not fully investigated. Objectives To investigate the effects of equine serum and conditioned serum on chondrocytes stimulated with interleukin (IL)‐1β and cartilage explants with mild osteoarthritis.
Maria Löfgren +8 more
wiley +1 more source
La quinasa Fgr como diana terapéutica en inflamación cardiaca [PDF]
Las enfermedades cardiovasculares son la causa más común de mortalidad a nivel mundial, afectando aproximadamente al 32% de la población global [1].
Enríquez Domínguez, José Antonio +2 more
core +4 more sources
The expression of YWHAZ and NDRG1 predicts aggressive outcome in human prostate cancer
Using integrative tissue-omics, Lage-Vickers, Bizzotto et al. classify prostate cancer patients into high YWHAZ and NDRG1 expression subgroups that correlate with a high and intermediate risk of disease progression.
Sofia Lage-Vickers +12 more
doaj +1 more source
Background and AimsGM-CSF-dependent macrophage polarization has been demonstrated in rheumatoid arthritis (RA). Our aim was to seek diagnostic/prognostic biomarkers for undifferentiated arthritis (UA) by analyzing GM-CSF expression and source, macrophage
Sara Fuentelsaz-Romero +9 more
doaj +1 more source
The inflammatory tumor microenvironment is a fertile niche accelerating prostate cancer (PCa). We have reported that heme-oxygenase (HO-1) had a strong anti-tumoral effect in PCa.
Emiliano Ortiz +8 more
doaj +1 more source
Mast Cells in Immune-Mediated Cholangitis and Cholangiocarcinoma
Cholestasis, which is impaired bile flow from the liver into the intestine, can be caused by cholangitis and/or bile duct obstruction. Cholangitis can arise from bacterial infections and cholelithiasis, however, immune-mediated cholangitis in primary ...
Marisol I. González +4 more
doaj +1 more source

