Results 71 to 80 of about 2,834,842 (317)
Background Irritable Bowel Syndrome (IBS) is a widespread disease with variable symptoms that have an important impact on the quality of life. Despite the prevalence of IBS, its etiology and pathophysiology are still to be fully understood, but immune ...
Mattia Cappelletti +6 more
doaj +1 more source
Determining Parental Factors for Clinical Trial Attrition in Pediatric Acute Lymphoblastic Leukemia
ABSTRACT Background/Objectives Despite high enrollment rates on Children's Oncology Group (COG) protocols, attrition after initial consent is challenging, introducing bias and prolonging trial completion. While adult oncology literature has identified predictors of withdrawal, little is known about caregiver decision‐making for child participation in ...
Kimberly L. Stathas +3 more
wiley +1 more source
Nutrient excess results in systemic inflammation in diabetes contributing to insulin resistance, dyslipidaemia and increased cardiovascular risk. GLP-1 agonists and DPP-4 inhibitors, which are now well accepted therapies for diabetes may play a unique role in modulating this inflammatory process.
openaire +3 more sources
Local kappa opioid receptor activation decreases temporomandibular joint inflammation [PDF]
In an attempt to decrease central side effects associated with the use of opioids, some strategies have been developed by targeting peripheral opioid receptors.
Melo, Vilma +7 more
core +1 more source
A Bibliometric Analysis of Publications in Uremic Toxins From 1991 to 2024
ABSTRACT Background Uremic toxins are a growing area of research in nephrology, with significant implications in the progression and treatment of chronic kidney disease (CKD) and the management of end‐stage kidney disease (ESKD). This bibliometric analysis aims to evaluate the global research trends, key contributors, and the impact of publications in ...
Yuh‐Shan Ho +7 more
wiley +1 more source
ES-62 protects against collagen-induced arthritis by resetting interleukin-22 towards resolution of inflammation in the joints [PDF]
Objective. The parasitic worm–derived immunomodulator ES-62 protects against disease in the mouse collagen-induced arthritis (CIA) model of rheumatoid arthritis (RA) by suppressing pathogenic interleukin-17 (IL-17) responses. The Th17 associated cytokine
Al-Riyami, Lamyaa +12 more
core +1 more source
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye +33 more
wiley +1 more source
Balanced regulation of inflammation and resolution [PDF]
The immune system relies on a delicate balance of interconnected inflammatory and resolution pathways to maintain tissue homeostasis. Neutrophils and M1 macrophages play a pivotal role in acute inflammation by combating invading pathogens and clearing ...
Tang, Yidan
core
Coupled cell networks are target cells of inflammation, which can spread between different body organs and develop into systemic chronic inflammation [Elektronisk resurs] [PDF]
Several organs in the body comprise cells coupled into networks. These cells have in common that they are excitable but do not express action potentials.
Sveriges lantbruksuniversitet. +1 more
core +1 more source
Counteracting the effects of TNF receptor‐1 has therapeutic potential in Alzheimer's disease
Alzheimer's disease (AD) is the most common form of dementia, and neuroinflammation is an important hallmark of the pathogenesis. Tumor necrosis factor (TNF) might be detrimental in AD, though the results coming from clinical trials on anti‐TNF ...
Sophie Steeland +14 more
doaj +1 more source

