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Lipid Mediators in Inflammation [PDF]

open access: yesMicrobiology Spectrum, 2016
Lipids are potent signaling molecules that regulate a multitude of cellular responses, including cell growth and death and inflammation/infection, via receptor-mediated pathways. Derived from polyunsaturated fatty acids (PUFAs), such as arachidonic acid (
Bennett, M, Gilroy, DW
core   +6 more sources

The systemic-level repercussions of cancer-associated inflammation mediators produced in the tumor microenvironment. [PDF]

open access: yesFront Endocrinol (Lausanne), 2022
The tumor microenvironment is a dynamic, complex, and redundant network of interactions between tumor, immune, and stromal cells. In this intricate environment, cells communicate through membrane–membrane, ligand–receptor, exosome, soluble factors, and ...
Aguilar-Cazares D   +7 more
europepmc   +2 more sources

Are Oxidative Stress and Inflammation Mediators of Bone Loss Due to Estrogen Deficiency? A Review of Current Evidence. [PDF]

open access: yesEndocr Metab Immune Disord Drug Targets, 2020
Osteoporosis is one of the major health issues associated with menopause-related estrogen deficiency. Various reports suggest that the hormonal changes related to menopausal transition may lead to the derangement of redox homeostasis and ultimately ...
Mohamad NV, Ima-Nirwana S, Chin KY.
europepmc   +2 more sources

Serum T2-High Inflammation Mediators in Eosinophilic COPD [PDF]

open access: yesBiomolecules
Eosinophils are central inflammatory cells in asthma; however, a portion of patients with chronic obstructive pulmonary disease (COPD) have blood or sputum eosinophilia, a condition termed eosinophilic COPD (eCOPD), which may contribute to the ...
Andrius Januskevicius   +5 more
doaj   +2 more sources

Genome Wide Transcriptome Analysis of Dendritic Cells Identifies Genes with Altered Expression in Psoriasis [PDF]

open access: yes, 2013
Activation of dendritic cells by different pathogens induces the secretion of proinflammatory mediators resulting in local inflammation. Importantly, innate immunity must be properly controlled, as its continuous activation leads to the development of ...
Filkor, Katalin   +6 more
core   +22 more sources

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