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Lipid Mediators in Inflammation [PDF]
Microbiology Spectrum, 2016 Lipids are potent signaling molecules that regulate a multitude of cellular responses, including cell growth and death and inflammation/infection, via receptor-mediated pathways. Derived from polyunsaturated fatty acids (PUFAs), such as arachidonic acid (
Bennett, M, Gilroy, DW
core +7 more sources
Sequential release of cytokines, lipid mediators and nitric oxide in experimental colitis [PDF]
Mediators of Inflammation, 1995 The object of this study was to establish whether different pro- and anti-inflammatory mediators were formed in colonic tissue from experimental colitis depending on the course of the disease.
A. P. M. van Dijk +3 more
doaj +4 more sources
Quantifying the relevance of different mediators in the human immune cell network [PDF]
Bioinformatics. 2005 Apr 15;21(8):1639-43. Epub 2004 Dec 21., 2004 Immune cells coordinate their efforts for the correct and efficient functioning of the immune system (IS). Each cell type plays a distinct role and communicates with other cell types through mediators such as cytokines, chemokines and hormones, among others, that are crucial for the functioning of the IS and its fine tuning.
Castellani, Gastone C. +6 more
arxiv +3 more sources
The Role of Inflammatory Mediators in the Pathogenesis of Alzheimer’s Disease [PDF]
Sultan Qaboos University Medical Journal, 2015 Alzheimer’s disease (AD), a neurodegenerative disorder associated with advanced age, is the most common cause of dementia globally. AD is characterised by cognitive dysfunction, deposition of amyloid plaques, neurofibrillary tangles and neuro ...
Gholamreza Azizi +5 more
doaj +6 more sources
Distinct etiology of chronic inflammation – implications on degenerative diseases and cancer therapy [PDF]
Frontiers in ImmunologyAcute inflammation is elicited by lipid and protein mediators in defense of the host following sterile or pathogen-driven injury. A common refrain is that chronic inflammation is a result of incomplete resolution of acute inflammation and behind the ...
Krishna Rao Maddipati
doaj +2 more sources
Mediators of Inflammation in Pulmonary Diseases [PDF]
Mediators of Inflammation, 2015 Inflammation is supposed to play a great role in the pathogenesis of the most common diseases of the respiratory system. In Chronic Obstructive Pulmonary Disease (COPD), which is a major cause of morbidity and mortality all around the world, smoking mainly causes the initiation of the inflammatory process that leads to an impaired respiratory function.
Kostas Spiropoulos +4 more
doaj +5 more sources
Efferocytes release extracellular vesicles to resolve inflammation and tissue injury via prosaposin-GPR37 signaling [PDF]
Cell Reports, 2023 Summary: Macrophages release soluble mediators following efferocytic clearance of apoptotic cells to facilitate intercellular communication and promote the resolution of inflammation. However, whether inflammation resolution is modulated by extracellular
Purbasha Bhattacharya +8 more
doaj +3 more sources
Serum T2-High Inflammation Mediators in Eosinophilic COPD [PDF]
BiomoleculesEosinophils are central inflammatory cells in asthma; however, a portion of patients with chronic obstructive pulmonary disease (COPD) have blood or sputum eosinophilia, a condition termed eosinophilic COPD (eCOPD), which may contribute to the ...
Andrius Januskevicius +5 more
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Gaseous mediators in resolution of inflammation
Seminars in Immunology, 2015 There are numerous gaseous substances that can act as signaling molecules, but the best characterized of these are nitric oxide, hydrogen sulfide and carbon monoxide. Each has been shown to play important roles in many physiological and pathophysiological processes.
Wallace, John L +3 more
openaire +6 more sources
Vision for Mediators of Inflammation [PDF]
Mediators of Inflammation, 2020 Anshu Agrawal
doaj +3 more sources