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Are Oxidative Stress and Inflammation Mediators of Bone Loss Due to Estrogen Deficiency? A Review of Current Evidence. [PDF]
Endocr Metab Immune Disord Drug Targets, 2020 Osteoporosis is one of the major health issues associated with menopause-related estrogen deficiency. Various reports suggest that the hormonal changes related to menopausal transition may lead to the derangement of redox homeostasis and ultimately ...
Mohamad NV, Ima-Nirwana S, Chin KY.
europepmc +2 more sources
Lipid Mediators in Inflammation [PDF]
Microbiology Spectrum, 2016 ABSTRACTLipids are potent signaling molecules that regulate a multitude of cellular responses, including cell growth and death and inflammation/infection, via receptor-mediated pathways. Derived from polyunsaturated fatty acids (PUFAs), such as arachidonic acid (AA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA), each lipid displays ...
Bennett, M, Gilroy, DW
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Mediators of Inflammation in Pulmonary Diseases [PDF]
Mediators of Inflammation, 2015 Inflammation is supposed to play a great role in the pathogenesis of the most common diseases of the respiratory system. In Chronic Obstructive Pulmonary Disease (COPD), which is a major cause of morbidity and mortality all around the world, smoking mainly causes the initiation of the inflammatory process that leads to an impaired respiratory function.
Kostas Spiropoulos +4 more
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Serum T2-High Inflammation Mediators in Eosinophilic COPD [PDF]
BiomoleculesEosinophils are central inflammatory cells in asthma; however, a portion of patients with chronic obstructive pulmonary disease (COPD) have blood or sputum eosinophilia, a condition termed eosinophilic COPD (eCOPD), which may contribute to the ...
Andrius Januskevicius +5 more
doaj +2 more sources
Vision for Mediators of Inflammation [PDF]
Mediators of Inflammation, 2020 Anshu Agrawal
doaj +4 more sources
Gaseous mediators in resolution of inflammation
Seminars in Immunology, 2015 There are numerous gaseous substances that can act as signaling molecules, but the best characterized of these are nitric oxide, hydrogen sulfide and carbon monoxide. Each has been shown to play important roles in many physiological and pathophysiological processes.
Wallace, John L +3 more
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Mediators of Inflammation: Inflammation in Cancer, Chronic Diseases, and Wound Healing
Mediators of Inflammation, 2015 Chronic diseases and conditions, such as kidney and liver failure, cancers, and diabetes, are the leading causes of morbidity and mortality, and, according to the data published by the World Health Organization [1], these diseases caused 38 million ...
Caigan Du +4 more
doaj +2 more sources
Mediators of inflammation [PDF]
Current Opinion in Immunology, 1997 Therapeutic studies and genetically engineered animals have elucidated the inflammatory roles of cytokines and chemokines in autoimmune disease. Most unexpected has been a continuum of recent evidence demonstrating that inflammatory mediators are crucial in lymphoid organ development, thus suggesting that these hitherto unrelated processes have common ...
Carolyn A. Cuff +2 more
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Pro-resolving lipid mediators: regulators of inflammation, metabolism and kidney function
Nature Reviews Nephrology, 2021 Obesity, diabetes mellitus, hypertension and cardiovascular disease are risk factors for chronic kidney disease (CKD) and kidney failure. Chronic, low-grade inflammation is recognized as a major pathogenic mechanism that underlies the association between
E. Brennan +3 more
semanticscholar +1 more source
Mediators of liver inflammation and carcinogenesis [PDF]
Seminars in Immunopathology, 2021 For a long time, host cell death during parasitic infection has been considered a reflection of tissue damage, and often associated with disease pathogenesis. However, during their evolution, protozoan and helminth parasites have developed strategies to interfere with cell death so as to spread and survive in the infected host, thereby ascribing a more
Herkel, Johannes, Schmidt-Arras, Dirk
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