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Lipid Mediators in Inflammation [PDF]

open access: yesMicrobiology Spectrum, 2016
Lipids are potent signaling molecules that regulate a multitude of cellular responses, including cell growth and death and inflammation/infection, via receptor-mediated pathways. Derived from polyunsaturated fatty acids (PUFAs), such as arachidonic acid (
Bennett, M, Gilroy, DW
core   +5 more sources

Serum T2-High Inflammation Mediators in Eosinophilic COPD [PDF]

open access: yesBiomolecules
Eosinophils are central inflammatory cells in asthma; however, a portion of patients with chronic obstructive pulmonary disease (COPD) have blood or sputum eosinophilia, a condition termed eosinophilic COPD (eCOPD), which may contribute to the ...
Andrius Januskevicius   +5 more
doaj   +2 more sources

Mediators of Inflammation in Pulmonary Diseases [PDF]

open access: yesMediators of Inflammation, 2015
Inflammation is supposed to play a great role in the pathogenesis of the most common diseases of the respiratory system. In Chronic Obstructive Pulmonary Disease (COPD), which is a major cause of morbidity and mortality all around the world, smoking mainly causes the initiation of the inflammatory process that leads to an impaired respiratory function.
Kostas Spiropoulos   +4 more
doaj   +4 more sources

Combined In Silico, In Vivo, and In Vitro Studies Shed Insights into the Acute Inflammatory Response in Middle-Aged Mice [PDF]

open access: yes, 2013
We combined in silico, in vivo, and in vitro studies to gain insights into age-dependent changes in acute inflammation in response to bacterial endotoxin (LPS). Time-course cytokine, chemokine, and NO2-/NO3- data from "middle-aged" (6-8 months old) C57BL/
A Torres   +63 more
core   +16 more sources

Mediators of inflammation [PDF]

open access: yesCurrent Opinion in Immunology, 1997
Therapeutic studies and genetically engineered animals have elucidated the inflammatory roles of cytokines and chemokines in autoimmune disease. Most unexpected has been a continuum of recent evidence demonstrating that inflammatory mediators are crucial in lymphoid organ development, thus suggesting that these hitherto unrelated processes have common ...
R, Sacca, C A, Cuff, N H, Ruddle
openaire   +3 more sources

The light and shadow of senescence and inflammation in cardiovascular pathology and regenerative medicine [PDF]

open access: yes, 2017
Recent epidemiologic studies evidence a dramatic increase of cardiovascular diseases, especially associated with the aging of the world population. During aging, the progressive impairment of the cardiovascular functions results from the compromised ...
Cavarretta, Elena   +9 more
core   +16 more sources

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