Results 1 to 10 of about 569,903 (346)

Lipid Mediators in Inflammation [PDF]

Microbiology Spectrum, 2016
ABSTRACTLipids are potent signaling molecules that regulate a multitude of cellular responses, including cell growth and death and inflammation/infection, via receptor-mediated pathways. Derived from polyunsaturated fatty acids (PUFAs), such as arachidonic acid (AA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA), each lipid displays ...
Bennett, M, Gilroy, DW
openaire   +7 more sources

Sequential release of cytokines, lipid mediators and nitric oxide in experimental colitis [PDF]

Mediators of Inflammation, 1995
The object of this study was to establish whether different pro- and anti-inflammatory mediators were formed in colonic tissue from experimental colitis depending on the course of the disease.
A. P. M. van Dijk, Z. J. Keuskamp, J. H. P. Wilson, F. J. Zijlstra   +3 more
doaj   +4 more sources

Quantifying the relevance of different mediators in the human immune cell network [PDF]

Bioinformatics. 2005 Apr 15;21(8):1639-43. Epub 2004 Dec 21., 2004
Immune cells coordinate their efforts for the correct and efficient functioning of the immune system (IS). Each cell type plays a distinct role and communicates with other cell types through mediators such as cytokines, chemokines and hormones, among others, that are crucial for the functioning of the IS and its fine tuning.
Castellani, Gastone C., Franceschi, Claudio, Latora, Vito, Marchiori, Massimo, Remondini, Daniel, Tieri, Paolo, Valensin, Silvana   +6 more
arxiv   +3 more sources

The Role of Inflammatory Mediators in the Pathogenesis of Alzheimer’s Disease [PDF]

Sultan Qaboos University Medical Journal, 2015
Alzheimer’s disease (AD), a neurodegenerative disorder associated with advanced age, is the most common cause of dementia globally. AD is characterised by cognitive dysfunction, deposition of amyloid plaques, neurofibrillary tangles and neuro ...
Gholamreza Azizi, Shadi S. Navabi, Ahmed Al-Shukaili, Mir H. Seyedzadeh, Reza Yazdani, Abbas Mirshafiey   +5 more
doaj   +6 more sources

Mediators of Inflammation in Pulmonary Diseases [PDF]

Mediators of Inflammation, 2015
Inflammation is supposed to play a great role in the pathogenesis of the most common diseases of the respiratory system. In Chronic Obstructive Pulmonary Disease (COPD), which is a major cause of morbidity and mortality all around the world, smoking mainly causes the initiation of the inflammatory process that leads to an impaired respiratory function.
Kostas Spiropoulos, Nikolaos Siafakas, Marc Miravitlles, Francesco Blasi, Kiriakos Karkoulias   +4 more
doaj   +5 more sources

Distinct etiology of chronic inflammation – implications on degenerative diseases and cancer therapy [PDF]

Frontiers in Immunology
Acute inflammation is elicited by lipid and protein mediators in defense of the host following sterile or pathogen-driven injury. A common refrain is that chronic inflammation is a result of incomplete resolution of acute inflammation and behind the ...
Krishna Rao Maddipati
doaj   +2 more sources

Serum T2-High Inflammation Mediators in Eosinophilic COPD [PDF]

Biomolecules
Eosinophils are central inflammatory cells in asthma; however, a portion of patients with chronic obstructive pulmonary disease (COPD) have blood or sputum eosinophilia, a condition termed eosinophilic COPD (eCOPD), which may contribute to the ...
Andrius Januskevicius, Egle Vasyle, Airidas Rimkunas, Jolita Palacionyte, Virginija Kalinauskaite-Zukauske, Kestutis Malakauskas   +5 more
doaj   +2 more sources

Vision for Mediators of Inflammation [PDF]

Mediators of Inflammation, 2020
Anshu Agrawal
doaj   +3 more sources

Mediators of inflammation [PDF]

Current Opinion in Immunology, 1997
Therapeutic studies and genetically engineered animals have elucidated the inflammatory roles of cytokines and chemokines in autoimmune disease. Most unexpected has been a continuum of recent evidence demonstrating that inflammatory mediators are crucial in lymphoid organ development, thus suggesting that these hitherto unrelated processes have common ...
Carolyn A. Cuff, Nancy H. Ruddle, Rosalba Sacca   +2 more
openaire   +4 more sources

Combined In Silico, In Vivo, and In Vitro Studies Shed Insights into the Acute Inflammatory Response in Middle-Aged Mice [PDF]

, 2013
We combined in silico, in vivo, and in vitro studies to gain insights into age-dependent changes in acute inflammation in response to bacterial endotoxin (LPS). Time-course cytokine, chemokine, and NO2-/NO3- data from "middle-aged" (6-8 months old) C57BL/
A Torres, AA Beharka, AK Schroder, C Franceschi, C Franceschi, C Nathan, CC Chow, CE Lagoa, CR Gomez, DC Morrison, DE Zak, Derek Barclay, Derya Unutmaz, DO Adams, E Alvarez, E Cevenini, EZ Bagci, EZ Bagci, F Aujard, F L’Episcopo, FM Ocasio, G Nieman, H Ochi, H Saito, H Wang, IR Turnbull, J Plowden, JM Cavaillon, JM Prince, John Bartels, K Tateda, KM Greeneltch, L Alvarez-Rodriguez, L Ferrucci, M Gurven, MA West, MJ Yang, R Kumar, R Ostan, RA Kohman, Rami A. Namas, RB Effros, RJ Fahy, RL Zhang, Rosemary Hoffman, Ruben Zamora, S Daun, S Gordon, SC Kang, SF Bradley, SN Zykova, T Inamizu, Timothy R. Billiar, TP Plackett, U Fagiolo, W Schumer, W Wiktor-Jedrzejczak, Y Hasegawa, Y Ito, Y Vodovotz, Y Vodovotz, Y Vodovotz, Yoram Vodovotz, Z Yang   +63 more
core   +16 more sources