Results 141 to 150 of about 569,903 (346)

CXC chemokines generate age-related increases in neutrophil-mediated brain inflammation and blood–brain barrier breakdown [PDF]

, 1998
Daniel C. Anthony, Robert Dempster, Sara Fearn, John M. Clements, Graham Wells, V. Hugh Perry, Katharine Walker   +6 more
openalex   +1 more source

Plasma‐activated media selectively induces apoptotic death via an orchestrated oxidative stress pathway in high‐grade serous ovarian cancer cells

Molecular Oncology, EarlyView.
High‐grade serous ovarian cancer (HGSOC) is the most common and aggressive type of ovarian cancer with urgent need for new treatment strategies. This study evaluates plasma‐activated media (PAM) as a novel treatment for HGSOC, showing its ability to selectively induce oxidative stress and apoptosis in HGSOC cell lines, patient ascites cells and primary
Lorena T. Davies, Raja Ganesen, John Toubia, Sung‐Ha Hong, Sushil Kumar KC, Martin K. Oehler, Carmela Ricciardelli, Endre J. Szili, Nirmal Robinson, Melissa R. Pitman   +9 more
wiley   +1 more source

Characteristics of inflammatory mediators in dental pulp inflammation and the potential for their control

Frontiers in Dental Medicine
Dental pulp is a mesenchymal connective tissue located inside the rigid encasement of the dentin. When bacteria or bacterial products invade the dental pulp, inflammation known as pulpitis is induced in this tissue.
Nobuyuki Kawashima, Takashi Okiji
doaj   +1 more source

The role of polymorphonuclear leukocytes and oxygen‐derived free radicals in experimental acute pancreatitis: mediators of local destruction and activators of inflammation [PDF]

, 1999
Bertram Poch, Frank Gansauge, Bettina Rau, Uwe A. Wittel, Susanne Gansauge, Andreas K. Nüssler, Michael Schoenberg, H. G. Beger   +7 more
openalex   +1 more source

Unraveling epigenetic heterogeneity across gastrointestinal adenocarcinomas through a standardized analytical framework

Molecular Oncology, EarlyView.
This study shows that patients with gastrointestinal adenocarcinomas can be stratified into six distinct subtypes based on genome‐scale DNA methylation profiling. This stratification, achieved using a robust analytical framework, aligns with established tumor characteristics and holds potential to support prognostication.
Rita Pinto, Hege Marie Vedeld, Guro Elisabeth Lind, Marine Jeanmougin   +3 more
wiley   +1 more source

Retracted: The Anti-Inflammatory Effects of Shinbaro3 Is Mediated by Downregulation of the TLR4 Signalling Pathway in LPS-Stimulated RAW 264.7 Macrophages

Mediators of Inflammation, 2020
Mediators of Inflammation
doaj   +1 more source

Helicobacter pylori-Induced Mucosal Inflammation Is Th1 Mediated and Exacerbated in IL-4, But Not IFN-γ, Gene-Deficient Mice [PDF]

, 2000
Lesley E. Smythies, Ken B. Waites, J. Russell Lindsey, Paul Harris, P Ghiara, Phillip D. Smith   +5 more
openalex   +1 more source

The PTTG1/VASP axis promotes oral squamous cell carcinoma metastasis by modulating focal adhesion and actin filaments

Molecular Oncology, EarlyView.
VASP was found to be overexpressed in metastatic oral squamous cell carcinoma (OSCC) tissues. Notably, PTTG1‐ and VASP‐deficient OSCC cells demonstrated suppressed metastatic properties by disrupting the interaction between the cytoskeleton and focal adhesion (FAs) in the filopodia region.
Suyeon Park, Sang Shin Lee, Shihyun Kim, Yeonjun Lee, Gyeonwon Park, Jung Oh Kim, Jongho Choi   +6 more
wiley   +1 more source

Protease-Activated Receptor 1 Mediates Thrombin-Dependent, Cell-Mediated Renal Inflammation in Crescentic Glomerulonephritis [PDF]

, 2000
Malcolm A. Cunningham, Éric Rondeau, Xin Chen, Shaun R. Coughlin, Stephen R. Holdsworth, Peter G. Tipping   +5 more
openalex   +1 more source

Lysosomal cysteine proteinases as mediators of inflammation and tumor spread [PDF]

, 1992
Assfalg-Machleidt, Irmgard, Jochum, Marianne, Jänicke, F., Machleidt, W., Schmitt, M.   +4 more
core   +1 more source