Results 141 to 150 of about 4,346,916 (366)

TO027BETA-HYDROXYBUTYRATE INHIBITS NLRP3-MEDIATED INFLAMMATION AND DELAYS PROGRESSIVE RENAL FAILURE DURING PRIMARY HYPEROXALURIA RELATED KIDNEY STONE DISEASE [PDF]

open access: bronze, 2016
Shrikant R. Mulay   +6 more
openalex   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Supplementary Figure 3 from Epigenetic Suppression of SERPINB1 Promotes Inflammation-Mediated Prostate Cancer Progression

open access: gold, 2023
Irina Lerman   +9 more
openalex   +1 more source

Inflammasome activation and pyroptosis mediate coagulopathy and inflammation in Salmonella systemic infection [PDF]

open access: green, 2023
Ankit Pandeya   +8 more
openalex   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Streptococcus thermophilus Attenuates Inflammation in Septic Mice Mediated by Gut Microbiota

open access: gold, 2020
Fu Han   +10 more
openalex   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

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