Results 171 to 180 of about 4,346,916 (366)

Circulating Platelets as Mediators of Immunity, Inflammation, and Thrombosis

Circulation Research, 2018
Milka Koupenova, L. Clancy, Heather A. Corkrey, J. Freedman   +3 more
semanticscholar   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Retracted: Treadmill Training Increases SIRT-1 and PGC-1α Protein Levels and AMPK Phosphorylation in Quadriceps of Middle-Aged Rats in an Intensity-Dependent Manner

Mediators of Inflammation, 2017
Mediators of Inflammation
doaj   +1 more source

Responsive Theranostic Nanoprobe for Ratiometric Photoacoustic Monitoring of Hypochlorous Acid‐Mediated Inflammation in Cancer Photothermal Therapy [PDF]

Huayue Zhang, Miaomiao Wu, Firasti Agung Nugrahening Sumadi, Changkui Fu, Qingtao Meng, Mazen Alanazi, Zexi Zhang, Zhi Ping Xu, Hang T. Ta, Run Zhang   +9 more
openalex   +1 more source

C-Jun/C7ORF41/NF-κB axis mediates hepatic inflammation and lipid accumulation in NAFLD

, 2020
Fengjuan Yan, Xu Wang, Song-En Wang, Hai-Ting Hong, Jun Lü, Qin Ye, Yuan‐Lin Zheng, Yong‐Jian Wang   +7 more
openalex   +1 more source

Sphingosine‐1‐phosphate receptor 1 mediates elevated IL‐6 signaling to promote chronic inflammation and multitissue damage in sickle cell disease [PDF]

, 2018
Shushan Zhao, Morayo G. Adebiyi, Yujin Zhang, Jacob Couturier, Xuegong Fan, Hongqi Zhang, Rodney E. Kellems, Dorothy E. Lewis, Yang Xia   +8 more
openalex   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Retracted: Further Increase in the Expression of Activation Markers on Monocyte-Derived Dendritic Cells in Coronary Artery Disease Patients with Ectasia Compared to Patients with Coronary Artery Disease Alone

Mediators of Inflammation, 2020
Mediators of Inflammation
doaj   +1 more source

Treating inflammation and infection in the 21st century: new hints from decoding resolution mediators and mechanisms

The FASEB Journal, 2017
C. Serhan
semanticscholar   +1 more source