Results 181 to 190 of about 3,890,295 (331)

Inflammatory Mediators of Cerebral Endothelium: A Role in Ischemic Brain Inflammation

, 2000
Danica Stanimirovic, Kei Satoh
openalex   +2 more sources

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Circulating interleukin‐6 mediates the febrile response to localised inflammation in rats

, 2000
T. Cartmell, Stephen Poole, Andrew V. Turnbull, N. J. Rothwell, Giamal N. Luheshi   +4 more
openalex   +1 more source

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

Molecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach, Nilesh Chatterjee, Kellie Spahr, Gilberto Serrano de Almeida, Anabel Varela‐Carver, Taimur T. Shah, Mathias Winkler, Hashim U. Ahmed, Charlotte L. Bevan   +8 more
wiley   +1 more source

RETRACTION: Inhibitory Effect of Matrine on Blood-Brain Barrier Disruption for the Treatment of Experimental Autoimmune Encephalomyelitis

Mediators of Inflammation
Mediators of Inflammation
doaj   +1 more source

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

Molecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche, Renske Imschoot, Béatrice Lintermans, Lode Denolf, Joachim Taminau, Charlotte Fieuws, Geert Berx, Kris Gevaert, Kathleen B. M. Claes   +8 more
wiley   +1 more source

Inflammatory Mediators in Uveitis: Differential Induction of Cytokines and Chemokines in Th1- Versus Th2-Mediated Ocular Inflammation [PDF]

, 2002
Ellen F. Foxman, Meifen Zhang, Stephen D. Hurst, Tony Muchamuel, Defen Shen, Eric F. Wawrousek, Chi‐Chao Chan, Igal Gery   +7 more
openalex   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

Molecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner, Markus Eckstein, Christoph Mark, Matthias W. Beckmann, Arndt Hartmann, Pamela L. Strissel, Reiner Strick   +6 more
wiley   +1 more source

Synergistic effect of IL-12 and IL-18 in driving intestinal Th1-mediated inflammation in Crohn's disease

, 2000
Akira Okazawa, Takanori Kanai∥, Mamoru Watanabe, Toshiro Sate, Nagamu Inoue, Hiromasa Ishii, Masao Ikeda, Masashi Kurimoto, Toshifumi Hibi∥   +8 more
openalex   +1 more source

Evidence for a perforin‐mediated mechanism controlling cardiac inflammation in Trypanosoma cruzi infection [PDF]

, 2002
Andrea Henriques‐Pons, Gabriel Melo de Oliveira, Maurício M. Paiva, ALEXANDRE F. S. CORREA, Marcos Meuser Batista, Rodrigo da Cunha Bisaggio, Chau‐Ching Liu, Vinı́cius Cotta-de-Almeida, Cláudia Mara Lara Melo Coutinho, Pedro M. Persechini, Tania C. de Araújo-Jorge   +10 more
openalex   +1 more source