Results 11 to 20 of about 362,551 (290)

Basal and PGF2α-stimulated secretion of pro-inflammatory cytokines from 3T3-L1 adipocyte-like cells [PDF]

open access: yesBioDiscovery, 2017
Adipocytes were recently identified as an important source of endocrine and paracrine mediators, regulating the metabolism and activity of various cell types and body functions. 3T3-L1 preadipocytes are useful model for physiological, pharmacological and
Bilyana Ilieva   +3 more
doaj   +3 more sources

Specialized Pro-Resolving Mediators in Neuroinflammation: Overview of Studies and Perspectives of Clinical Applications

open access: yesMolecules, 2022
Specialized pro-resolving mediators (SPMs) are lipid mediators derived from poly-unsaturated fatty acids (PUFAs) which have been demonstrated to have an important role in the inflammation environment, preventing an overreaction of the organism and ...
Mariarosaria Valente   +4 more
doaj   +1 more source

Role of Extracellular Vesicles in Cell Death and Inflammation

open access: yesCells, 2021
Extracellular vesicles (EVs) have been identified as novel mediators of intercellular communication. They work via delivering the sequestered cargo to cells in the close vicinity, as well as distant sites in the body, regulating pathophysiological ...
Rahul Sanwlani, Lahiru Gangoda
doaj   +1 more source

Cytokine status’ pattern in acute period of ischemic stroke subtypes

open access: yesZaporožskij Medicinskij Žurnal, 2017
Purpose The aim of this study was to assess a different pattern of inflammatory mediators in relation of ischemic stroke subtypes in acute period. Materials and Methods. The study involved 482 patients with different ischemic stroke (IS) subtypes.
S. I. Shkrobot   +3 more
doaj   +1 more source

Mast cells as the strength of the inflammatory process

open access: yesPolish Journal of Pathology, 2017
The inflammatory process is a complex host defence mechanism aimed at the elimination of deleterious factors disturbing homeostasis. Inflammation consists of several interdependent stages controlled by a wide range of mediators. Those include acute phase
Joanna Pastwińska   +3 more
doaj   +1 more source

Geographic variation in walking activity in the red flour beetle Tribolium castaneum

open access: yesPopulation Ecology, EarlyView.
This study examined whether there is geographic variation in field populations, focusing on the moving activity in the red flour beetle Tribolium castaneum. Results showed significant differences in moving activity among field populations but no correlation with latitude or meteorological factors.
Kentarou Matsumura
wiley   +1 more source

Infection Models for Pine Wilt Disease on the Basis of Vector Behaviors

open access: yesPopulation Ecology, EarlyView.
Infection models for pine wilt disease without vector density were built to estimate the transmission coefficient of the pathogenic nematode. The models successfully simulated the annual change in the density of infected trees for four pine stands. ABSTRACT Pine wilt disease is caused by the pinewood nematode (Bursaphelenchus xylophilus Steiner et ...
Katsumi Togashi
wiley   +1 more source

Non-inflammatory Physiology of “Inflammatory” Mediators – Unalamation, a New Paradigm

open access: yesFrontiers in Immunology, 2020
Many small molecules (mostly lipids derived from polyunsaturated fatty acids) and proteins (e. g., cytokines and chemokines) are labeled as inflammatory mediators for their role in eliciting physiological responses to injury.
Krishna Rao Maddipati
doaj   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Resolution of Inflammation in Neurodegenerative Diseases: The Role of Resolvins

open access: yesMediators of Inflammation, 2020
Acute inflammation has been described as a reactive dynamic process, promoted by the secretion of proinflammatory mediators, including lipid molecules like leukotrienes and prostaglandins, and counterbalanced by proresolving mediators including omega-3 ...
Sajad Chamani   +6 more
doaj   +1 more source

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