Results 11 to 20 of about 569,903 (346)
Efferocytes release extracellular vesicles to resolve inflammation and tissue injury via prosaposin-GPR37 signaling. [PDF]
Macrophages release soluble mediators following efferocytic clearance of apoptotic cells to facilitate intercellular communication and promote the resolution of inflammation. However, whether inflammation resolution is modulated by extracellular vesicles
Austin-Williams, S+8 more
core +1 more source
Pro-Resolving Lipid Mediators (SPMs) and Their Actions in Regulating miRNA in Novel Resolution Circuits in Inflammation [PDF]
Unresolved inflammation is associated with several widely occurring diseases such as arthritis, periodontal diseases, cancer, and atherosclerosis.
Recchiuti, Antonio+1 more
core +13 more sources
Mediators of liver inflammation and carcinogenesis [PDF]
For a long time, host cell death during parasitic infection has been considered a reflection of tissue damage, and often associated with disease pathogenesis. However, during their evolution, protozoan and helminth parasites have developed strategies to interfere with cell death so as to spread and survive in the infected host, thereby ascribing a more
Herkel, Johannes, Schmidt-Arras, Dirk
openaire +4 more sources
IL-21 receptor expression in human tendinopathy [PDF]
The pathogenetic mechanisms underlying tendinopathy remain unclear, with much debate as to whether inflammation or degradation has the prominent role.
Campbell, Abigail L.+8 more
core +19 more sources
A dental prosthesis will only be successful if the restoration lasts for a long period and does not cause any illness. The presence of permanent prosthetic restorations has been linked to an increased risk of periodontal infections, according to a large ...
Lucian Paul Dragomir+7 more
doaj +1 more source
Path-specific causal decomposition analysis with multiple correlated mediator variables [PDF]
A causal decomposition analysis allows researchers to determine whether the difference in a health outcome between two groups can be attributed to a difference in each group's distribution of one or more modifiable mediator variables. With this knowledge, researchers and policymakers can focus on designing interventions that target these mediator ...
arxiv +1 more source
Basal and PGF2α-stimulated secretion of pro-inflammatory cytokines from 3T3-L1 adipocyte-like cells [PDF]
Adipocytes were recently identified as an important source of endocrine and paracrine mediators, regulating the metabolism and activity of various cell types and body functions. 3T3-L1 preadipocytes are useful model for physiological, pharmacological and
Bilyana Ilieva+3 more
doaj +3 more sources
INFLAMMATION AS A FUNDAMENTAL PATHOLOGICAL PROCESS: LECTURE 1 (ALTERATION, VASCULAR REACTIONS)
Inflammation is the most widespread pathological process in medical practice. Inflammation is the basis of the vast majority of diseases. In this connection, the topic is actual for any medical student, as well as a doctor of any specialty.
Svetlana N. Serebrennikova+3 more
doaj +1 more source
Prosaposin mediates inflammation in atherosclerosis
Prosaposin mediates inflammation in experimental and human atherosclerosis and is associated with cellular metabolism and mTOR signaling.
Yu-Xiang Ye+42 more
openaire +5 more sources
Specialized pro-resolving mediators (SPMs) are lipid mediators derived from poly-unsaturated fatty acids (PUFAs) which have been demonstrated to have an important role in the inflammation environment, preventing an overreaction of the organism and ...
Mariarosaria Valente+4 more
doaj +1 more source