Results 221 to 230 of about 3,890,295 (331)

Matrigel inhibits elongation and drives endoderm differentiation in aggregates of mouse embryonic stem cells

FEBS Open Bio, EarlyView.
Stem cell‐based embryo models (SCBEMs) are valuable to study early developmental milestones. Matrigel, a basement membrane matrix, is a critical substrate used in various SCBEM protocols, but its role in driving stem cell lineage commitment is not clearly defined.
Atoosa Amel, Rachel Brown, Alexa Rabeling, Mubeen Goolam   +3 more
wiley   +1 more source

Unraveling Osteoarthritis: Mechanistic Insights and Emerging Therapies Targeting Pain and Inflammation. [PDF]

Biomolecules
Alad M, Yousef F, Epure LM, Lui A, Grant MP, Merle G, Eliopoulos N, Barralet J, Antoniou J, Mwale F.   +9 more
europepmc   +1 more source

Mechanism by Which Il-16 Generated by Mast Cells Mediates Allergic Inflammation

, 2001
Pio Conti, Duraisamy Kempuraj, William Boucher, Richard Létourneau, Theoharis C. Theoharides   +4 more
openalex   +1 more source

Neurotoxic amyloid β‐peptide and tau produce cytokine‐like effects on PMCA in glioblastoma cell lines, enhancing its activity and isoforms expression

FEBS Open Bio, EarlyView.
Two biomarkers of Alzheimer's disease, amyloid β‐peptide (Aβ) and tau, induce the transformation of U‐251 and other glioblastoma cell lines into neurotoxic A1‐like reactive astrocytes. This transformation is produced by cytokines and is followed by upregulation of PMCA activity and isoform expression, and is closely associated with inflammation, as ...
María Berrocal, Alberto Alvarez‐Barrientos, Ana M. Mata   +2 more
wiley   +1 more source

The Junction of Allergic Inflammation and Atherosclerosis: Pathways and Clinical Implications-A Review. [PDF]

Life (Basel)
Valcovici M, Iacob MS, Sharma A, Pah AM, Marin-Bancila L, Berceanu MMV, Velimirovici MD, Dinu AR, Drăgan SR, Kundnani NR.   +9 more
europepmc   +1 more source

OP0033 Systemic adenovirus mediated gene therapy using a chimeric soluble il-1 receptor type ii ?igg protein reduces acute inflammation in antigen-induced arthritis

, 2001
Jean Dudler, Roberto Salvi, Nathalie Busso, Véronique Chobaz-Péclat, A. So   +4 more
openalex   +1 more source

Iron‐dependent lysosomal LDL oxidation induces the expression of scavenger receptor A in human THP‐1 monocytes

FEBS Open Bio, EarlyView.
In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna, Richard Buchal, Martin Leníček, Amit Shachak, Jan Pláteník   +4 more
wiley   +1 more source

Human epithelial cells trigger dendritic cell–mediated allergic inflammation by producing TSLP

, 2002
Vassili Soumelis, Pedro A. Reche, Holger Kanzler, Wei Yuan, G Kasili Edward, Bernhard Homey, Michel Gilliet, Steve Ho, S. V. Antonenko, Annti Lauerma, Kathleen M. Smith, Daniel M. Gorman, Sandra Zurawski, Jon Abrams, Satish Menon, Terri McClanahan, René de Waal Malefyt, Fernando Bazán, Robert A. Kastelein, Yong-Jun Liu   +19 more
openalex   +2 more sources

The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise

FEBS Open Bio, EarlyView.
Frailty syndrome exacerbates skeletal muscle degeneration via increased ECM deposition and myofiber loss. This study, using a murine model, demonstrates that endurance exercise attenuates these histopathological alterations, preserving muscle integrity. Findings support exercise as a viable strategy to counteract frailty‐induced musculoskeletal decline
Fujue Ji, Hae Sung Lee, Haesung Lee, Jong‐Hee Kim   +3 more
wiley   +1 more source

Specialized Pro-Resolving Lipid Mediators in Pulmonary Diseases: Molecular and Therapeutic Implications. [PDF]

Molecules
Ortega Á, Duran P, Garrido B, Manzano A, Navarro C, Silva A, Rojas M, De Sanctis JB, Radzioch D, Rivera-Porras D, Paredes CS, Bermúdez V.   +11 more
europepmc   +1 more source