Results 221 to 230 of about 635,488 (322)

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Sexually dimorphic developmental changes in rat spinal cord pain pathways following neonatal inflammation. [PDF]

Physiol Rep
Hedley KE, Cuskelly A, Quinn RK, Callister RJ, Hodgson DM, Tadros MA.   +5 more
europepmc   +1 more source

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

FEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner, César G. Prucca, Lucia Boffelli, Virginia A. Piqueras, Silvia G. Correa, Mariana Maccioni, Mario E. Guido   +6 more
wiley   +1 more source

Mediators of Gut Mucosal Immunity and Inflammation

Mediators of Inflammation, 2015
Ishak Ozel Tekin, H. Barbaros Oral, Ronit Shiri-Sverdlov   +2 more
doaj   +1 more source

Hyperglycemia Induced in Sprague-Dawley Rats Modulates the Expression of CD36 and CD69 During Wound Healing. [PDF]

Int J Mol Sci
Ho V, Tran T, Patel J, Teshome B, Rai V.
europepmc   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Mediators of Interorgan Crosstalk in Metabolic Inflammation

Mediators of Inflammation, 2013
Massimo Collino, Assaf Rudich, Daniel Konrad   +2 more
doaj   +1 more source

Role of ADAR2-mediated innate immune responses in vascular inflammation and atherosclerosis [PDF]

Michael Amponsah-Offeh, Giorgia Ciliberti, Maria Polycarpou‐Schwarz, Kimon Stamatelopoulos, Markus Sperandio, Andrey Turchinovich, Simon Tual‐Chalot, Konstantinos Stellos   +7 more
openalex   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

Resolvin E1 as a Potential Biomarker of Tendon Retraction Severity in Rotator Cuff Tears. [PDF]

J Clin Med
Taskin R, Gülten S, Bildirici MA, Kesbiç OS.   +3 more
europepmc   +1 more source