Results 251 to 260 of about 4,346,916 (366)

Interplay between RNA‐protein interactions and RNA structures in gene regulation

FEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko, Mauro Scaravilli, Minna‐Liisa Änkö   +2 more
wiley   +1 more source

Mediators of Gut Mucosal Immunity and Inflammation

Mediators of Inflammation, 2015
Ishak Ozel Tekin, H. Barbaros Oral, Ronit Shiri-Sverdlov   +2 more
doaj   +1 more source

Response of alveolar macrophages to inhaled particulates [PDF]

, 2002
Dörger, Martina, Krombach, Fritz
core   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Mediators of Interorgan Crosstalk in Metabolic Inflammation

Mediators of Inflammation, 2013
Massimo Collino, Assaf Rudich, Daniel Konrad   +2 more
doaj   +1 more source

Inflammation impairs post-hospital discharge growth among children hospitalised with acute illness in sub-Saharan Africa and south Asia. [PDF]

Nat Commun
Njunge JM, Mudibo EO, Bogaert J, Orindi B, Sande CJ, Bourdon C, Tigoi C, Ngari MM, Ngao N, Omer E, Gumbi W, Musyimi R, Timbwa M, Mwaringa S, Gwela A, Thitiri J, Mupere E, Lancioni CL, Gonzales GB, Singa BO, Mbale E, Voskuijl WP, Denno DM, Diallo AH, Bamouni RM, Chisti MJ, Shahid ASMSB, Ahmed T, Saleem AF, Ali SA, Uhlig HH, Tickell KD, Bandsma RHJ, Walson JL, Berkley JA.   +34 more
europepmc   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source

Pro-resolving lipid mediators are leads for resolution physiology

Nature, 2014
C. Serhan
semanticscholar   +1 more source

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

FEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

Maresins. [PDF]

Biomolecules
Berrocal-Navarrete F, Marín-Sanhueza P, Norambuena-González R, Quiñones San Martín M, Herrera-Vielma F, González DR, Zúñiga-Hernández J.   +6 more
europepmc   +1 more source