Results 261 to 270 of about 4,677,756 (310)
Some of the next articles are maybe not open access.
The inflammatory milieu in idiopathic inflammatory myositis
Current Rheumatology Reports, 2009The idiopathic inflammatory myopathies (IIM) are systemic autoimmune diseases that have predominant mononuclear inflammatory cell infiltrates in the skeletal muscle. The cells that are typically involved in the pathogenesis of disease are B-lymphocytes, T-lymphocytes, macrophages, dendritic cells, and natural killer cells. However, in addition to these
Ann M, Reed, Floranne, Ernste
openaire +2 more sources
Best Practice & Research Clinical Rheumatology, 1995
New information regarding myositis specific autoantibodies, histopathologic analysis of muscle biopsy specimens, and immunogenetic features of the different serologic subsets of disease has greatly increased our understanding of the pathogenesis of the inflammatory myopathies.
C V, Oddis, T A, Medsger
openaire +2 more sources
New information regarding myositis specific autoantibodies, histopathologic analysis of muscle biopsy specimens, and immunogenetic features of the different serologic subsets of disease has greatly increased our understanding of the pathogenesis of the inflammatory myopathies.
C V, Oddis, T A, Medsger
openaire +2 more sources
British Journal of Hospital Medicine, 2009
Before considering markers, it is first appropriate to consider inflammation (Latin, inflamatio, to set on fire). Inflammation is a complex response by an organism to injury, either resulting from invasion by pathogenic organisms, traumatic cell damage or irritants.
openaire +2 more sources
Before considering markers, it is first appropriate to consider inflammation (Latin, inflamatio, to set on fire). Inflammation is a complex response by an organism to injury, either resulting from invasion by pathogenic organisms, traumatic cell damage or irritants.
openaire +2 more sources
Clinical Immunology and Immunopathology, 1992
The immune system produces cytokines and other humoral factors to protect the host when threatened by inflammatory agents, microbial invasion, or injury. In some cases this complex defense network successfully restores normal homeostasis, but at other times the overproduction of immunoregulatory mediators may actually prove deleterious to the host ...
openaire +2 more sources
The immune system produces cytokines and other humoral factors to protect the host when threatened by inflammatory agents, microbial invasion, or injury. In some cases this complex defense network successfully restores normal homeostasis, but at other times the overproduction of immunoregulatory mediators may actually prove deleterious to the host ...
openaire +2 more sources
Continuum, 2022
This article outlines the salient clinical, serologic, electrophysiologic, imaging, and histopathologic findings and treatment options for the idiopathic inflammatory myopathies, including those related to immune checkpoint inhibitors and SARS-CoV-2.The classification of idiopathic inflammatory myopathies has improved with the integration of myositis ...
openaire +2 more sources
This article outlines the salient clinical, serologic, electrophysiologic, imaging, and histopathologic findings and treatment options for the idiopathic inflammatory myopathies, including those related to immune checkpoint inhibitors and SARS-CoV-2.The classification of idiopathic inflammatory myopathies has improved with the integration of myositis ...
openaire +2 more sources
Current Opinion in Neurology, 1996
As well as myositis caused by infectious agents, there is a spectrum of inflammatory myopathies representing diseases with autoimmune response. Subtypes differing in clinical features and morphological characteristics have been described. This review will emphasize new advances and recent efforts to identify pathogenetic mechanisms and immunological ...
D S, Tews, H H, Goebel
openaire +2 more sources
As well as myositis caused by infectious agents, there is a spectrum of inflammatory myopathies representing diseases with autoimmune response. Subtypes differing in clinical features and morphological characteristics have been described. This review will emphasize new advances and recent efforts to identify pathogenetic mechanisms and immunological ...
D S, Tews, H H, Goebel
openaire +2 more sources
Current Treatment Options in Neurology, 1999
Patients with polymyositis or dermatomyositis should be treated with prednisone (approximately 1 mg/kg/d) for an initial period of 4 to 6 weeks. Once improvement occurs, the dose should be tapered and converted to an alternate-day regimen, which should be continued for at least 12 months.
, Mastaglia, , Phillips, , Zilko
openaire +2 more sources
Patients with polymyositis or dermatomyositis should be treated with prednisone (approximately 1 mg/kg/d) for an initial period of 4 to 6 weeks. Once improvement occurs, the dose should be tapered and converted to an alternate-day regimen, which should be continued for at least 12 months.
, Mastaglia, , Phillips, , Zilko
openaire +2 more sources
Clinics in Dermatology, 2007
Skin ulcerations may develop as a manifestation of a variety of different diseases or may result from some nondisease phenomena. Inflammatory ulcers refer specifically to those ulcerations in which inflammation is the primary pathologic process resulting in lesion formation; that is, inflammation is the cause rather than the consequence of the ulcer ...
openaire +2 more sources
Skin ulcerations may develop as a manifestation of a variety of different diseases or may result from some nondisease phenomena. Inflammatory ulcers refer specifically to those ulcerations in which inflammation is the primary pathologic process resulting in lesion formation; that is, inflammation is the cause rather than the consequence of the ulcer ...
openaire +2 more sources
The Journal of Dermatologic Surgery and Oncology, 1993
A large number of diseases can eventuate in cutaneous ulceration. This article will review inflammatory disorders which by their nature can directly produce cutaneous breakdown and ulcer formation. Major emphasis is given to those disorders where recent knowledge has improved our understanding of the condition or where new therapeutic agents or ...
openaire +2 more sources
A large number of diseases can eventuate in cutaneous ulceration. This article will review inflammatory disorders which by their nature can directly produce cutaneous breakdown and ulcer formation. Major emphasis is given to those disorders where recent knowledge has improved our understanding of the condition or where new therapeutic agents or ...
openaire +2 more sources
2011
Diabetes mellitus and its complications have become one of the most important health problems in the world. Nowadays, diabetic nephropathy is the main cause of end-stage renal failure and need for renal substitutive therapy. The exact mechanisms leading to the development and progression of renal damage in diabetes are not yet completely known. Growing
Juan F, Navarro-González +1 more
openaire +2 more sources
Diabetes mellitus and its complications have become one of the most important health problems in the world. Nowadays, diabetic nephropathy is the main cause of end-stage renal failure and need for renal substitutive therapy. The exact mechanisms leading to the development and progression of renal damage in diabetes are not yet completely known. Growing
Juan F, Navarro-González +1 more
openaire +2 more sources