Results 271 to 280 of about 430,745 (290)

Trajectories of Adherence to Biologics in Patients With Inflammatory Bowel Diseases: A Large-Scale Multi-Regional Italian Study Through the VALORE Distributed Database. [PDF]

Pharmacoepidemiol Drug Saf
Giometto S, Spini A, Pellegrini G, Ingrasciotta Y, Bellitto C, Soardo F, L'Abbate L, Leoni O, Mazzone A, Ancona D, Stella P, Cavazzana A, Scapin A, Lopes S, Belleudi V, Ledda S, Carta P, Rossi P, Ejlli L, Sapigni E, Puccini A, Allotta A, Pollina SA, Da Cas R, Bucaneve G, Mangano AMP, Balducci F, Sorrentino C, Senesi I, Tuccori M, Gini R, Spila Alegiani S, Massari M, Trifirò G, Lucenteforte E.   +34 more
europepmc   +1 more source

Phospholipid Remodeling and Tri‐Layer Membrane Reconstruction Mediate Cognitive Effects of Humanized Milk Fat Globules in Neonatal Rats

Advanced Science, EarlyView.
Humanized milk fat globules (MFG) mimic the native composition and structure of human milk, achieved through remodeling of milk fat globule membrane phospholipid composition and reconstruction of the tri‐layer membrane structure. These humanized MFG exhibit improved structural stability and digestibility, and enhance neurodevelopment in formula‐fed rat
Shaolei Wang, Fengzhi Qiao, Jian He, Jianxin Fu, Tongjie Liu, Huaxi Yi, Qinghai Sheng, Lanwei Zhang, Kai Lin   +8 more
wiley   +1 more source

Comparative Safety of Janus Kinase Inhibitors vs Tumor Necrosis Factor Antagonists in Patients With Inflammatory Bowel Diseases. [PDF]

Clin Gastroenterol Hepatol
Ahuja D, Yeh KH, Patel SB, Lee HH, Goodwin SW, Solitano V, Ma C, Ananthakrishnan AN, Singh N, Jairath V, Xu R, Singh S.   +11 more
europepmc   +1 more source

7‐Ketodeoxycholic Acid Promotes Colonic Mucosal Healing by Inducing Calcium Release from Endoplasmic Reticulum via the TGR5‐IP3R Pathway

Advanced Science, EarlyView.
7‐KDCA functions by driving intestinal epithelial cell migration through induction of calcium release from the endoplasmic reticulum. The findings emphasize a previously unrecognized property of 7‐KDCA in regulating cell migration, a required process for effective epithelial restitution and repair that is particularly critical for patients with UC to ...
Jing Zhang, Feng Jiang, Wenxin Xia, Yilei Guo, Yanrong Zhu, Mianjiang Zhao, Lingzi Xiao, Zhifeng Wei, Yufeng Xia, Yue Dai   +9 more
wiley   +1 more source

Sexual Health in Women with Inflammatory Bowel Diseases: A Narrative Review. [PDF]

Healthcare (Basel)
Mercuri C, Bosco V, Juárez-Vela R, Guillari A, Simeone S, Doldo P.   +5 more
europepmc   +1 more source

Constructing Dual‐Atomic Fe─Fe Sites Nanozyme for Targeted Osteoarthritis Therapy through Mitigating Oxidative Stress and Cartilage Degeneration

Advanced Science, EarlyView.
A novel bimetallic nanozyme (Fe2–NCs) with well‐defined Fe–Fe active sites is synthesized through a host–guest coordination strategy, which exhibits an exceptional therapeutic efficacy in osteoarthritis therapy. Experimental and theoretical analyses uncover the intrinsic catalytic mechanism at the atomic level, offering fundamental insights and design ...
Ting Ying, Qi Wang, Dejian Li, Yao Wang, Pengfang Zhang, Chengqing Yi, Rui Zhu   +6 more
wiley   +1 more source

Novel Insights into the Pathogenesis of Inflammatory Bowel Diseases. [PDF]

Biomedicines
Calvez V, Puca P, Di Vincenzo F, Del Gaudio A, Bartocci B, Murgiano M, Iaccarino J, Parand E, Napolitano D, Pugliese D, Gasbarrini A, Scaldaferri F.   +11 more
europepmc   +1 more source

Oral Exposure to Food‐Grade Nanoparticles Poses a Risk of Alzheimer's Disease‐Like Symptoms by Triggering Autophagy Defects in Neurons

Advanced Science, EarlyView.
Three food‐grade nanomaterials induce dysregulated RyR‐Ca2+ signaling through epigenetic modifications. This dysregulation impairs the autophagic clearance process, ultimately leading to abnormal Aβ deposition and increase phosphorylated tau levels.
Jiaxin Shang, Jun Yan, He Lou, Xuanxi Jiang, Ziyue Wang, Yue Gao, Xiaohui Fan, Xiaoyan Lu   +7 more
wiley   +1 more source

Effects of inflammatory bowel diseases on sexual function in women. [PDF]

Ir J Med Sci
Aydamirov M, Erbayrak M, Karkin K, Vuruskan E, Tunckıran MA.   +4 more
europepmc   +1 more source