Results 231 to 240 of about 4,711,883 (288)

Once-Daily Postmastectomy Radiation Therapy Confers Excellent Locoregional Control for Inflammatory Breast Cancer. [PDF]

Int J Radiat Oncol Biol Phys
Pawloski KR, Xu A, Diskin B, Sevilimedu V, Bromberg J, Malhotra S, Khan AJ, Morrow M, Tadros AB.   +8 more
europepmc   +1 more source

Tracking CDK1 Dynamics With a Novel Biosensor Mouse and Clinical Cohorts to Predict CDK4/6 Inhibitor Sensitivity in ER+ Breast Cancer

Advanced Science, EarlyView.
Cyclin‐dependent kinase (CDK) 1 activity is a dynamic marker of treatment response in estrogen receptor positive breast cancer. Patient cohorts reveal CDK1 activity increases during progression to invasive disease, where high expression correlates with poor survival. Using a novel Cdk1 biosensor mouse alongside in vitro models, we demonstrate that CDK1
Sarah Alexandrou, Kristine J. Fernandez, Min Li Huang, Ewan K. A. Millar, Claire Vennin, Leila Eshraghi, Tan Dat Timothy Lam, Victoria Lee, Nyah C. Brooks, Janett Stoehr, Cristian Guaman Mendez, Douglas Strathdee, David Stevenson, David Herrmann, Sandra O'Toole, Paul Timpson, Max Nobis, C. Elizabeth Caldon   +17 more
wiley   +1 more source

Retrospective review of metastatic hormone receptor-positive inflammatory breast cancer patients reveals poor responses to cyclin dependent kinase 4/6 inhibition. [PDF]

Breast Cancer Res
Nasrazadani A, Tidwell RS, Kai M, Lim B, Valero V, Tripathy D, Saleem S, Debeb BG, Lucci A, Woodward WA, Layman RM, MDACC IBC Clinic and Research Team.   +11 more
europepmc   +1 more source

Immune Checkpoint Inhibitor as a Fifth Component of Lipid Nanoparticles Enables Lymph Node‐Targeting and Augments mRNA Vaccine Efficacy

Advanced Science, EarlyView.
Here, a PDL1 inhibitor is employed as a fifth component to modify lipid nanoparticles (LNPs). PDL1 inhibitor‐loaded LNPs show enhanced lymph node targeting, resulting in greater lymph node expansion, immune cell infiltration, and improved mRNA vaccine efficacy. This fifth component LNP could be a novel platform for mRNA vaccines.
Minki Ha, Jaehyun Kim, Seyoung Kim, Gonna Somu Naidu, Sungchan Cho, Seok‐Beom Yong   +5 more
wiley   +1 more source

Synthesis and Biological Evaluation of Herceptin-Conjugated Liposomes Loaded with Lipocalin-2 siRNA for the Treatment of Inflammatory Breast Cancer. [PDF]

Pharmaceuticals (Basel)
Flores-Colón M, Rivera-Serrano M, Peterson-Peguero EA, Vivas-Rivera PE, Valiyeva F, Vivas-Mejía PE.   +5 more
europepmc   +1 more source

How to Define Inflammatory Breast Cancer: A Systematic Review. [PDF]

Indian J Surg Oncol
Alipour S, Omranipour R, Zafarghandi M, Assarian A, Mir A.   +4 more
europepmc   +1 more source

Trends in Guideline-Concordant Care for Inflammatory Breast Cancer.

JAMA Netw Open
Tadros A, Diskin B, Sevilimedu V, Xu A, Vingan P, Nelson J, Iwai Y, Morrow M, Fayanju OM.   +8 more
europepmc   +1 more source

Single-cell and spatial transcriptome profiling identifies cellular heterogeneity and immunosuppressive tumor microenvironment in inflammatory breast cancer. [PDF]

J Adv Res
Sun X, Xia J, Jiang H, Duan T, Zhang C, Li Q, Yang Z, Zhang R, Ding X, Gu X, Xie X, Xie T, Sui X.   +12 more
europepmc   +1 more source

LMP7-Specific Inhibitor M3258 Modulates the Tumor Microenvironment of Triple-Negative Breast Cancer and Inflammatory Breast Cancer. [PDF]

Cancers (Basel)
Xie X, Lee J, Manyam GC, Pearson T, Walter-Bausch G, Friese-Hamim M, Zhao S, Jabs J, Manginelli AA, Piske N, Mrowiec T, Wolf CM, Kuntal BS, Tripathy D, Wang J, Sanderson MP, Ueno NT.   +16 more
europepmc   +1 more source

Use of natural language processing to identify patients with inflammatory breast cancer across a health-care system. [PDF]

JNCI Cancer Spectr
Kouzy R, Kai M, Le-Petross HT, Saleem S, MDACC Inflammatory Breast Cancer Team , Woodward WA.   +5 more
europepmc   +1 more source