Results 241 to 250 of about 1,012,717 (304)

High Humidity Exacerbates Psoriasiform Skin Disease Relapse by Increasing Tissue‐Resident Memory T Cells via Altering Skin Microbiota

Advanced Science, EarlyView.
We demonstrated that high humidity worsened psoriasis relapse in murine psoriasiform skin inflammation by increasing skin‐resident memory CD8+ cells via upregulating IL‐15Rα on keratinocytes. The increases in IL‐15Rα and memory CD8+ cells were attributed to S. nepalensis and its metabolite ADMA in skin exposed to high humidity.
Chun‐Ling Liang, Yuchao Chen, Chuanjian Lu, Huazhen Liu, Fenglian Qin, Sisi Dai, Feifei Qiu, Haiming Chen, Weihui Lu, Jonathan S. Bromberg, Zhenhua Dai   +10 more
wiley   +1 more source

Role of Inflammatory Cytokines and Endocrine Dysregulation in Pain-Related Cardiovascular and Metabolic Dysfunction: A Narrative Review. [PDF]

Cureus
Azeez OM, Olaniyi H, Oyovwi JO, Oyovwi MI, Okafor CP, Folasole A, Okeoma OI, Olaniyi AO.   +7 more
europepmc   +1 more source

Pre‐Encoded IFN‐I Sensitivity Exacerbates Memory T Cell Senescence in Solid Tumors

Advanced Science, EarlyView.
Type I interferon (IFN‐I) signaling promotes p21‐dependent cell cycle arrest in senescent tumor‐specific memory T cells, resulting in poor proliferative responses and solid tumor regression during cancer vaccination. Conversely, IFNα/β receptor blockade reinvigorates T cell proliferation to regress solid tumors and is more effective with increasing ...
Andrew Nguyen, Scott R Walsh, Li Deng, Lan Chen, Yonghong Wan   +4 more
wiley   +1 more source

Response to the Letter to the Editor, "Can case control study design investigate the association of BPG levels, inflammatory cytokines with valvular dysfunction". [PDF]

Indian Heart J
Kumar S.
europepmc   +1 more source

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang, Lihuan Shang, Xiaochun Chen, Xiangzhan Kong, Xiaojuan Wang, Linjia Jiang, Huiying Zhao, Yafeng Zhu, Cheng Huang, Shiyi Deng, Rui Zhang, Minghui Wang, Haoming Lin, Ping‐Pui Wong   +13 more
wiley   +1 more source

Evaluating the causal role of circulating inflammatory cytokines and plasma metabolites on aplastic anemia. [PDF]

Medicine (Baltimore)
Yang X, Lin R, Yang J, Zheng L.
europepmc   +1 more source

Baseline Inflammatory Cytokines Moderate Associations Between Intraoperative Oxidative Stress and Chronic Postsurgical Pain After Total Knee Arthroplasty: An Exploratory Study. [PDF]

J Pain Res
Durbhakula S, Rassu FS, Billings Th FT, Martin JR, Polkowski GG, Milne GL, Bruehl S.   +6 more
europepmc   +1 more source

Inflammatory Cytokines and Oxidative Stress Markers in Relation to Colorectal Cancer Risk: A Case-Cohort Study in a Korean Population. [PDF]

Cancers (Basel)
Park E, Baek S, Oh JK, Lim MK, Park EY.
europepmc   +1 more source

Pro-Inflammatory Cytokines as Core Mediators of Colonic Epithelial Barrier Dysfunction: Roles of TNF-α, IFN-γ, IL-1β, and IL-6. [PDF]

Int J Mol Sci
V Thanga Velu DP, Fauzi MB, Jaafar F, Mokhtar NM, Mokhtar MH, A Hamid A.   +5 more
europepmc   +1 more source

Near-Infrared Laser Photobiomodulation Reduces Pro-Inflammatory Cytokines in an In Vitro Model of Bronchopulmonary Dysplasia: A Preliminary Report. [PDF]

Med Sci (Basel)
Dani C, Fazi C, Cialdai F, Risaliti C, Notari L, Monici M.   +5 more
europepmc   +1 more source