Results 101 to 110 of about 1,622,130 (371)

Intravenous immunoglobulins as first-line treatment in idiopathic inflammatory myopathies: a pilot study

Rheumatology, 2020
Objectives We explored efficacy and safety of IVIg as first-line treatment in patients with an idiopathic inflammatory myopathy. Methods In this investigator-initiated phase 2 open-label study, we included 20 adults with a newly diagnosed, biopsy-proven ...
Johan Lim, F. Eftimov, C. Verhamme, E. Brusse, J. Hoogendijk, C. Saris, J. Raaphorst, R. D. de Haan, I. V. van Schaik, E. Aronica, M. de Visser, A. J. van der Kooi   +11 more
semanticscholar   +1 more source

Current pharmacological treatment of idiopathic inflammatory myopathies [PDF]

, 2016
The idiopathic inflammatory myopathies are uncommon and heterogeneous disorders. Their classification is based on distinct clinicopathologic features.
Alves, SC, Fasano, S, Isenberg, DA
core   +1 more source

Mitochondrial Transplantation as a Therapeutic Strategy for Inherited Mitochondrial Diseases

Advanced Science, EarlyView.
Mitochondrial transplantation (MTx) offers a promising therapeutic avenue for mitochondrial diseases. This review comprehensively evaluates MTx, differentiating its feasibility for mtDNA‐ and nDNA‐based disorders. It examines its potential for genetic correction, alongside inherent limitations, technical challenges, and crucial ethical considerations ...
Parmeshar Singh, Amir Tahavvori, Cyrus E. Kuschner, Blanca B. Espin, Jacob Kazmi, Sofhia V. Ramos, Tai Yin, Kei Hayashida, Kanako Ito‐Hagiwara, Yusuke Endo, Keitaro Yoshioka, Jun Hagiwara, Avijot Sohi, Alisha Oropallo, Ghania Haddad, Timmy Li, Lance B. Becker, Junhwan Kim   +17 more
wiley   +1 more source

Immune-Mediated Necrotizing Myopathy: An Often Misdiagnosed Entity

European Journal of Case Reports in Internal Medicine, 2015
Immune-mediated necrotizing myopathies (IMNM) are recognized as a subgroup of idiopathic inflammatory myopathies (IIM). IMNM are defined based on a combination of clinical presentation and laboratory studies, requiring a specific myopathological pattern ...
Joana Almeida Espírito Santo, Rui Garcia, Benilde Barbosa, Olinda Rebelo, José Pereira de Moura   +4 more
doaj   +1 more source

Electrophysiological, structural, and functional disorders in patients with inflammatory cardiomyopathy secondary to inflammatory myopathy

Annals of Noninvasive Electrocardiology, 2022
Background Inflammatory cardiomyopathy (IC) is a syndrome with chronic myocarditis and cardiac remodeling. This study aimed to explore predicting factors of adverse outcomes in patients with IC secondary to idiopathic inflammatory myopathy (IIM‐IC ...
Yingxian Liu, Jeffrey Hsu, Xiaohang Liu, Xue Lin, Yanlin Zhu, Fuwei Jia, Wei Wu, Wei Chen, Qian Wang, Ligang Fang   +9 more
doaj   +1 more source

Skeletal Muscle Biomarkers of Amyotrophic Lateral Sclerosis: A Large‐Scale, Multi‐Cohort Proteomic Study

Annals of Neurology, EarlyView.
Objective Biomarkers with clear contexts of use are important tools for amyotrophic lateral sclerosis (ALS) therapy development. Understanding their longitudinal trajectory in the untreated state is key to their use as potential markers of pharmacodynamic response.
Oleksandr Dergai, Joanne Wuu, Magdalena Koziczak‐Holbro, Andrea Malaspina, Volkan Granit, Jessica P. Hernandez, Anne Cooley, Ruchika Sachdev, Lili Yu, Michael Bidinosti, Ludivine Flotte, Mark Nash, Lori L. Jennings, James D. Berry, Lucie I. Bruijn, Sophie Brachat, Michael Benatar   +16 more
wiley   +1 more source

Atypical presentation of anti-small ubiquitin-like modifier 1 and melanoma differentiation-associated gene 5 antibody positive dermatomyositis presenting with significant inflammatory myopathy on biopsy and normal creatine kinase levels: A case report

SAGE Open Medical Case Reports
Idiopathic inflammatory myopathies are characterized by chronic inflammation of skeletal muscle. The main subtypes of idiopathic inflammatory myopathies include dermatomyositis, polymyositis, and necrotizing autoimmune myopathies.
Srikar Sama, Nidaa Rasheed, Kyle Shen, Negar Khanlou, Karam Han, Alicia Rodriguez-Pla   +5 more
doaj   +1 more source

Idiopathic inflammatory myopathies [PDF]

Vnitřní lékařství, 2018
Idiopathic inflammatory myopathies form a heterogeneous group of acquired inflammatory diseases afflicting striated muscles. The disease is frequently accompanied by systemic and organ involvement. Dermatomyositis, polymyositis, cancer associated myositis, immune mediated necrotizing myopathy, myositis in overlap syndromes, juvenile myositis and ...
openaire   +2 more sources

Neurological complications of immune checkpoint inhibitors: what happens when you \u27take the brakes off\u27 the immune system. [PDF]

, 2018
Patients with advanced malignancies treated with immune checkpoint inhibitors are at increased risk for developing immune-related neurological complications.
Dalakas, Marinos
core   +1 more source

Miopatia induzida pelo vírus influenza A (H1N1): uma complicação extrapulmonar importante [PDF]

, 2012
Universidade Federal de São Paulo (UNIFESP), Escola Paulista de Medicina (EPM) Department of Neurology and NeurosurgeryUNIFESP, EPM, Department of Neurology and ...
Oliveira, Acary Souza Bulle
core   +2 more sources