Results 151 to 160 of about 1,622,130 (371)

Rituximab in the treatment of inflammatory myopathies: a review [PDF]

, 2017
Several uncontrolled studies have encouraged the use of rituximab (RTX) in patients with myositis. Unfortunately, the first placebo-phase trial to assess the efficacy of RTX in refractory myositis did not show a significant difference between the two ...
Fasano, S, Gordon, P, Hajji, R, Isenberg, DA, Loyo, E   +4 more
core  

Clinical, manometric, genetic, and histologic associations in pediatric intestinal pseudo‐obstruction: A case series

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Pediatric intestinal pseudo‐obstruction (PIPO) is a severe bowel motility disorder characterized by impaired propulsion of gastrointestinal contents without mechanical obstruction. PIPO encompasses congenital and acquired disorders, including neuropathies, myopathies, and mesenchymopathies.
Sharon Wolfson, Myra Butrviengpunt, Naomi Tjaden, Alain J. Benitez, Archana S. Kota, Jennifer Webster, Prasanna Kapavarapu, Hayat Mousa, Robert O. Heuckeroth   +8 more
wiley   +1 more source

Genetic association study of NF-κB genes in UK Caucasian adult and juvenile onset idiopathic inflammatory myopathy [PDF]

, 2012
Treatment-resistant muscle wasting is an increasingly recognized problem in idiopathic inflammatory myopathy (IIM). TNF-α is thought to induce muscle catabolism via activation of nuclear factor-kappa B (NF-κB). Several genes share homology with the NF-κB
Betteridge, Z, Chinoy, H, Cooper, RG, Fertig, N, Gunawardena, H, Li, CK, McHugh, NJ, Oddis, CV, Ollier, WE, Platt, H, UK Adult Onset Myositis Immunogenetic Consortium and UK Juvenile, Varsani, H, Wedderburn, LR   +12 more
core  

Autoantibody signatures in children with celiac disease, juvenile idiopathic arthritis, and polyautoimmunity

JPGN Reports, EarlyView.
Abstract Objective To determine if multiplex autoantibody arrays can identify novel biomarker signatures in children with one or multiple autoimmune diseases (polyautoimmunity). Methods Plasma collected from children (18 years or younger) in the Boston Children's Hospital Precision Link Biobank for Health Discovery between January 2007 and June 2021 ...
Nan Du, Denis Chang, Madison Wong, Jay R. Thiagarajah, Erin Janssen, Lauren A. Henderson, Krishnan Raghunathan, Jocelyn A. Silvester   +7 more
wiley   +1 more source

Imaging assessment of calcinosis in juvenile dermatomyositis: a narrative review

Pediatric Rheumatology Online Journal
Calcinosis is a severe manifestation of juvenile and adult idiopathic inflammatory myopathies, which can lead to pain, limited range of motion, disfigurement, and infection.
Belina Y. Yi, Jessica Perfetto, Evin Rothschild, Kelly Rouster-Stevens, Amanda Robinson, Kathryn Cook, Delaney D. Ding, Andrea Eagle Child, Ovgu Kul Cinar, Barbara Limbach, Charalampia Papadopoulou, Lesley Ann Saketkoo, Adam Schiffenbauer, Heinrike Schmeling, Antonia Valenzuela, Susan Shenoi, Dawn M. Wahezi, for the CARRA JDM Calcinosis workgroup   +17 more
doaj   +1 more source

Gastrointestinal strictures in a pediatric patient with Satoyoshi syndrome

JPGN Reports, EarlyView.
Abstract We present a novel case of gastrointestinal strictures in a young girl with Satoyoshi syndrome (SS), highlighting multi‐system features of alopecia universalis, painful muscle cramps with dystonia, aberrant growth velocity, and skeletal abnormalities.
Katherine (Tusia) Pohoreski, Gary Galante, Kiera Pajunen, Marie‐Anne Brundler, Samarjeet Bhandal, Iwona Wrobel   +5 more
wiley   +1 more source

FRI0398 Inflammatory myopathies with camptocormia or dropped head syndrome are associated scleromyositis with late onset and delayed diagnosis [PDF]

, 2017
Luc Pijnenburg, F. Maurier, Nicolas Poursac, Marion Couderc, N. Vernier, Isabelle Guichard, Jérémie Sellam, Jean Sibilia, Alain Meyer   +8 more
openalex   +1 more source

Muscle Ultrasound Echo Intensity Detects Insulin Resistance Before Changes in HbA1c or Fasting Glucose, Independent of BMI

Journal of Ultrasound in Medicine, EarlyView.
Objectives To quantify the association between skeletal muscle echo intensity (MEI), measured by ultrasound, and clinical markers of insulin resistance and glycemic control, and evaluate MEI's diagnostic accuracy in identifying insulin resistance. Methods In this cross‐sectional study, 20 adults with obesity (mean body mass index [BMI] 34.4 ± 2.6 kg/m2,
Steven B. Soliman, Jacob E. Leuteneker, Olivia K. Chugh, Tao Zhang, Becca Tuska, Thomas Rode, Maria J. Sanchez, Eric D. Buras, Jeffrey F. Horowitz   +8 more
wiley   +1 more source

FRI0385 Joint manifestations in patients diagnosed with idiopathic inflammatory myopathy: multicenter registry [PDF]

, 2017
DC Hernández Flόrez, L. Valor, Julia Romero Martínez, Beatriz Joven, Laura Nuño, Carmen Larena, I. Llorente, C. Barbadillo, Paloma García de la Peña, L. Ruiz, Henry Moruno, Tatiana Cobo‐Ibáñez, Raquel Almodóvar, L. Lojo, M.J. García, FJ López-Longo   +15 more
openalex   +1 more source

Fetal Ductal Constriction, Pulmonary Hypertension and Atrial Septum Mobility

Journal of Ultrasound in Medicine, EarlyView.
Objectives Fetuses with ductal constriction (FDC), pulmonary hypertension and right ventricular overload after maternal exposure to PGE2 inhibitors—nonsteroidal anti‐inflammatory drugs (NSAIDs) or polyphenols (PF)—have increased septum primum excursion index (SPEI), the ratio between maximal septum primum displacement and left atrial diameter.
Paulo Zielinsky, Polyanna Henriques, Pedro Van Der Sand, Maria Antonia Saldanha, Gabriela Macelaro, Joana Nicoloso   +5 more
wiley   +1 more source