Results 141 to 150 of about 15,772 (257)

Preliminary nomogram model for predicting respiratory failure of patients with idiopathic inflammatory myopathies. [PDF]

Sci Rep
Huo X, Yang Y, Wei C, Huang X, Lin J, Lin Y.   +5 more
europepmc   +1 more source

The mitochondrial‐targeted antioxidant SkQ1 prevents skeletal muscle mitochondrial‐apoptotic but not necroptotic signalling during ovarian cancer

The Journal of Physiology, EarlyView.
Abstract figure legend An evaluation of the degree to which mitochondrial hydrogen peroxide emission (mH2O2)‐mediated apoptotic and necroptotic signalling contributes to skeletal muscle atrophy in an orthotopic epithelial ovarian cancer (EOC) model. To determine whether attenuating mH2O2 could prevent regulated cell death signalling and mitigate muscle
Shahrzad Khajehzadehshoushtar, Luca J. Delfinis, Fasih A. Rahman, Madison C. Garibotti, Shivam Gandhi, Aditya N. Brahmbhatt, Brooke A. Morris, Bianca Garlisi, Sylvia Lauks, Caroline Aitken, Leslie Ogilvie, Zhu‐Xu Zhang, Jeremy A. Simpson, Joe Quadrilatero, Jim Petrik, Christopher G. R. Perry   +15 more
wiley   +1 more source

Correction: Subclinical cardiac dysfunction in idiopathic inflammatory myopathies: the role of global longitudinal strain. [PDF]

Clin Exp Med
Romano S, Sartorio A, Pont CD, Segatta F, Piazzola M, Vicardi M, Cominacini M, Aldegheri F, Bixio R, Viapiana O.   +9 more
europepmc   +1 more source

Mechanism‐Informed Pharmacotherapy Optimization and Deprescribing: A Redox–Mitochondrial Framework

Pharmacology Research &Perspectives, Volume 14, Issue 5, October 2026.
From cumulative drug burden to mitochondrial stress and functional decline. The graphical abstract summarizes the central concept of the review, illustrating how cumulative pharmacotherapy exposure may contribute to redox–mitochondrial stress and thereby reduce biological and functional resilience.
Boštjan Martinc
wiley   +1 more source

The Role of C/EBP-Homologous Protein in Idiopathic Inflammatory Myopathies. [PDF]

J Cell Mol Med
Sciacco M, Ciscato P, Bertolasi L, Guttuso M, Corti S, Mattinzoli D, Ikeata M, Castellano G, Comi GP, Zanotti S.   +9 more
europepmc   +1 more source

Diagnostic Odyssey of Atypical Long‐Chain 3‐Hydroxyacyl‐CoA Dehydrogenase Deficiency (LCHADD) Explained by Three Allelic Products From Two Pathogenic Variants

American Journal of Medical Genetics Part A, Volume 200, Issue 9, Page 2128-2135, September 2026.
ABSTRACT Long‐chain 3‐hydroxyacyl‐CoA dehydrogenase deficiency (LCHADD) is an autosomal recessive mitochondrial defect of long‐chain fatty acid β‐oxidation, caused by biallelic pathogenic variants in HADHA or HADHB. We report a 22‐year‐old male with an atypically mild presentation of LCHADD who was referred to the Undiagnosed Diseases Network (UDN ...
Yutaka Furuta, Lynette C. Rives, T. Andrew Burrow, Thomas A. Cassini, Rory J. Tinker, Amy K. Robertson, Kimberly M. Ezell, Rizwan Hamid, Joy D. Cogan, John A. Phillips III   +9 more
wiley   +1 more source

Elevated sST2 associates with cardiac involvement and declines after treatment in newly diagnosed patients with idiopathic inflammatory myopathies. [PDF]

Arthritis Res Ther
Hanna B, Lundberg IE, Ekwall AH, Glinatsi D, Sakiniene E, Hu Z, Pullerits R, Jin T.   +7 more
europepmc   +1 more source

Pregnancy outcomes in idiopathic inflammatory myopathies: a Portuguese multicentre study. [PDF]

Front Med (Lausanne)
Lopes AR, Teodósio Chícharo A, Campanilho-Marques R, Abreu C, Rodrigues SD, Santos I, Paramés F, Barreira SC, Pulido-Valente M, Pinto L, Cruz-Machado AR, Capela S.   +11 more
europepmc   +1 more source

Mechanisms and Predisposing Conditions for Statin‐Induced New‐Onset Type 2 Diabetes Mellitus: A Paradox Relative to Their Pleiotropic Metabolic Effects

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 5, September 2026.
The primary function of statins is to inhibit cholesterol synthesis, which contributes to their antidiabetic effects. However, the majority of the diabetic effects of statins are due to inhibition of isoprenoid synthesis. Atorvastatin, simvastatin and rosuvastatin possess the most pronounced diabetogenic properties. In contrast, lovastatin, fluvastatin,
Ali Nosrati Andevari, Mohsen Koolivand
wiley   +1 more source

Subclinical cardiac dysfunction in idiopathic inflammatory myopathies: the role of global longitudinal strain. [PDF]

Clin Exp Med
Romano S, Sartorio A, Pont CD, Segatta F, Piazzola M, Vicardi M, Cominacini M, Aldegheri F, Bixio R, Viapiana O.   +9 more
europepmc   +1 more source