Results 161 to 170 of about 1,587,143 (318)

Skeletal Muscle Fibers Express Major Histocompatibility Complex Class II Antigens Independently of Inflammatory Infiltrates in Inflammatory Myopathies [PDF]

, 2001
Pernilla Englund, Eva Lindroos, Inger Nennesmo, Lars Klareskog, Ingrid E. Lundberg   +4 more
openalex   +1 more source

European Society for the Study of Coeliac Disease 2025 Updated Guidelines on the Diagnosis and Management of Coeliac Disease in Adults. Part 1: Diagnostic Approach

United European Gastroenterology Journal, EarlyView.
Infographic. This infographic summarizes the diagnostic approach to CeD in adults, including initial serological testing, histological confirmation, criteria for a no‐biopsy diagnosis, seronegative CeD, potential CeD, and the role of gluten challenge. Source: Authors' own creation (based on current clinical guidelines).
Abdulbaqi Al‐Toma, Fabiana Zingone, Federica Branchi, Annalisa Schiepatti, Georgia Malamut, Cristina Canova, Isabella Rosato, Honoria Ocagli, Nick Trott, Luca Elli, Alina Popp, Carmen Gianfrani, Renata Auricchio, Andra Neefjes‐Borst, David S. Sanders, Christophe Cellier, Chris J. Mulder, Gerd Bouma, Knut E. A. Lundin, Ludvig M. Sollid, Michael Schumann   +20 more
wiley   +1 more source

Frequency and risk factors for tail injuries in UK dogs under primary veterinary care

Veterinary Record, EarlyView.
Abstract Background Tail injuries in dogs can severely impact welfare and pose clinical challenges. This study aimed to describe the annual incidence and clinical management of tail injury in UK dogs under primary care and identify risk factors. Methods A nested case‒control design was used within a cohort of dogs under primary care in the UK in 2019 ...
Camilla Pegram, Dan G. O'Neill, Alexandra Edwards, David B. Church, Dave C. Brodbelt   +4 more
wiley   +1 more source

Clinical and pathological findings in giraffes (Giraffa camelopardalis) with arterial thrombotic disease

Veterinary Record Case Reports, EarlyView.
Abstract Two adult female giraffes (Giraffa camelopardalis) from separate facilities were diagnosed with arterial thrombotic disease. The first giraffe presented with acute severe unilateral hindlimb paralysis. Infrared thermography revealed a marked temperature decrease compared to the contralateral limb starting from the mid‐thigh region, indicative ...
Pierre Huberdeau, Benjamin Lamglait, Sylvie Laidebeure, Pierre Hélie, Shannon T. Ferrell, Marion Desmarchelier, Emilie L. Couture, Alexis Lécu   +7 more
wiley   +1 more source

miR‐140‐5p Overexpression Contributes to Oxidative Stress and Mitochondrial Dysfunction in Hutchinson‐Gilford Progeria Syndrome Fibroblasts Through NRF2 Pathway

Aging Cell, EarlyView.
This study identifies a novel molecular mechanism involving miR‐140‐5p that contributes to the pathogenesis of HGPS. By decreasing NRF2 expression, miR‐140‐5p overexpression results in downregulation of the NRF2/KEAP1/HO‐1 antioxidant pathway in HGPS fibroblasts, leading to increased oxidative stress and mitochondrial dysfunction, two hallmarks of ...
Léa Toury, Diane Frankel, Sara Nael, Mario Abaji, Léa Le Goff, Marie Basset, Coraline Airault, Bertrand Vernay, Elva María Novoa‐del‐Toro, Catherine Bartoli, Anaïs Baudot, Frederique Magdinier, Elise Kaspi, Patrice Roll   +13 more
wiley   +1 more source

AB0815 CLINICAL PHENOTYPE AND ANTIBODY CORRELATIONS USING IMMUNOPRECIPITATION IN INDIAN PATIENTS WITH IDIOPATHIC INFLAMMATORY MYOPATHIES FROM THE MYOCITE COHORT [PDF]

, 2023
Aravinthan Loganathan, Alex Rudge, Hui Lu, Elizabeth Bowler, Fionnuala K McMorrow, N. Ravichandran, Anamika Kumari Anuja, V. Agarwal, Latika Gupta, Neil McHugh, Sarah Tansley   +10 more
openalex   +1 more source

Recumbent FES‐Cycling Exercise Improves Muscle Performance and Ambulation Capacity in Hospitalized Patients: A Randomized Controlled Trial

Artificial Organs, EarlyView.
Both groups received the usual routine hospital care. Beyond usual care, the intervention group received the high‐intensity, low‐volume FES‐cycling exercise protocol. Study highlights are as follows: (1) High‐intensity, low‐volume FES‐cycling exercise increased strength, power, and neuromuscular efficiency. (2) Ambulation capacity improved threefold in
Murillo Frazão, Fábio de Lima Martins, Gerson Cipriano Jr   +2 more
wiley   +1 more source

LCN2‐ACOD1 Signalling Affects the Post‐Injury Regeneration of Skeletal Muscle Through Mediating Ferroptosis

Cell Proliferation, EarlyView.
LCN2 mediates the suppression of C2C12 myoblast proliferation and myotube formation via erastin‐induced ferroptosis. Mechanistically, the LCN2‐ACOD1 axis regulates skeletal muscle growth via mitochondria‐associated ferroptosis, providing a theoretical basis for the prevention and therapy of muscle‐related diseases.
Xiaojing Hao, Hongwei Shi, Di Wu, Rui Liang, Tong Zhao, Wen Sun, Yue Wang, Xiuju Yu, Xiaomao Luo, Yi Yan, Jiayin Lu, Haidong Wang, Juan Wang   +12 more
wiley   +1 more source

A matter arising: When should inflammatory and autoimmune rheumatic diseases be considered ‘early’?

European Journal of Clinical Investigation, EarlyView.
Timely recognition of inflammatory and autoimmune rheumatic diseases (IARDs) is important to optimize the early diagnosis with tailored interventions and possible prevention of irreversible organ damage. This narrative review provides an update by summarizing the advances in identifying the early stages of rheumatoid arthritis, systemic sclerosis and ...
Elvis Hysa, Emanuele Gotelli, Carmen Pizzorni, Sabrina Paolino, Alberto Sulli, Vanessa Smith, Rosanna Campitiello, Maurizio Cutolo   +7 more
wiley   +1 more source

Correlation of Clinicoserologic and Pathologic Classifications of Inflammatory Myopathies

, 2012
Carla Fernandez, Nathalie Bardin, A. Maues de Paula, Emmanuelle Salort-Campana, A. Benyamine, J. Franques, N. Schleinitz, Pierre‐Jean Weiller, Jean Pouget, Jean‐François Pellissier, Dominique Figarella‐Branger   +10 more
openalex   +2 more sources