Results 171 to 180 of about 1,587,143 (318)

Frozen in Addiction: A New Wave of Drug‐Induced Movement Disorders?

open access: yes
Movement Disorders, EarlyView.
Christos Ganos   +12 more
wiley   +1 more source

Equine botulism

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Botulism is a severe and often fatal disease in equine patients worldwide. Clostridium botulinum is a ubiquitous soil organism which produces a potent neurotoxin resulting in neuromuscular blockade and flaccid paralysis in affected animals. Definitive diagnosis is often impractical or impossible, leading to diagnosis and treatment based on ...
Kali Slavik   +2 more
wiley   +1 more source

Collagen XV preserves heart function and protects from pathological remodelling after myocardial infarction

open access: yesThe FEBS Journal, EarlyView.
The damage caused by myocardial infarction is exacerbated in the absence of collagen XV and leads to pathological remodelling and more severe left ventricle dysfunction (left panel) compared with the wild‐type littermates. These changes are accompanied by a wide‐ranging impact, including phenotypical (middle panel) and molecular (right panel) changes ...
Sanna‐Maria Karppinen   +15 more
wiley   +1 more source

Combating muscle atrophy: emerging therapeutic targets that are fiber‐type‐specific

open access: yesThe FEBS Journal, EarlyView.
Inflammation, denervation or decreased insulin signaling activate proteolysis and cause muscle wasting. Pathological conditions like obesity and DMD can also exacerbate atrophy via PGD2–RhoA–ROCK2 signaling. In contrast, exercise, dietary interventions, and pharmacological agents can activate Ca2+/calcineurin–NFAT and AMPK–PGC‐1α–MEF pathways ...
Samrat Chakraborty   +2 more
wiley   +1 more source

Human leukocyte antigen in Japanese patients with idiopathic inflammatory myopathy

open access: green, 2019
Hiroshi Furukawa   +27 more
openalex   +2 more sources

Prevalence of vasculitis, systemic lupus erythematosus, rheumatoid arthritis, systemic sclerosis, idiopathic inflammatory myopathies and spondyloarthritis in Australia: a systematic review and meta‐analysis

open access: yesInternal Medicine Journal, EarlyView.
ABSTRACT Background Systemic autoimmune rheumatic diseases (SARDs), including vasculitis, systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), systemic sclerosis (SSc), idiopathic inflammatory myopathies (IIM), spondyloarthritis (SpA), Sjogrens disease (SjD) and mixed connective tissue disease (MCTD), are rare but associated with substantial ...
L. Roper   +6 more
wiley   +1 more source

Osmolytes as mediators of the muscle tissue’s responses to inflammation : emerging regulators of myositis with therapeutic potential [PDF]

open access: yes, 2017
Chronic inflammation of skeletal muscle tissues termed myositis is associated with inherited muscular dystrophy and with acquired inflammatory myopathy.
De Paepe, Boel
core   +1 more source

Amyloidosis for the Gastroenterologist: A Comprehensive Systematic Review of Diagnosis and Management of Gastrointestinal Manifestations

open access: yesJournal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Background Amyloidosis is a rare, multisystem disorder characterized by extracellular deposition of misfolded protein fibrils. Gastrointestinal (GI) amyloidosis is uncommon but under‐recognized due to nonspecific symptoms, but early diagnosis is critical to improve quality of life and prognosis.
Myo Jin Tang   +3 more
wiley   +1 more source

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