Results 191 to 200 of about 18,649 (278)

Muscle Ultrasound in Inclusion Body Myositis: Integrating Qualitative and Quantitative Approaches With Clinical and MRI Findings

Muscle &Nerve, Volume 74, Issue 1, Page 131-138, July 2026.
ABSTRACT Introduction/Aims Inclusion body myositis (IBM) is an inflammatory myopathy with an insidious onset, often making diagnosis challenging. Although neuroimaging has recently been included in diagnostic criteria, the role of muscle ultrasound—despite being a rapid and cost‐effective tool—in IBM has been less extensively characterized.
Giuseppe Di Pietro, Pietro Falco, Rocco Costanzo, Eleonora Galosi, Gianfranco De Stefano, Enrico Evangelisti, Antonio Lauletta, Caterina Leone, Daniel Litewczuk, Giulia Di Stefano, Andrea Truini, Matteo Garibaldi   +11 more
wiley   +1 more source

Sit to stand and timed up and go in idiopathic inflammatory myopathies. [PDF]

Sci Rep
Chandra T, Silva RL, Keret S, Li R, Balasubramani GK, Riaz R, Sharma A, Wilkerson J, Ascherman DP, Oddis CV, Moghadam-Kia S, Aggarwal R.   +11 more
europepmc   +1 more source

Unraveling the spatial landscape of dystrophinopathies: a transcriptomic approach to Becker and Duchenne muscular dystrophies

The Journal of Pathology, Volume 269, Issue 3, Page 363-380, July 2026.
Abstract Dystrophinopathies are caused by pathogenic variants in the DMD gene, resulting in partial (Becker) or complete loss (Duchenne) of dystrophin. Becker (BMD) and Duchenne muscular dystrophy (DMD) are characterized by progressive muscle wasting, fatty replacement, fibrosis, and loss of function.
Laura GM Heezen, Qirong Mao, Stefan Nicolau, Claudio Novella Rausell, Julia van der Weerd, Jan Kueckelhaus, Rasya Gokul Nath, Jordi Diaz‐Manera, Hermien E Kan, Erik H Niks, Maaike van Putten, Annemieke Aartsma‐Rus, Kevin M Flanigan, Ahmed Mahfouz, Pietro Spitali   +14 more
wiley   +1 more source

Treatment Algorithms for Inflammatory Myopathies in Adults: from Guidelines to Clinical Practice. [PDF]

Curr Treatm Opt Rheumatol
Selva-O'Callaghan A, Trallero-Araguás E, Gil-Vila A, Matas-Garcia A, Edo C, Milisenda J, Pinal-Fernández I.   +6 more
europepmc   +1 more source

Myosin Post‐Translational Modifications Associated With Critical Illness Myopathy

Acta Physiologica, Volume 242, Issue 7, July 2026.
ABSTRACT Background Critical illness myopathy is a common and devastating consequence of critical care, causing dramatic loss of muscle mass and function in intensive care unit patients. Functional deficits often exceed the loss in muscle mass and myosin content.
Fernando Ribeiro, Bruno Di Geronimo, Nicola Cacciani, Anna Widgren, Yvette Hedström, Anselmo S. Moriscot, Peter M. Kasson, Shina C. L. Kamerlin, Jonas Bergquist, Lars Larsson   +9 more
wiley   +1 more source

Preliminary ultrastructural analysis suggests phenotype-specific myofiber alterations in idiopathic inflammatory myopathies. [PDF]

Sci Rep
Aguilar-Vazquez A, Juarez-Gomez C, Gonzalez-Gauna E, Medrano-Ramirez G, Vargas-Cañas S, Vargas-Guerrero A, Gutiérrez-Hernández JM, Toriz G, Gomez-Rios CA, Medina-Preciado JD, Chavarria-Avila E, Martin-Marquez BT, Pizano-Martinez O, Martinez-Garcia EA, Perez-Vazquez F, Sandoval-Garcia F, Salazar-Paramo M, Rubio-Arellano ED, Becerra-Jimenez J, Garcia-Ordoñez G, Gaspar-Ruiz A, Ramos-Hernandez A, Cabrera-Lopez M, Llamas-Garcia A, Vazquez-Del Mercado M.   +24 more
europepmc   +1 more source

Drugs that act on both G protein‐coupled receptors (GPCRs) and kinases: potentiation of effects, side effects and general aspects of drug pleiotropy

British Journal of Pharmacology, Volume 183, Issue 13, Page 3471-3483, July 2026.
Abstract Background A drug designed for a specific target often interacts with multiple targets, either unintentionally or as part of its intended mechanism of action. This has been called pharmacological pleiotropy or polypharmacology. There are key endogenous ligands such as ATP, GABA and glutamate that act on various proteins in humans. Furthermore,
Hampus Ljunggren, Aleksandr Sokolov, Flavio Ballante, Robert Fredriksson, Francisco Lagunas‐Rangel, Alexander S. Hauser, Stefan Knapp, Jörgen Jonsson, Helgi B. Schiöth   +8 more
wiley   +1 more source

Characterization of Antinuclear, Myositis-Specific, and Myositis-Associated Antibodies in a Large Sample of Patients With Idiopathic Inflammatory Myopathies. [PDF]

Cureus
Barbosa RA, Shinjo SK.
europepmc   +1 more source

Multi‐Omics Landscape of Paraspinal Muscles in Spinal Muscular Atrophy With Scoliosis

Journal of Cellular and Molecular Medicine, Volume 30, Issue 13, July 2026.
ABSTRACT Most spinal muscular atrophy (SMA) patients develop severe scoliosis by late adolescence. Given that the paraspinal muscles—particularly the multifidus—are indispensable for maintaining spinal stability, their site‐specific multi‐omics characteristics in SMA remain insufficiently defined. Herein, integrated multi‐omics sequencing was performed
Zhen Wang, Junduo Zhao, Xu'an Huang, Weiyun Chen, Jianxiong Shen   +4 more
wiley   +1 more source

Epidemiology of Dermatomyositis and Other Idiopathic Inflammatory Myopathies in Northern Spain. [PDF]

Biomedicines
Corrales-Selaya C, Prieto-Peña D, Martínez-López D, Benavides-Villanueva F, Blanco R.   +4 more
europepmc   +1 more source