Results 201 to 210 of about 1,622,130 (371)

Neuromuscular and neuromechanical assessments of respiratory performance in the mdx mouse model of Duchenne muscular dystrophy across the natural history of disease

Experimental Physiology, EarlyView.
Abstract Duchenne muscular dystrophy (DMD) is a severe life‐limiting X‐linked neuromuscular disorder characterised by progressive skeletal muscle degeneration and respiratory failure. The mdx mouse, lacking dystrophin, is the most widely used preclinical model of DMD, yet the trajectory of respiratory dysfunction in this model remains incompletely ...
Michael N. Maxwell, Christopher G. Wilson, Mai K. Elmallah, Federica Trucco, Ken D. O'Halloran   +4 more
wiley   +1 more source

The Role of C/EBP-Homologous Protein in Idiopathic Inflammatory Myopathies. [PDF]

J Cell Mol Med
Sciacco M, Ciscato P, Bertolasi L, Guttuso M, Corti S, Mattinzoli D, Ikeata M, Castellano G, Comi GP, Zanotti S.   +9 more
europepmc   +1 more source

Inflammatory Myopathies – Experience from Our Center Over a Three-Year Period

Juraga, Valentina, Barić, Anastasija, Ponjavić, Nikolina, Mrsić, Fanika, Kovačić, Ana Marija, Vukosav, Vinka, Markeljević, Jasenka   +6 more
openalex   +1 more source

“Idiopathic inflammatory myopathies and the lung.” Jean-Christophe Lega, Quitterie Reynaud, Alexandre Belot, Nicole Fabien, Isabelle Durieu and Vincent Cottin.Eur Respir Rev2015; 24: 216–238. [PDF]

, 2015
Jean‐Christophe Lega, Quitterie Reynaud, Alexandre Bélot, Nicole Fabien   +3 more
openalex   +1 more source

Canonical and non‐canonical functions of proteins regulating mitochondrial dynamics in mammalian physiology

The Journal of Physiology, EarlyView.
Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney, Vincent Marcangeli, Krystel Desjardins, Shima Taherkhani, Gilles Gouspillou   +4 more
wiley   +1 more source

Prevalence and functional characterization of anti-interferon autoantibodies in inflammatory myopathies. [PDF]

Rheumatology (Oxford)
Pinal-Fernandez I, Rosen LB, Gomez-Vazquez JL, Casal-Dominguez M, Lee S, Milisenda JC, Pak K, Solanich X, Holland SM, Selva-O'Callaghan A, Mammen AL.   +10 more
europepmc   +1 more source

The mitochondrial‐targeted antioxidant SkQ1 prevents skeletal muscle mitochondrial‐apoptotic but not necroptotic signalling during ovarian cancer

The Journal of Physiology, EarlyView.
Abstract figure legend An evaluation of the degree to which mitochondrial hydrogen peroxide emission (mH2O2)‐mediated apoptotic and necroptotic signalling contributes to skeletal muscle atrophy in an orthotopic epithelial ovarian cancer (EOC) model. To determine whether attenuating mH2O2 could prevent regulated cell death signalling and mitigate muscle
Shahrzad Khajehzadehshoushtar, Luca J. Delfinis, Fasih A. Rahman, Madison C. Garibotti, Shivam Gandhi, Aditya N. Brahmbhatt, Brooke A. Morris, Bianca Garlisi, Sylvia Lauks, Caroline Aitken, Leslie Ogilvie, Zhu‐Xu Zhang, Jeremy A. Simpson, Joe Quadrilatero, Jim Petrik, Christopher G. R. Perry   +15 more
wiley   +1 more source

Sit to stand and timed up and go in idiopathic inflammatory myopathies. [PDF]

Sci Rep
Chandra T, Silva RL, Keret S, Li R, Balasubramani GK, Riaz R, Sharma A, Wilkerson J, Ascherman DP, Oddis CV, Moghadam-Kia S, Aggarwal R.   +11 more
europepmc   +1 more source

14‐3‐3 proteins: Regulators of cardiac excitation–contraction coupling and stress responses

The Journal of Physiology, EarlyView.
Abstract figure legend 14‐3‐3 protein interactions in cardiac regulation. Schematic representation of 14‐3‐3 binding partners in excitation–contraction coupling, transcriptional regulation/development and stress response pathways. Asterisks indicate targets where the exact 14‐3‐3 binding site is unknown.
Heather C. Spooner, Rose E. Dixon
wiley   +1 more source

Factors associated with interstitial lung disease among patients with idiopathic inflammatory myopathies. [PDF]

Rheumatology (Oxford)
Wilkerson JC, Miller FW, Bridge MF, Larson GJ, Schurman SH, Garantziotis S, Farhadi PN, Schiffenbauer A, Rider LG.   +8 more
europepmc   +1 more source