Results 271 to 280 of about 1,622,130 (371)

Is Ferroptosis the Mechanistic Bridge Connecting Iron Dysregulation to Muscle Wasting and Functional Decline in Aging?

Aging Cell, Volume 25, Issue 2, February 2026.
This work proposes ferroptosis as a mechanistic driver of age‐related muscle dysfunction, whereby iron dyshomeostasis and impaired antioxidant capacity promote lipid peroxidation, and eventually trigger ferroptosis, leading to muscle wasting, and ultimately contributing to weakness and functional decline with aging.
Rola S. Zeidan, Simon Reinhard, Anna Picca, Emanuele Marzetti, Christiaan Leeuwenburgh, James F. Collins, Stephen D. Anton   +6 more
wiley   +1 more source

Nuclear medicine imaging in idiopathic inflammatory myopathies

European Journal of Rheumatology, 2019
Thomas Nadin, Mohammed Akil, Manu Shastry, Michael Hughes   +3 more
doaj   +1 more source

Barriers and facilitators to exercise in people with idiopathic inflammatory myopathies: a qualitative study. [PDF]

BMC Rheumatol
Li N, Frade S, Roper L, Parker MJ, Youssef P, Nikpour M.   +5 more
europepmc   +1 more source

Comparative multi‐omics in female mice reveals tissue‐specific vulnerabilities to chronic alcohol intake

Alcohol, Clinical and Experimental Research, Volume 50, Issue 2, February 2026.
Using mice, we applied multi‐omics to compare liver and skeletal muscle after chronic alcohol consumption. The liver responded more strongly across genes, proteins, and metabolites, with a lowered PC:PE ratio. Muscle showed inflammation, extracellular matrix activation, impaired mitochondrial energetics, and an elevated PC:PE ratio. Lipidomics affected
Craig R. G. Willis, Muni Swamy Ganjayi, Austin M. Brown, Samantha E. Moser, Nathaniel J. Szewczyk, Brian C. Clark, Cory W. Baumann   +6 more
wiley   +1 more source

Associations between TNF gene promoter variants (rs361525, rs1800629, rs1799964, rs1799724) and the clinical course of idiopathic inflammatory myopathies. [PDF]

Sci Rep
Padjas A, Mikołajczyk-Korona A, Dziedzic R, Dziedzina S, Sanak M, Bazan-Socha S, Bazan JG, Zaręba L, Korkosz M, Kosałka-Węgiel J.   +9 more
europepmc   +1 more source

The Vitamin D Receptor Agonist BXL-01-0029 as a Potential New Pharmacological Tool for the Treatment of Inflammatory Myopathies

, 2013
Luigi Di Luigi, Mariangela Sottili, Cristina Antinozzi, Gabriella Barbara Vannelli, Francesco Romanelli, Valeria Riccieri, Guido Valesini, Andrea Lenzi, Clara Crescioli   +8 more
openalex   +2 more sources

Pharmacogenomics of Thiopurine Drugs: A Bench‐To‐Bedside Success Story in Thailand

Clinical and Translational Science, Volume 19, Issue 2, February 2026.
ABSTRACT Thiopurine drugs are the cornerstone treatment for many diseases such as acute lymphoblastic leukemia (ALL), organ rejection, inflammatory bowel disease (IBD), systemic lupus erythematosus (SLE), rheumatoid arthritis (RA) and other autoimmune diseases.
Mohitosh Biswas, Shobana John, Murshadul Alam Murad, Chonlaphat Sukasem   +3 more
wiley   +1 more source

Nutritional interventions as modulators of the disease activity for idiopathic inflammatory myopathies: a scoping review [PDF]

Abril I. Sánchez‐Rosales, Juan Gabriel Posadas-Calleja, Aurora E. Serralde‐Zúñiga, Gabriela Quiroz‐Olguín   +3 more
openalex   +1 more source

Novel biomarkers of changes in muscle mass or muscle pathology [PDF]

, 2017
Arvanitidis, Athanasios
core  

EAN 2024 Guideline on the Diagnostic Approach to Oligo/Asymptomatic HyperCKemia

European Journal of Neurology, Volume 33, Issue 2, February 2026.
ABSTRACT Background Recent epidemiological studies on the general population reveal that up to 1.3% have oligo/asymptomatic hyperCKemia. Objective This guideline aims to provide updated, evidence‐based recommendations on investigating persons older than 18 years.
T. Kyriakides, K. Aleksovska, C. Angelini, Z. Argov, K. G. Claeys, M. de Visser, M. FIlosto, I. Jovanovic, A. Kostera‐Pruszczyk, M. J. Molnar, S. Sacconi, J. Schaefer, G. Siciliano, J. J. Vilchez, B. Schoser, A. Toscano   +15 more
wiley   +1 more source