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THERAPY OF INFLAMMATORY MYOPATHY
Rheumatic Disease Clinics of North America, 1994The management of the muscular and extramuscular manifestations of the inflammatory myopathies remains a challenge for the practicing rheumatologist. Although corticosteroids remain the first line of therapy, their side effects often limit their usefulness.
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1985
Inflammatory myopathies are those in which muscle cell injury is largely attributable to an inflammatory reaction and inflammatory cells are invariably present in the muscle. The inflammatory response may be elicited by viral, bacterial or parasitic infestation of muscle.
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Inflammatory myopathies are those in which muscle cell injury is largely attributable to an inflammatory reaction and inflammatory cells are invariably present in the muscle. The inflammatory response may be elicited by viral, bacterial or parasitic infestation of muscle.
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Idiopathic Inflammatory Myopathies
ContinuumThis article describes the various idiopathic inflammatory myopathies, including their clinical presentation, pathogenesis, diagnosis, and treatments. While many disorders fall under this umbrella, this article focuses on dermatomyositis, antisynthetase syndrome, immune-mediated necrotizing myopathy, polymyositis, and overlap syndrome.The diagnosis of ...
Mohammad Kian, Salajegheh +1 more
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Inflammatory myopathies and lymphoma
Journal of the Neurological Sciences, 2016The inflammatory myopathies comprise a group of immune-mediated muscle diseases. Lymphoma is a term for a variety of lymphatic system malignancies. Autoimmune diseases and lymphoproliferative malignancies share a complex bidirectional relationship. A causal relationship between inflammatory mypathies and lymphoma has not been established. The diagnosis/
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Inflammatory and Toxic Myopathy
Seminars in Neurology, 2013Although muscle diseases are relatively rare, several treatable myopathies must be recognized by the clinician to maximize the possibility of restoring strength in affected patients. The inflammatory myopathies, including polymyositis, dermatomyositis, inflammatory necrotizing myopathy, and myositis in association with mixed connective tissue disease ...
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Immunopathogenesis of inflammatory myopathies
Annals of Neurology, 1995Immune-mediated mechanisms appear to play a primary role in the pathogenesis of polymyositis (PM) and dermatomyositis (DM). The serum of patients with active DM has high levels of circulating complement fragments C3b, C4b, and C5b-9 membranolytic attack complex (MAC) and demonstrates a very high C3 uptake in an vitro assay system.
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Epidemiology of the idiopathic inflammatory myopathies
Nature Reviews Rheumatology, 2023Thomas Khoo +2 more
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