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Inflammatory myopathies and lymphoma
Journal of the Neurological Sciences, 2016The inflammatory myopathies comprise a group of immune-mediated muscle diseases. Lymphoma is a term for a variety of lymphatic system malignancies. Autoimmune diseases and lymphoproliferative malignancies share a complex bidirectional relationship. A causal relationship between inflammatory mypathies and lymphoma has not been established. The diagnosis/
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Inflammatory and Toxic Myopathy
Seminars in Neurology, 2013Although muscle diseases are relatively rare, several treatable myopathies must be recognized by the clinician to maximize the possibility of restoring strength in affected patients. The inflammatory myopathies, including polymyositis, dermatomyositis, inflammatory necrotizing myopathy, and myositis in association with mixed connective tissue disease ...
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Immunopathogenesis of inflammatory myopathies
Annals of Neurology, 1995Immune-mediated mechanisms appear to play a primary role in the pathogenesis of polymyositis (PM) and dermatomyositis (DM). The serum of patients with active DM has high levels of circulating complement fragments C3b, C4b, and C5b-9 membranolytic attack complex (MAC) and demonstrates a very high C3 uptake in an vitro assay system.
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Idiopathic inflammatory myopathies
Journal of Neuroimmunology, 2011The idiopathic inflammatory myopathies (IIM) encompass a heterogeneous group of rare disorders that present with acute, subacute, or chronic muscle weakness. Besides overlapping clinical manifestations, polymyositis, dermatomyositis and autoimmune necrotizing myopathy may be associated with cancer or collagen vascular disease, and respond generally ...
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Epidemiology of the idiopathic inflammatory myopathies
Nature Reviews Rheumatology, 2023Hector Chinoy +2 more
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Predictors of cardiac involvement in idiopathic inflammatory myopathies
Frontiers in Immunology, 2023Matilde Bandeira +2 more
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