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Treatment of inflammatory myopathies
Muscle & Nerve, 1997The treatment of the immune-mediated inflammatory myopathies remains largely empirical. Corticosteroids are usually effective in polymyositis and dermatomyositis but may need to be combined with methotrexate or azathioprine in some patients. Intravenous immunoglobulin (IVIg) is effective as add-on therapy in some patients not adequately controlled with
Mastaglia, F.L. +2 more
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Idiopathic Inflammatory Myopathies
DeckerMed Neurology, 2002The idiopathic inflammatory myopathies (IIMs), also known as myositis syndromes, are a collection of heterogeneous disorders that share the common feature of chronic muscle inflammation of unknown cause. These disorders may occur in adults or children and are sometimes associated with other connective tissue disorders and a variety of cancers.
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Inflammatory myopathy in thyrotoxicosis
Neurology, 1997A 45-year-old man with a 3-month history of episodic muscle weakness, MRC grade 4/5 symmetric hip flexor weakness, elevated CK, and an inflammatory myopathy was found to have elevated free thyroxine and T3. Treatment with carbimazole resulted in complete resolution of symptoms and return of muscle power to normal. A repeat biopsy revealed resolution of
O, Hardiman +3 more
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Muscle & Nerve, 1984
AbstractWe report three patients with inflammatory myopathy who presented clinically with weakness and wasting of only one limb. The myopathy progressed over 6 months and 5 years, respectively, in two patients and was stable after 8 years in the third patient. One patient had a skin rash.
R J, Lederman +4 more
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AbstractWe report three patients with inflammatory myopathy who presented clinically with weakness and wasting of only one limb. The myopathy progressed over 6 months and 5 years, respectively, in two patients and was stable after 8 years in the third patient. One patient had a skin rash.
R J, Lederman +4 more
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Ultrasound in the Inflammatory Myopathies
Annals of the New York Academy of Sciences, 2009Dermato‐ or polymyositis must be diagnosed or ruled out early because early immunosuppressive therapy prevents irreversible muscle degeneration. Acute poly‐ and dermatomyositis are accompanied by normal or increased size, low echogenicity, and elevated perfusion of affected muscles, whereas in chronic poly‐ and dermatomyositis, the size and perfusion ...
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Idiopathic Inflammatory Myopathies
Rheumatic Disease Clinics of North America, 2019Major advances have been made in the field of idiopathic inflammatory myopathies (IIM), or myositis, that are likely to facilitate development of new therapeutic strategies that have not yet been applied in this group of diseases. These advances include new classification criteria to better identify the patients with IIM, detection of several new ...
Jiří, Vencovský +2 more
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Best Practice & Research Clinical Rheumatology, 2004
The major inflammatory myopathies of adults-dermatomyositis, polymyositis and inclusion body myositis-are uncommon and can be difficult to distinguish from many conditions that mimic them clinically. They have a high morbidity; they are not infrequently the first sign of an associated malignancy; and they may be a part of another connective tissue ...
Lisa, Christopher-Stine, Paul H, Plotz
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The major inflammatory myopathies of adults-dermatomyositis, polymyositis and inclusion body myositis-are uncommon and can be difficult to distinguish from many conditions that mimic them clinically. They have a high morbidity; they are not infrequently the first sign of an associated malignancy; and they may be a part of another connective tissue ...
Lisa, Christopher-Stine, Paul H, Plotz
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THERAPY OF INFLAMMATORY MYOPATHY
Rheumatic Disease Clinics of North America, 1994The management of the muscular and extramuscular manifestations of the inflammatory myopathies remains a challenge for the practicing rheumatologist. Although corticosteroids remain the first line of therapy, their side effects often limit their usefulness.
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1985
Inflammatory myopathies are those in which muscle cell injury is largely attributable to an inflammatory reaction and inflammatory cells are invariably present in the muscle. The inflammatory response may be elicited by viral, bacterial or parasitic infestation of muscle.
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Inflammatory myopathies are those in which muscle cell injury is largely attributable to an inflammatory reaction and inflammatory cells are invariably present in the muscle. The inflammatory response may be elicited by viral, bacterial or parasitic infestation of muscle.
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Idiopathic Inflammatory Myopathies
ContinuumThis article describes the various idiopathic inflammatory myopathies, including their clinical presentation, pathogenesis, diagnosis, and treatments. While many disorders fall under this umbrella, this article focuses on dermatomyositis, antisynthetase syndrome, immune-mediated necrotizing myopathy, polymyositis, and overlap syndrome.The diagnosis of ...
Mohammad Kian, Salajegheh +1 more
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