Results 61 to 70 of about 1,587,143 (318)

Myositis‐specific autoantibodies and their clinical associations in idiopathic inflammatory myopathies

Acta Neurologica Scandinavica, 2020
Myositis‐specific autoantibodies (MSAs) have been found to be present predominantly in patients with idiopathic inflammatory myopathies (IIMs). This study aimed to investigate the prevalence of MSAs and their associated complications in a cohort of ...
V. Wong, H. So, T. Lam, R. Yip
semanticscholar   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

Effect of sirolimus on muscle in inclusion body myositis observed with magnetic resonance imaging and spectroscopy

Journal of Cachexia, Sarcopenia and Muscle
Background Finding sensitive clinical outcome measures has become crucial in natural history studies and therapeutic trials of neuromuscular disorders.
Harmen Reyngoudt, Pierre‐Yves Baudin, Ericky Caldas de Almeida Araújo, Damien Bachasson, Jean‐Marc Boisserie, Kubéraka Mariampillai, Mélanie Annoussamy, Yves Allenbach, Jean‐Yves Hogrel, Pierre G. Carlier, Benjamin Marty, Olivier Benveniste   +11 more
doaj   +1 more source

Ryanodine receptor type 1 content decrease‐induced endoplasmic reticulum stress is a hallmark of myopathies

Journal of Cachexia, Sarcopenia and Muscle, 2023
Background Decreased ryanodine receptor type 1 (RyR1) protein levels are a well‐described feature of recessive RYR1‐related myopathies. The aim of the present study was twofold: (1) to determine whether RyR1 content is also decreased in other myopathies ...
Jeremy Vidal, Eric A. Fernandez, Martin Wohlwend, Pirkka‐Pekka Laurila, Andrea Lopez‐Mejia, Julien Ochala, Alexander J. Lobrinus, Bengt Kayser, Isabel C. Lopez‐Mejia, Nicolas Place, Nadège Zanou   +10 more
doaj   +1 more source

Molecular mechanisms in idiopathic inflammatory myopathies [PDF]

, 2014
Background: Myositis is a group of rare autoimmune diseases. Muscle weakness and fatigue are the dominant symptoms and inflammation with T cells and macrophages is a characteristic finding in muscle tissue.
Zong, Mei
core   +1 more source

Juvenile Dermatomyositis and the Inflammatory Myopathies

Seminars in neurology, 2020
The inflammatory myopathies comprise disorders of immune-mediated muscle injury. The histopathology and clinical features help distinguish them. Juvenile dermatomyositis (JDM) is the most common form of myositis in children and adolescents. Children with
Collin T. Swafford, E. Roach
semanticscholar   +1 more source

Interleukin‐6 as a Key Biomarker in Facioscapulohumeral Dystrophy: Evidence From Longitudinal Analyses

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy type 1 (FSHD1) is a progressive neuromuscular disorder with no approved treatments. Identifying reliable biomarkers is critical to monitor disease severity, activity, and progression. Interleukin‐6 (IL‐6) has been proposed as a candidate biomarker, but longitudinal validation is limited ...
Jonathan Pini, Emanuela Martinuzzi, Sandra Dhifallah, Abderhmane Slioui, Angela Puma, Luisa Villa, Michele Cavalli, Andra Ezaru, Jérémy Garcia, Manuela Gambella, Federico Torre, Luca Jacopo Pavan, Nicolas Glaichenhaus, Sabrina Sacconi   +13 more
wiley   +1 more source

Inclusion body myositis – pathomechanism and lessons from genetics

Open Medicine, 2015
Inclusion body myositis is a rare, late-onset myopathy. Both inflammatory and myodegenerative features play an important role in their pathogenesis.
Murnyák Balázs, Bodoki Levente, Vincze Melinda, Griger Zoltán, Csonka Tamás, Szepesi Rita, Kurucz Andrea, Dankó Katalin, Hortobágyi Tibor   +8 more
doaj   +1 more source

Anti-SRP antibody-associated necrotizing myopathy: 2 clinical cases

Нервно-мышечные болезни, 2023
Necrotizing myopathies are a subtype of autoimmune myopathies characterized by muscle fiber necrosis with minimal infiltration by inflammatory cells on muscle biopsy. This group of myopathies is defined by flaccid palsies due to prima‑ ry skeletal muscle
F. A. Abbasov, G. V. Zemtsova, P. A. Popov, K. I. Chekhonatskaya, D. V. Kukhno, M. M. Severova, M. V. Shmyreva, A. A. Kindarova, D. Yu. Schekochikhin   +8 more
doaj   +1 more source

The EuroMyositis registry: an international collaborative tool to facilitate myositis research [PDF]

, 2017
Aims: The EuroMyositis Registry facilitates collaboration across the idiopathic inflammatory myopathy (IIM) research community. This inaugural report examines pooled Registry data.
Andersson, Helena, Benveniste, Olivier, Betteridge, Zoe E, Chinoy, Hector, Contributors, EuroMyositis, Cooper, Robert G, Danieli, Maria Giovanna, Danko, Katalin, De Paepe, Boel, debleecker, Jan L, Diederichsen, Louise Pyndt, Krogh, Niels Steen, Lamb, Janine A, Lilleker, James B, Lundberg, Ingrid E, Maurer, Britta, McCann, Liza J, McHugh, Neil, New, Paul, Oakley, Paula, Ollier, William E, Pipitone, Nicolo, Schmidt, Jens, Thuy, Nguyen Thi Phuong, Vazquez-Del Mercado, Monica, Vencovsky, Jiri, Wang, Guochun, Wedderburn, Lucy R   +27 more
core   +7 more sources