Results 71 to 80 of about 18,649 (278)

Immunohistochemical differentiation of inflammatory myopathies [PDF]

open access: yes, 2012
Background: Idiopathic inflammatory myopathies are a heterogeneous group of acquired muscle disorders with considerable overlap in the histological features, making histological diagnosis difficult at times.
Patil, Anil Kumar B.   +4 more
core   +2 more sources

Antiangiogenic VEGF Isoform in Inflammatory Myopathies

open access: yesMediators of Inflammation, 2013
Objective. To investigate expression of vascular endothelial growth factor (VEGF) antiangiogenic isoform A-165b on human muscle in idiopathic inflammatory myopathies (IIM) and to compare distribution of angiogenic/antiangiogenic VEGFs, as isoforms shifts
Nila Volpi   +9 more
doaj   +1 more source

Idiopathic Inflammatory Myopathies; Association with Overlap Myositis and Syndromes: Classification, Clinical Characteristics, and Associated Autoantibodies [PDF]

open access: yes, 2016
Idiopathic inflammatory myopathies (IIM) are traditionally identified as a group of disorders that target skeletal muscle due to autoimmune dysfunction.
Pari Basharat
core  

Dysphagia in inflammatory myopathies: Self-report, incidence and prevalence [PDF]

open access: yes, 2012
This study compared self-reported incidence and prevalence of dysphagia in inflammatory myopathy diseases with instrumental data from videofluoroscopy in a cohort of 18 patients with inflammatory myopathies (inclusion body myositis, polymyositis, and ...
Mulcahy, K.   +2 more
core   +1 more source

Heat Stress in Quail: Impacts on Health and Productivity, and Mitigation Strategies

open access: yesAnimal Research and One Health, EarlyView.
Heat stress disrupts physiological homeostasis in quail, inducing oxidative stress, immune dysregulation, and metabolic imbalance, which impair growth, reproduction, product quality, and welfare. Integrating nutritional, environmental, and genetic–epigenetic strategies enhances thermotolerance, sustains productivity, and supports climate‐smart quail ...
T. A. Eletu   +6 more
wiley   +1 more source

Investigating the Role of Type I Interferon Signaling on Muscle Disease Using Mouse Models

open access: yesArthritis &Rheumatology, EarlyView.
Objective Dysregulated type I interferon (IFN) signaling contributes to autoimmune myositis pathogenesis. We investigated the therapeutic effects of JAK inhibitors in two mouse models. We also examined how type I IFNs affect muscle vasculature. Methods Myositis was induced in major histocompatibility complex class I double transgenic ([TRE‐H‐2Kb (H ...
Rita Spathis   +11 more
wiley   +1 more source

High-plex spatial protein profiling of skeletal muscle biopsies in inflammatory myopathies using the MACSima™ imaging platform: A pilot study

open access: yesActa Neuropathologica Communications
Inflammatory myopathies represent a heterogeneous group of autoimmune disorders affecting skeletal muscle, with distinct pathological features. While muscle biopsy remains a key diagnostic tool, conventional immunohistochemical approaches are limited in ...
Monica Sciacco   +9 more
doaj   +1 more source

Role of mitochondria and oxidative stress in inflammatory myopathies [PDF]

open access: yes, 2017
Les myopathies inflammatoires sont des maladies auto-immunes rares dont le dénominateur commun est la faiblesse musculaire et l'inflammation. Leur origine n’est pas connue et les traitements sont conventionnels partiellement efficaces.
Meyer, Alain
core  

[Histological and molecular alterations in inflammatory myopathies] [PDF]

open access: yes, 2009
The histological findings in muscle biopsies of inflammatory myopathies have been divided into 2 groups: A) Endomisial infiltrates mainly by T CD8+, CD4+ and macrophages and B) Perivascular infiltrates by CD4+, B cells and macrophages.
Vazquez Del Mercado Espinosa M   +3 more
core   +1 more source

Improved Detection of Myositis‐Specific Autoantibodies Using Luciferase Immunoprecipitation Systems Assay: Comparison With Line Blot and Conventional Immunoprecipitation

open access: yesArthritis &Rheumatology, EarlyView.
Objective Myositis‐specific autoantibodies guide the diagnosis and classification of idiopathic inflammatory myopathies, but current immunoassays vary in accuracy, particularly for autoantibodies associated with interstitial lung disease. To compare the performance of the luciferase immunoprecipitation systems (LIPS) assay with line blot and ...
Peter D. Burbelo   +14 more
wiley   +1 more source

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