Results 241 to 250 of about 66,787 (287)
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Idiopathic Inflammatory Myopathies
Indian Journal of Pediatrics, 2023Idiopathic inflammatory myopathies (IIMs) are a diverse group of diseases characterized by proximal muscle weakness and inflammation in skeletal muscle. Phenotypically, the subtypes include dermatomyositis, polymyositis, inclusion body myositis, and amyopathic dermatomyositis. The most common IIM in children is juvenile dermatomyositis (JDM).
Suma Balan, Sumanth Madan
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Rivista di neurologia, 1988
The inflammatory myopathies are a heterogeneous group of disorders with recent evidence demonstrating differences in clinical features, pathologic changes, pathogenesis, and response to therapy. The inflammatory myopathies generally produce predominantly proximal, symmetric muscle weakness and wasting. Additional criteria for diagnosis include elevated
Scoppetta C. +4 more
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The inflammatory myopathies are a heterogeneous group of disorders with recent evidence demonstrating differences in clinical features, pathologic changes, pathogenesis, and response to therapy. The inflammatory myopathies generally produce predominantly proximal, symmetric muscle weakness and wasting. Additional criteria for diagnosis include elevated
Scoppetta C. +4 more
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Best Practice & Research Clinical Rheumatology, 1995
New information regarding myositis specific autoantibodies, histopathologic analysis of muscle biopsy specimens, and immunogenetic features of the different serologic subsets of disease has greatly increased our understanding of the pathogenesis of the inflammatory myopathies.
C V, Oddis, T A, Medsger
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New information regarding myositis specific autoantibodies, histopathologic analysis of muscle biopsy specimens, and immunogenetic features of the different serologic subsets of disease has greatly increased our understanding of the pathogenesis of the inflammatory myopathies.
C V, Oddis, T A, Medsger
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Current Opinion in Neurology, 1996
As well as myositis caused by infectious agents, there is a spectrum of inflammatory myopathies representing diseases with autoimmune response. Subtypes differing in clinical features and morphological characteristics have been described. This review will emphasize new advances and recent efforts to identify pathogenetic mechanisms and immunological ...
D S, Tews, H H, Goebel
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As well as myositis caused by infectious agents, there is a spectrum of inflammatory myopathies representing diseases with autoimmune response. Subtypes differing in clinical features and morphological characteristics have been described. This review will emphasize new advances and recent efforts to identify pathogenetic mechanisms and immunological ...
D S, Tews, H H, Goebel
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Idiopathic inflammatory myopathies
Nature Reviews Disease Primers, 2021Idiopathic inflammatory myopathies (IIM), also known as myositis, are a heterogeneous group of autoimmune disorders with varying clinical manifestations, treatment responses and prognoses. Muscle weakness is usually the classical clinical manifestation but other organs can be affected, including the skin, joints, lungs, heart and gastrointestinal tract,
Ingrid E. Lundberg +7 more
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Current Treatment Options in Neurology, 2011
The mainstay of treatment for the idiopathic inflammatory myopathies currently and traditionally has been therapeutics aimed at suppressing or modifying the immune system. Most therapies being used are directed towards polymyositis (PM) and dermatomyositis (DM), as there is yet to be efficacious treatment of any kind for inclusion body myositis (IBM ...
B Jane, Distad +2 more
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The mainstay of treatment for the idiopathic inflammatory myopathies currently and traditionally has been therapeutics aimed at suppressing or modifying the immune system. Most therapies being used are directed towards polymyositis (PM) and dermatomyositis (DM), as there is yet to be efficacious treatment of any kind for inclusion body myositis (IBM ...
B Jane, Distad +2 more
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Continuum, 2022
This article outlines the salient clinical, serologic, electrophysiologic, imaging, and histopathologic findings and treatment options for the idiopathic inflammatory myopathies, including those related to immune checkpoint inhibitors and SARS-CoV-2.The classification of idiopathic inflammatory myopathies has improved with the integration of myositis ...
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This article outlines the salient clinical, serologic, electrophysiologic, imaging, and histopathologic findings and treatment options for the idiopathic inflammatory myopathies, including those related to immune checkpoint inhibitors and SARS-CoV-2.The classification of idiopathic inflammatory myopathies has improved with the integration of myositis ...
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Current Treatment Options in Neurology, 1999
Patients with polymyositis or dermatomyositis should be treated with prednisone (approximately 1 mg/kg/d) for an initial period of 4 to 6 weeks. Once improvement occurs, the dose should be tapered and converted to an alternate-day regimen, which should be continued for at least 12 months.
, Mastaglia, , Phillips, , Zilko
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Patients with polymyositis or dermatomyositis should be treated with prednisone (approximately 1 mg/kg/d) for an initial period of 4 to 6 weeks. Once improvement occurs, the dose should be tapered and converted to an alternate-day regimen, which should be continued for at least 12 months.
, Mastaglia, , Phillips, , Zilko
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Veterinary Clinics of North America: Small Animal Practice, 2002
Inflammatory myopathies are the result of infiltration of inflammatory cells into striated muscle, with or without an association with an underlying cause. Two broad classifications are IIMs and secondary inflammatory myopathies associated with other diseases.
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Inflammatory myopathies are the result of infiltration of inflammatory cells into striated muscle, with or without an association with an underlying cause. Two broad classifications are IIMs and secondary inflammatory myopathies associated with other diseases.
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IDIOPATHIC INFLAMMATORY MYOPATHIES
Neurologic Clinics, 1997Dermatomyositis, polymyositis, and inclusion body myositis are the major categories of idiopathic inflammatory myopathy. These inflammatory myopathies are distinct clinically, histologically, and pathogenically. Features of dermatomyositis and polymyositis can overlap with those of other autoimmune connective tissue diseases.
A A, Amato, R J, Barohn
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