Results 221 to 230 of about 58,972 (283)

Nonclinical Considerations for Support of Pregnancy and Lactation in Clinical Trials

Birth Defects Research, Volume 118, Issue 6, June 2026.
ABSTRACT Background Pregnant and breastfeeding individuals remain underrepresented in clinical drug development, leaving health care providers and patients with limited data to inform treatment decisions. Current practice relies heavily on nonclinical developmental and reproductive toxicity (DART) studies in animals, while clinical trials typically ...
Dinesh Stanislaus, Christopher J. Bowman, Kimberly C. Brannen, Sarah N. Campion, Laura M. Carlson, Stephan Chalon, Anthony M. DeLise, Claudia Demarta‐Gatsi, Brian P. Enright, Wendy Halpern, Shermaine Mitchell‐Ryan, Vicki Sutherland, Karen Thacker, Kary Thompson, Belen Tornesi, Steven Van Cruchten, Ronald L. Wange, Tacey White, Connie L. Chen   +18 more
wiley   +1 more source

Fulminant Tetraplegia in a Patient on Infliximab: A Case of Masked Cervical Spinal Epidural Abscess Presenting With Dysphagia. [PDF]

Cureus
Dubois C, Lievens P.
europepmc   +1 more source

Intraosseous sarcoidosis imitating peri‐implantitis: A case study

Clinical Advances in Periodontics, Volume 16, Issue 2, Page 251-259, June 2026.
Abstract Background Sarcoidosis is a multisystem granulomatous disorder of unknown cause, typically affecting the lungs and lymph nodes, but it can also involve the eyes, skin, heart, bones, and other organs. The exact cause is unclear, but genetic factors and environmental triggers like infections, chemicals, or dust may play a role.
Magdalena Orlowska, David S. Gottlieb, Kenneth S. Kornman   +2 more
wiley   +1 more source

Bayesian prior elicitation on the efficacy of medical therapies in perianal fistulizing Crohn's disease. [PDF]

J Crohns Colitis
Noor NM, Zheng H, Cao Z, Caruso G, Voller C, Cooney R, Din S, Gordon H, Kok KB, Lindsay JO, Moran GW, Patel KV, Sebastian S, Raine T, Subramanian S, Hart AL, Robertson DS, Parkes M.   +17 more
europepmc   +1 more source

ERDHEIM‐Chester Disease: Two Fatal Cases With Unusual Presentations

Clinical Case Reports, Volume 14, Issue 6, June 2026.
Fluorodeoxyglucose positron emission tomography‐computed tomography (FDG PET‐CT) demonstrated markedly increased metabolic activity in serosal surfaces including pericardium, pleura, and renal fascia, as well as diffuse uptake along vascular walls, particularly the entire aorta.
Ribero‐Vargas Daniel Andres, C. Álvarez Payares José, Murillo‐Pérez Juliana   +2 more
wiley   +1 more source

Fc-gamma receptors type3A (rs396991) genotyping for predicting infliximab efficacy and immunogenicity in ulcerative colitis: An observational study of Iraqi cohort. [PDF]

Medicine (Baltimore)
Al-Jalehawi AK, Mohammed SI.
europepmc   +1 more source

Bilateral Avascular Necrosis of the Femoral Heads in Ankylosing Spondylitis Requiring Staged Total Hip Arthroplasty: A Case Report of Diagnostic and Therapeutic Challenges

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Ankylosing spondylitis (AS) is a chronic immune‐mediated inflammatory arthropathy primarily affecting the axial skeleton but may involve peripheral joints, particularly the hips. Avascular necrosis (AVN) of the femoral head represents a severe, underrecognized complication whose pathogenesis in AS is multifactorial—encompassing disease ...
Syeda Simrah Shah, Muhammad Ahsan, Tehreem Farooq, Mirza Daniyal Baig, Mirza Mohammad Ali Baig, Mohammed Hammad Jaber Amin   +5 more
wiley   +1 more source

Isoniazid‐Related Secondary Drug‐Induced Autoimmune Hepatitis in a Patient Diagnosed With Ankylosing Spondylitis and Tuberculous Lymphadenitis: A Case Report

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Autoimmune hepatitis is a type of chronic hepatitis that is usually progressive, has unknown etiology, and can occur at any age. In the present case, drug‐associated autoimmune hepatitis (DIAIH) was discussed, and DIAIH secondary to isoniazid (INH) was found in two case reports in the literature.
Murat AY, Erhan Bozkurt
wiley   +1 more source

Infliximab-induced lupus with recurrent pericarditis: longitudinal CMR assessment of inflammatory resolution. [PDF]

Int J Cardiovasc Imaging
Mendpara V, El Roumi J, Klein A.
europepmc   +1 more source

A snapshot of subcutaneous infliximab uses in inflammatory rheumatic diseases: a multicentric Italian study. [PDF]

Ther Adv Musculoskelet Dis
Gentileschi S, Gaggiano C, Placido F, Terribili R, Cometi L, Lopalco G, Dipietrangelo G, Cozzi G, Padoan R, Bixio R, Parisi S, Ditto MC, Lepri G, Fabiani C, Cantarini L, Iannone F, Ramonda R, Frediani B, Guiducci S.   +18 more
europepmc   +1 more source