Results 31 to 40 of about 10,871 (266)
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Journal of Marine Science and EngineeringWhen droughts occur, freshwater inputs to coastal wetlands can become scarce and hypersalinity can become a problem. In 2023, a severe drought negatively affected a Texas watershed known as Lake Austin that fed a large expanse of wetlands on East ...
Rusty A. Feagin +5 more
doaj +1 more source
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
Baltic sea deep salinity: an initial and boundary value problem
Frontiers in Earth ScienceThe Baltic Sea salinity is modelled using a two-box model. The simplistic approach allows for very long integrations where a large part of the phase space of the model can be probed. Particular emphasis is put on the salinity dynamics in the deeper parts
Magnus Hieronymus
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Portfolio Inflows Eclipsing Banking Inflows: Alternative Facts? [PDF]
IMF Working Papers, 2018 Superficial examination of aggregate gross cross-border capital inflow data suggests that there was no substitution between portfolio inflows and bank loans in recent years. However, our novel analysis of disaggregate inflows (both by types of instrument and borrower) shows interesting heterogeneity.
Eugenio Cerutti, Gee Hee Hong
openaire +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
FEBS Open Bio, EarlyView.Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
Volatılıty Spıllovers from The Internatıonal Capıtal Inflows to Economıc Growth in Turkey
International Business and Accounting Research Journal, 2017 This paper empirically investigates the volatility interactions between the international capital inflows to Turkey and Turkish economic growth using the post-financial-liberalization era data.
Arif Orçun Söylemez
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Jurnal Ekonomi Pembangunan: Kajian Masalah Ekonomi dan Pembangunan, 2021 Before the monetary crisis in 1998, ASEAN was one of the main objectives of Foreign Direct Investment (FDI) and after the crisis, FDI inflows in ASEAN were still fluctuating, but tended to slowly increase. However, in 2009, there was a drastic decline in
Andryan Setyadharma, Silvia Nur Fadhilah
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Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
FEBS Open Bio, EarlyView.The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source