Results 61 to 70 of about 570,997 (263)

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

How Influential Are Mental Models on Interaction Performance? Exploring the Gap between Users’ and Designers’ Mental Models through a New Quantitative Method

open access: yesAdvances in Human-Computer Interaction, 2017
The objective of this study is to investigate the effect of the gap between two different mental models on interaction performance through a quantitative way.
Bingjun Xie, Jia Zhou, Huilin Wang
doaj   +1 more source

Peculiarities of millimeter range autodynes

open access: yesВестник Самарского университета: Аэрокосмическая техника, технологии и машиностроение, 2016
A functional diagram and an equivalent circuit diagram of an autodyne oscillator are presented in the paper. Features of the formation of autodyne and noise characteristics are discussed taking into account the nonlinearity of autodyne phase ...
K. A. Ignatkov
doaj   +1 more source

Interval Influence Diagrams [PDF]

open access: yes, 1990
We describe a mechanism for performing probabilistic reasoning in influence diagrams using interval rather than point valued probabilities. We derive the procedures for node removal (corresponding to conditional expectation) and arc reversal (corresponding to Bayesian conditioning) in influence diagrams where lower bounds on probabilities are stored at
openaire   +1 more source

Unconstrained Influence Diagrams

open access: yes, 2012
Appears in Proceedings of the Eighteenth Conference on Uncertainty in Artificial Intelligence (UAI2002)
Jensen, Finn Verner, Vomlelova, Marta
openaire   +2 more sources

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Optimization of Technological Parameters of Power Efficient Roller Mill

open access: yesИзвестия высших учебных заведений и энергетических объединенний СНГ: Энергетика, 2004
Milling process in the closed cycle of a roller mill has been analyzed and its diagram has been drawn up. The diagram objectively shows influence of all factors on milling process.
P. E. Vaitekhovich, V. S. Frantskevich
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Theoretical Determination of Forming Limit Stress Diagram for Steel 1021 Sheet

open access: yesTikrit Journal of Engineering Sciences, 2013
Forming limit stress diagram represent the maximum acceptable limits of  principal stresses in sheet metal forming. This diagram show the limits of major and minor true stresses for different strain paths (uniaxial tension, plane strain and equibiaxial ...
Anas O. Balod
doaj  

Simplification of State Transition Diagrams in Average Unavailability Analysis by Using Generalized Perturbation Theory

open access: yesScience and Technology of Nuclear Installations, 2014
Safety analysis studies in nuclear engineering, more specifically system reliability, usually handle a great number of components, so that computational difficulties may arise.
R. C. Vicente   +3 more
doaj   +1 more source

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